Synnovis Analytics

Clinical Bioinformatician

Information:

This job is now closed

Job summary

We are looking for two highly motivated Clinical Scientists in bioinformatics to join our expanding Bioinformatics team at the South East Genomic Laboratory Hub (SEGLH), currently based at Guy's Hospital but with a planned move to a hub at Blackfriars.

The posts will be part of the team supporting the clinical diagnostics services of both Guy's and King's College Hospitals covering several rare disease and cancer diagnostic laboratories. You would have the opportunity to develop and troubleshoot both somatic and germline pipelines, develop and manage applications supporting the diagnostic process and manage large datasets for reporting.

The successful applicants will be dedicated and enthusiastic with knowledge and experience of working with NGS pipelines and large datasets, and strong programming and troubleshooting experience. Applicants should be good communicators, be able to take initiative, support continual quality improvement and prioritise workload. The role requires consistent attention to detail and excellent organisational skills.

This is an exciting opportunity to join a dynamic team which is highly valued in Synnovis Genomics. The successful candidates will support existing diagnostic services in the South East and also be involved in a very active programme of assay and technology development.

Applicants will be expected to have attained or be working towards passing HCPC registration. STP trainees in their final year of training are encouraged to apply.

Main duties of the job

The role involves maintaining and operating the bioinformatics pipelines for the processing of next generation sequencing data for both Guys and King's College Hospitals, managing multiple pipelines supporting services for the Genomic Medicine Service.

The post-holders will work with other clinical scientists to support the development, validation and implementation of new/updated diagnostic tests. This will include developing and delivering validated software for delivery of diagnostic services following clinical best practice guidelines as well as working with cloud-based infrastructure, local databases and the latest technologies to deliver bioinformatics services.

We support a flexible, hybrid working pattern. The role is based at the Guy's Hospital site, however occasional travel to other Synnovis sites, such as King's College Hospital may be requested.

About us

Synnovis is a pathology partnership between SYNLAB UK and Ireland, and the NHS, including sites, Guy's & St Thomas' NHS Foundation Trust and King's College Hospital NHS Foundation Trust, to deliver and transform pathology services across South East London.

You will have a suite of learning opportunities available through The Synnovis Way Development programme, the Scientific Learning and Development Fund and the Synnovis Academy through which you can receive funding / support for advanced qualifications.

Through our Innovation Accelerator Fund, you can apply for finance to get that new innovative scientific project off the ground, and participate with the wider scientific community through symposiums, conferences and other peer group meetings.

Applications are welcomed from applicants with a disability.We can make reasonable adjustments and offer support and advice in a variety of ways throughout the application process. All applicants are welcome to apply regardless of age, disability, gender, marital status, race, nationality or ethnic origin, religion, or sexual orientation. Equality of opportunity is our policy.

For our Permanent workforce we offer a competitive benefits package.

All employees are entitled to:

  • Contributory pension scheme
  • Generous annual leave entitlement
  • Ground breaking personal development opportunities

Details

Date posted

12 March 2024

Pay scheme

Agenda for change

Band

Band 6

Salary

Depending on experience £51,488 to £57,802 depending on experience

Contract

Permanent

Working pattern

Full-time

Reference number

J206-VIS5224

Job locations

Guys Hospital

London

SE1 9RT


Job description

Job responsibilities

At Synnovis, we are currently shaping the future of pathology services by creating a world-leading Hub and Spoke pathology network with our NHS partners. A large part of this modernisation will involve moving 70% of our services to a purpose built, state of the art Hub laboratory in the heart of London. For now, the job you are applying for will be based at one of our hospital sites however, from 1 April 2024 our people and services will start to move to our Hub laboratory in Blackfriars, Southwark, SE1, with some work remaining in refurbished essential services laboratories across our hospital network, focusing on the rapid turnover of urgent tests. Please do ask your recruiting manager if you wish to find out more.

The post holder will be working within a team of bioinformaticians supporting Synnovis Genomics services based across Guys and St Thomas Hospital Foundation Trusts and Kings College Hospital. This role will be a mix of acting as duty bioinformatician, development work and data analysis supporting rare disease and cancer diagnostics. The duty bioinformatician ensures the smooth operational delivery of the service and answers daily issues raised by the scientific teams. Development work includes working on new and updating existing pipelines, database projects, evaluations of applications or infrastructure planning. Supporting scientific and clinical teams is also an important part of the role, requiring strong data analysis and presentation skills.

It is likely that the majority of the role will be supporting the development of the service but individuals will need to cover all aspects of the role. Having a broad set of programming skills and IT knowledge will be required. They will be responsible for ensuring that all work is completed to a high standard within defined timelines. The post holder will be expected to work efficiently as part of the bioinformatics team and as a supportive team member.

Job description

Job responsibilities

At Synnovis, we are currently shaping the future of pathology services by creating a world-leading Hub and Spoke pathology network with our NHS partners. A large part of this modernisation will involve moving 70% of our services to a purpose built, state of the art Hub laboratory in the heart of London. For now, the job you are applying for will be based at one of our hospital sites however, from 1 April 2024 our people and services will start to move to our Hub laboratory in Blackfriars, Southwark, SE1, with some work remaining in refurbished essential services laboratories across our hospital network, focusing on the rapid turnover of urgent tests. Please do ask your recruiting manager if you wish to find out more.

The post holder will be working within a team of bioinformaticians supporting Synnovis Genomics services based across Guys and St Thomas Hospital Foundation Trusts and Kings College Hospital. This role will be a mix of acting as duty bioinformatician, development work and data analysis supporting rare disease and cancer diagnostics. The duty bioinformatician ensures the smooth operational delivery of the service and answers daily issues raised by the scientific teams. Development work includes working on new and updating existing pipelines, database projects, evaluations of applications or infrastructure planning. Supporting scientific and clinical teams is also an important part of the role, requiring strong data analysis and presentation skills.

It is likely that the majority of the role will be supporting the development of the service but individuals will need to cover all aspects of the role. Having a broad set of programming skills and IT knowledge will be required. They will be responsible for ensuring that all work is completed to a high standard within defined timelines. The post holder will be expected to work efficiently as part of the bioinformatics team and as a supportive team member.

Person Specification

Qualifications

Essential

  • HCPC Registration (or working towards registration)
  • BSc in bioinformatics, biological sciences or related field

Desirable

  • PhD in bioinformatics, biological sciences or related field

Experience

Essential

  • Experience of analysing next generation sequence data
  • Experience of developing, implementing and maintaining bioinformatic data analysis pipelines

Desirable

  • Developing cloud-based genomics apps, e.g. on AWS and DNAnexus
  • Experience in scientific workflow languages for genomic pipelines (e.g. Nextflow

Skills

Essential

  • Ability to use scripting languages such as Python and Bash
  • Ability to trouble shoot and independently solve problems
Person Specification

Qualifications

Essential

  • HCPC Registration (or working towards registration)
  • BSc in bioinformatics, biological sciences or related field

Desirable

  • PhD in bioinformatics, biological sciences or related field

Experience

Essential

  • Experience of analysing next generation sequence data
  • Experience of developing, implementing and maintaining bioinformatic data analysis pipelines

Desirable

  • Developing cloud-based genomics apps, e.g. on AWS and DNAnexus
  • Experience in scientific workflow languages for genomic pipelines (e.g. Nextflow

Skills

Essential

  • Ability to use scripting languages such as Python and Bash
  • Ability to trouble shoot and independently solve problems

Disclosure and Barring Service Check

This post is subject to the Rehabilitation of Offenders Act (Exceptions Order) 1975 and as such it will be necessary for a submission for Disclosure to be made to the Disclosure and Barring Service (formerly known as CRB) to check for any previous criminal convictions.

Certificate of Sponsorship

Applications from job seekers who require current Skilled worker sponsorship to work in the UK are welcome and will be considered alongside all other applications. For further information visit the UK Visas and Immigration website (Opens in a new tab).

From 6 April 2017, skilled worker applicants, applying for entry clearance into the UK, have had to present a criminal record certificate from each country they have resided continuously or cumulatively for 12 months or more in the past 10 years. Adult dependants (over 18 years old) are also subject to this requirement. Guidance can be found here Criminal records checks for overseas applicants (Opens in a new tab).

Additional information

Disclosure and Barring Service Check

This post is subject to the Rehabilitation of Offenders Act (Exceptions Order) 1975 and as such it will be necessary for a submission for Disclosure to be made to the Disclosure and Barring Service (formerly known as CRB) to check for any previous criminal convictions.

Certificate of Sponsorship

Applications from job seekers who require current Skilled worker sponsorship to work in the UK are welcome and will be considered alongside all other applications. For further information visit the UK Visas and Immigration website (Opens in a new tab).

From 6 April 2017, skilled worker applicants, applying for entry clearance into the UK, have had to present a criminal record certificate from each country they have resided continuously or cumulatively for 12 months or more in the past 10 years. Adult dependants (over 18 years old) are also subject to this requirement. Guidance can be found here Criminal records checks for overseas applicants (Opens in a new tab).

Employer details

Employer name

Synnovis Analytics

Address

Guys Hospital

London

SE1 9RT


Employer's website

http://www.synnovis.co.uk/ (Opens in a new tab)

Employer details

Employer name

Synnovis Analytics

Address

Guys Hospital

London

SE1 9RT


Employer's website

http://www.synnovis.co.uk/ (Opens in a new tab)

Employer contact details

For questions about the job, contact:

GLH Bioinformatics Lead

Rebecca Haines

rebecca.haines1@nhs.net

Details

Date posted

12 March 2024

Pay scheme

Agenda for change

Band

Band 6

Salary

Depending on experience £51,488 to £57,802 depending on experience

Contract

Permanent

Working pattern

Full-time

Reference number

J206-VIS5224

Job locations

Guys Hospital

London

SE1 9RT


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