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NB: This vacancy closed to applications on 23/11/2020.


Job Reference: 196-BRC1486

Guy's and St. Thomas' NHS Foundation Trust
Guy's Hospital, London
£37,638 - £44,780 p.a. inc. HCA

The commitment of our 17,100 staff is key to our success. We are one of the largest local employers and we aim to develop and support all our staff so they are able to deliver high quality, safe and efficient care. The 2018 NHS staff survey results show that we have one of the most engaged and motivated workforces in the NHS. We know this has a positive impact on the care provided to our patients.

The NIHR GSTT Biomedical Research Centre (BRC) at Guy's and St Thomas’ NHS Foundation Trust and King's College London delivers world class translational research. Within this context, the BRC Translational Bioinformatics Platform focuses on translational research projects based on genomics and bioinformatics approaches for the identification of novel therapeutic targets and disease biomarkers, and the dissection of molecular mechanisms underpinning diseases.

The BRC’s research spans nine research themes encompassing Cardiovascular Disease; Cutaneous Medicine; Genomic Medicine; Imaging Sciences; Infection & Immunity; Transplantation; Oral Health; Regenerative Medicine & Cellular Therapy; and Women and Children’s Health.

A position is currently available in the Translational Bioinformatics group for a bioinformatician. The post will involve bioinformatics analysis of data from high throughput multi omics experiments (including single cell data) being generated as part of translational medicine studies. The post holder will implement NGS analysis pipelines making use of the Kings High Performance Computing infrastructure, where appropriate. The position also involves downstream bioinformatics analyses (for example pathway and network analysis) for data interpretation, contextualisation and hypothesis generation.

The successful candidate will have a MSc or PhD or equivalent experience, in bioinformatics, mathematics, statistics, or in a biological science with substantial computational components, will enjoy team working and interacting with clinicians and experimental biologists on analysis of complex real-world datasets, and will have significant experience in one of R/Bioconductor, Python, and familiarity with Unix. Experience of implementing NGS analysis workflows including single cell analyses, would be an advantage.

The group works in a highly collaborative manner, and the postholder will work closely with a wide range of academic and clinical researchers in addition to members of the translational bioinformatics group. The post holder will be encouraged to participate in preparing work for publication and for presentation at relevant scientific meetings.

For further details / informal visits contact:

NameDr. Mansoor SaqiAdditional contact information

For additional information please contact: Dr. Mansoor Saqi, Head of Translational Bioinformatics:

Applications are welcomed from applicants with a disability. We can make reasonable adjustments and offer support and advice in a variety of ways throughout the application process. Equality of opportunity is our policy.

As an organisation we are committed to developing our services in ways that best suit the needs of our patients. This means that some staff groups will increasingly be asked to work a more flexible shift pattern so that we can offer services in the evenings or at weekends.

Your e-mail address is important to us - We communicate to all job applicants via the e-mail address which has been provided on the application form. Please ensure that you check your e-mail on a regular basis.

Please apply for this post by clicking "Apply Online Now."

Disclosure and Barring Service Check

This post is subject to the Rehabilitation of Offenders Act (Exceptions Order) 1975 and as such it will be necessary for a submission for Disclosure to be made to the Disclosure and Barring Service (formerly known as CRB) to check for any previous criminal convictions.

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