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NB: This vacancy closed to applications on 28/02/2021.

Clinical Research Facility (CRF) Junior Research Physician

Job Reference: 196-MED2293

Guy's and St. Thomas' NHS Foundation Trust
Cross site - Guy's Hospital & St. Thomas' Hospital, London
£49,036 p.a. excl. LZ

The commitment of our 17,100 staff is key to our success. We are one of the largest local employers and we aim to develop and support all our staff so they are able to deliver high quality, safe and efficient care. The 2018 NHS staff survey results show that we have one of the most engaged and motivated workforces in the NHS. We know this has a positive impact on the care provided to our patients.


Clinical Research Facility (CRF) Junior Research Physician

Nodal Point – 4 - £49,036 p.a. excl. LZ

Full Time – 40 hrs

Fixed Term – 18 months

The NIHR Clinical Research Facility (CRF) at Guy’s and St. Thomas’ NHS Foundation Trust is looking to appoint a new CRF Junior Research Physician. This is an excellent opportunity for a doctor with recent experience in acute medicine to gain experience of clinical research, including world-leading early phase trials, across a broad range of medical specialities within the supportive environment of a leading teaching and research hospital. The position provides the post holder with the opportunity to be involved in the testing of treatments and interventions that could shape the healthcare of tomorrow.

The post holder will work alongside experienced Principal Investigators (PI) within a multidisciplinary team and contribute to the clinical operations of our units. The post holder will provide medical support for patients and healthy volunteers participating in the clinical trials running in our units.

The CRF incorporates our Medicines and Healthcare products Regulatory Agency (MHRA) accredited Phase I unit. Supporting the activity of the Phase I unit is a core component of the Junior CRF Research Physician role providing the post holder the opportunity to work with novel and advanced therapies (including cell and gene therapies) prior to market authorisation. As part of this work, the post holder will support risk assessments, developing and implementing critical risk mitigation strategies for new early phase studies; this will include trials employing advanced therapies under the oversight of first-in-human accredited investigators.

The post holder will work collaboratively with our management team to shape and guide the service as we expand the scope and breadth of the service. The post holder will be actively encouraged to contribute to the work of the UK Clinical Research Network (UKCRF) working groups and present relevant outcomes at national conferences.

The post would suit doctors aiming for a career in Clinical Pharmacology, Translational Medicine or Pharmaceutical medicine. It may also suit a General Practitioner looking to explore new career opportunities or a junior doctor looking for an engaging and informative rotation in clinical research.

COVID-19 diagnostic, vaccine and therapeutic research

Clinical research is at the forefront of finding methods of diagnosing, preventing and treating COVID-19. This effort requires collaboration across campuses, infrastructure, teams and organisations. The post holder will be expected to work flexibly in order to lead these collaborations. The post holder may be asked to work remotely, in multiple locations, flexible hours or with a variety of teams. A flexible working policy including time in lieu and unsocial enhancements will be used to manage any unsocial hours worked.

The COVID-19 study portfolio is dynamic and includes rapid start up timelines and frequent amendments. The post holder will be expected to respond to these demands in a timely manner with great attention to detail.

While our organisation continues to respond to the COVID-19 pandemic and supports Urgent Public Health (UPH) and COVID-19 studies the post holder will be required to work within and on behalf of the CRF. The post holder should anticipate the majority, if not all, of their portfolio of studies will be comprised of UPH and COVID-19 studies for the duration of our organisation’s response to the COVID-19 pandemic. These studies may need to be delivered outside of the CRF.

Once COVID-19 research activity subsides, the post holder will work on a portfolio of clinical trials across a variety of therapeutic areas. Their portfolio will reflect the CRF’s strategic focus on experimental medicine and early phase clinical trials.

We strongly encourage any interested applicants to contact us to arrange an informal visit to our facility.

For further information and to apply online, please go to our website quoting reference number MED2293.


Closing date: 28th February 2021, by midnight.


As an organisation we are committed to developing our services in ways that best suit the needs of our patients. This means that some staff groups will increasingly be asked to work a more flexible shift pattern so that we can offer services in the evenings or at weekends.

Creating a world-leading Academic Health Sciences Centre.

All our vacancies can be viewed on our website.

Our excellent benefits include final salary pension scheme. Please visit our website to find out more.

Equality of opportunity is our Policy. The Trust provides health services to a diverse community.

Please note that successful completion of the International English Language Testing System (IELTS) is our accepted minimum language requirement.

For further details / informal visits contact:

NameDr Henry FokJob titleConsultant Clinical PharmacologyEmail addressHenry.Fok@nhs.netTelephone number02071882600

Applications are welcomed from applicants with a disability. We can make reasonable adjustments and offer support and advice in a variety of ways throughout the application process. Equality of opportunity is our policy.

As an organisation we are committed to developing our services in ways that best suit the needs of our patients. This means that some staff groups will increasingly be asked to work a more flexible shift pattern so that we can offer services in the evenings or at weekends.

Your e-mail address is important to us - We communicate to all job applicants via the e-mail address which has been provided on the application form. Please ensure that you check your e-mail on a regular basis.

Please apply for this post by clicking "Apply Online Now."

Disclosure and Barring Service Check

This post is subject to the Rehabilitation of Offenders Act (Exceptions Order) 1975 and as such it will be necessary for a submission for Disclosure to be made to the Disclosure and Barring Service (formerly known as CRB) to check for any previous criminal convictions.

Tier 2 Certificate of Sponsorship

Applications from job seekers who require current Tier 2/skilled worker sponsorship to work in the UK are welcome and will be considered alongside all other applications. For further information please visit the UK Visas and Immigration website.

From 6 April 2017, Tier 2/skilled worker applicants, applying for entry clearance into the UK, have had to present a criminal record certificate from each country they have resided continuously or cumulatively for 12 months or more in the past 10 years. Adult dependants (over 18 years old) are also subject to this requirement.

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