Experimental Medicine Division - University of Oxford

Clinical Research Fellow

The closing date is 09 January 2026

Job summary

Based at John Radcliffe Hospital, you will contribute to clinical research in airways diseases within the Respiratory Medicine Unit, working with teams within Oxford Centre for Respiratory Medicine.

The post will support studies led by Professor Petousi &Professor Pavord: the Oxford airways study on phenotyping of airways diseases and a randomised controlled trial of dupilumab in patients with high-risk type-2 high asthma (HOTHOT). You will recruit participants, conduct research visits as a medically-qualified investigator, support trial delivery and data collection, undertake laboratory work, analyse data, and contribute to reports and publications. You will also run research clinics for patients with asthma and COPD and work with multidisciplinary collaborators.

It is expected that you are eligible to undertake clinical practice in the UK (having General Medical Council registration or proven eligibility for registration). Successful applicants will be required to hold an honorary clinical contract and therefore must ensure that they can fulfil all the criteria required by the GMC, their LETB and the National Health Service Trust.

Main duties of the job

  • Be responsible for the recruitment of eligible participants for the HOTHOT randomised-controlled clinical trial from Oxford University Hospitals, and through collaboration with primary care.
  • Conduct research visits for the HOTHOT study and Oxford airways study as a medically-qualified Investigator and support the research nurses with the scheduled activities, queries and completion of CRFs.
  • Undertake laboratory experiments, according to experimental protocols relevant to the research project.
  • Collect and analyse data as required for the project.
  • Write progress reports for the HOTHOT study, as required and participate in relevant meetings.
  • Accept technical training in necessary methods, where appropriate, as well as mandatory training as required
  • Run research clinics for patients with asthma and COPD and communication with collaborators locally and nationally.
  • Write papers and contribute to publications and participate in seminars and conferences
  • Work effectively within the team and with collaborators, which may include supporting or supervising junior members of the team on a day to day basis
  • Regular meetings with project supervisors regarding progress of project & attend relevant group meetings and knowledge of relevant literature
  • Participate in and support the public engagement and widening access activities of the Department and the University. This is anticipated to be not more than 2 days per year.

About us

The post will be located in the Respiratory Medicine Unit (RMU), which is led by Professor Ian Pavord. The RMU is situated in the John Radcliffe Hospital, where there is a dedicated clinical research area for airways diseases (Level 2) and a wet laboratory (including a sputum lab) at Level 7. The unit receives support from the NIHR Biomedical Research Centre, with a dedicated Respiratory Theme. It comprises 3 Principal Investigators (Professors Ian Pavord, Tim Hinks and Nayia Petousi). The groups research interests are in translational research in asthma and COPD, and aims to enahnce understanding of airway pathobiology, improve diagnosis, phenotyping and patient stratification and ultimately the targeting of therapies to the right patients at the right time. It builds on excellent clinical programmes in airways diseases, clinical randomized trials of therapeutic agents, as well as cutting-edge basic science in respiratory immunology and respiratory physiology.

We were the first to identify eosinophilic, type-2 high airway inflammation as a key treatable trait in patients with asthma and COPD. We recognised that this pattern of airway inflammation is associated with an increased risk of exacerbations of airway disease and corticosteroid responsiveness.

Details

Date posted

18 December 2025

Pay scheme

Other

Salary

£38,831 to £73,992 a year

Contract

Fixed term

Duration

12 months

Working pattern

Full-time, Flexible working

Reference number

N0041-183830

Job locations

Nuffield Department of Clinical Medicine - Experimental Medicine Division

John Radcliffe Hospital (Room 5800, Level 5)

Oxford

OX3 9DU


Job description

Job responsibilities

About the role

Based at John Radcliffe Hospital, you will contribute to clinical research in airways diseases within the Respiratory Medicine Unit, working with teams within Oxford Centre for Respiratory Medicine.

The post will support studies led by Professor Petousi &Professor Pavord: the Oxford airways study on phenotyping of airways diseases and a randomised controlled trial of dupilumab in patients with high-risk type-2 high asthma (HOTHOT). You will recruit participants, conduct research visits as a medically-qualified investigator, support trial delivery and data collection, undertake laboratory work, analyse data, and contribute to reports and publications. You will also run research clinics for patients with asthma and COPD and work with multidisciplinary collaborators.

It is expected that you are eligible to undertake clinical practice in the UK (having General Medical Council registration or proven eligibility for registration). Successful applicants will be required to hold an honorary clinical contract and therefore must ensure that they can fulfil all the criteria required by the GMC, their LETB and the National Health Service Trust.

About you

To be considered for this position you should hold an undergraduate degree with honours in medicine. You should have clinical experience at ST3+ level or equivalent, but not hold CCT or consultant status with a strong academic record.

You should have significant experiences of patient and public facing activities, both in clinical and non-clinical settings, including PPIE. Along with evidence of interdisciplinary and collaborative working, both within clinical and research settings.

Benefits of working

University employees enjoy 38 days paid holiday, generous pension schemes, travel discounts, and a variety of professional development opportunities. Our range of other employee benefits and discounts also includes free entry to the Botanic Gardens and University colleges, and discounts at University museums. Seehttps://hr.admin.ox.ac.uk/staff-benefits

Job description

Job responsibilities

About the role

Based at John Radcliffe Hospital, you will contribute to clinical research in airways diseases within the Respiratory Medicine Unit, working with teams within Oxford Centre for Respiratory Medicine.

The post will support studies led by Professor Petousi &Professor Pavord: the Oxford airways study on phenotyping of airways diseases and a randomised controlled trial of dupilumab in patients with high-risk type-2 high asthma (HOTHOT). You will recruit participants, conduct research visits as a medically-qualified investigator, support trial delivery and data collection, undertake laboratory work, analyse data, and contribute to reports and publications. You will also run research clinics for patients with asthma and COPD and work with multidisciplinary collaborators.

It is expected that you are eligible to undertake clinical practice in the UK (having General Medical Council registration or proven eligibility for registration). Successful applicants will be required to hold an honorary clinical contract and therefore must ensure that they can fulfil all the criteria required by the GMC, their LETB and the National Health Service Trust.

About you

To be considered for this position you should hold an undergraduate degree with honours in medicine. You should have clinical experience at ST3+ level or equivalent, but not hold CCT or consultant status with a strong academic record.

You should have significant experiences of patient and public facing activities, both in clinical and non-clinical settings, including PPIE. Along with evidence of interdisciplinary and collaborative working, both within clinical and research settings.

Benefits of working

University employees enjoy 38 days paid holiday, generous pension schemes, travel discounts, and a variety of professional development opportunities. Our range of other employee benefits and discounts also includes free entry to the Botanic Gardens and University colleges, and discounts at University museums. Seehttps://hr.admin.ox.ac.uk/staff-benefits

Person Specification

Qualifications

Essential

  • An undergraduate degree with honours in Medicine.
  • Eligible to undertake clinical practice in the UK (having General Medical Council registration or proven eligibility for registration). Successful applicants will be required to hold an honorary clinical contract and therefore must ensure that they can fulfill all the criteria required by the GMC, their LETB and the National Health Service Trust;
  • Clinical experience at ST3+ level or equivalent, but not hold CCT or consultant status.

Desirable

  • Hold a Bachelor in Science degree.
  • Hold MRCP or equivalent, with higher specialist training in respiratory medicine and/or interest in relevant therapeutic interest (however applicants from any clinical specialty will be considered).

Experience

Essential

  • A strong academic record as evidenced by undergraduate degree and/or research outputs
  • Hold significant experiences of patient and public facing activities, both in clinical and non-clinical settings, including PPIE.
  • Evidence of interdisciplinary and collaborative working, both within clinical and research settings, but also with colleagues from non-clinical technical disciplines.
  • Excellent communication and writing skills, including the ability to write text that can be published, present data at conferences, and represent the research group at meetings.
  • Demonstrable interest in clinical trial research and excellent data analytic skills

Desirable

  • Demonstrated significant interest and passion for Respiratory research.
  • Experiences of working in diverse clinical settings.
  • Possess an understanding of scientific disciplines and how they can be applied to healthcare research
  • Experience in clinical trials.
  • Experience in wet-lab research.
Person Specification

Qualifications

Essential

  • An undergraduate degree with honours in Medicine.
  • Eligible to undertake clinical practice in the UK (having General Medical Council registration or proven eligibility for registration). Successful applicants will be required to hold an honorary clinical contract and therefore must ensure that they can fulfill all the criteria required by the GMC, their LETB and the National Health Service Trust;
  • Clinical experience at ST3+ level or equivalent, but not hold CCT or consultant status.

Desirable

  • Hold a Bachelor in Science degree.
  • Hold MRCP or equivalent, with higher specialist training in respiratory medicine and/or interest in relevant therapeutic interest (however applicants from any clinical specialty will be considered).

Experience

Essential

  • A strong academic record as evidenced by undergraduate degree and/or research outputs
  • Hold significant experiences of patient and public facing activities, both in clinical and non-clinical settings, including PPIE.
  • Evidence of interdisciplinary and collaborative working, both within clinical and research settings, but also with colleagues from non-clinical technical disciplines.
  • Excellent communication and writing skills, including the ability to write text that can be published, present data at conferences, and represent the research group at meetings.
  • Demonstrable interest in clinical trial research and excellent data analytic skills

Desirable

  • Demonstrated significant interest and passion for Respiratory research.
  • Experiences of working in diverse clinical settings.
  • Possess an understanding of scientific disciplines and how they can be applied to healthcare research
  • Experience in clinical trials.
  • Experience in wet-lab research.

Disclosure and Barring Service Check

This post is subject to the Rehabilitation of Offenders Act (Exceptions Order) 1975 and as such it will be necessary for a submission for Disclosure to be made to the Disclosure and Barring Service (formerly known as CRB) to check for any previous criminal convictions.

Certificate of Sponsorship

Applications from job seekers who require current Skilled worker sponsorship to work in the UK are welcome and will be considered alongside all other applications. For further information visit the UK Visas and Immigration website (Opens in a new tab).

From 6 April 2017, skilled worker applicants, applying for entry clearance into the UK, have had to present a criminal record certificate from each country they have resided continuously or cumulatively for 12 months or more in the past 10 years. Adult dependants (over 18 years old) are also subject to this requirement. Guidance can be found here Criminal records checks for overseas applicants (Opens in a new tab).

UK Registration

Applicants must have current UK professional registration. For further information please see NHS Careers website (opens in a new window).

Additional information

Disclosure and Barring Service Check

This post is subject to the Rehabilitation of Offenders Act (Exceptions Order) 1975 and as such it will be necessary for a submission for Disclosure to be made to the Disclosure and Barring Service (formerly known as CRB) to check for any previous criminal convictions.

Certificate of Sponsorship

Applications from job seekers who require current Skilled worker sponsorship to work in the UK are welcome and will be considered alongside all other applications. For further information visit the UK Visas and Immigration website (Opens in a new tab).

From 6 April 2017, skilled worker applicants, applying for entry clearance into the UK, have had to present a criminal record certificate from each country they have resided continuously or cumulatively for 12 months or more in the past 10 years. Adult dependants (over 18 years old) are also subject to this requirement. Guidance can be found here Criminal records checks for overseas applicants (Opens in a new tab).

UK Registration

Applicants must have current UK professional registration. For further information please see NHS Careers website (opens in a new window).

Employer details

Employer name

Experimental Medicine Division - University of Oxford

Address

Nuffield Department of Clinical Medicine - Experimental Medicine Division

John Radcliffe Hospital (Room 5800, Level 5)

Oxford

OX3 9DU


Employer's website

https://www.expmedndm.ox.ac.uk/about (Opens in a new tab)

Employer details

Employer name

Experimental Medicine Division - University of Oxford

Address

Nuffield Department of Clinical Medicine - Experimental Medicine Division

John Radcliffe Hospital (Room 5800, Level 5)

Oxford

OX3 9DU


Employer's website

https://www.expmedndm.ox.ac.uk/about (Opens in a new tab)

Employer contact details

For questions about the job, contact:

HR Team

HR Team

exp.med-hr@ndm.ox.ac.uk

Details

Date posted

18 December 2025

Pay scheme

Other

Salary

£38,831 to £73,992 a year

Contract

Fixed term

Duration

12 months

Working pattern

Full-time, Flexible working

Reference number

N0041-183830

Job locations

Nuffield Department of Clinical Medicine - Experimental Medicine Division

John Radcliffe Hospital (Room 5800, Level 5)

Oxford

OX3 9DU


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