Job summary
The School of Biosciences and Chemistryare looking to appoint a Research Fellow in the Biomolecular Sciences Research Centre, working on a project funded by the Humane Research Trust to develop animal-free models for the testing of new immunotherapies in the treatment of bowel cancer. You will contribute to an ongoing programme of research geared towards the use of human tissue to model human disease, promoting the development of new methods to replace the use of animals in medical research and delivering solutions that are both more humane and support better scientific in an area where current models have poor translation into patients with bowel cancer.
Main duties of the job
As Research Fellow you will take the lead on liaising with clinical collaborators, collection of clinical material, processing and development of cell models using patient-derived material. Youll be supported to develop your own interests in this field, with a view to developing your own independent research career. Youll work in a team committed to producing high quality research outputs in the form of academic publications, conference presentations, and lead in a field with growing influence over governmental policy around humane medical research.
We are seeking a candidate with experience in cell biology and practical skills in microscopy and flow cytometry, preferably in the context of advanced models such as 3D matrix scaffolds and organoids. Knowledge of cancer biology would be desirable, and an up-to-date interest in cancer treatments such as immunotherapy would also be an advantage.
Experience working with primary clinical samples including tissue and blood samples - would also be an advantage, and a commitment to flexible working patterns around sample availability is essential. Knowledge of working within the Human Tissue Act and evidence of good record-keeping are also key skills, as is experience working within inter-disciplinary teams in order to support the clinic-model pipeline.
About us
The School of Biosciences and Chemistry provides courses in applied biological and chemical sciences, all delivered in a supportive, research-informed environment. The School consists of approximately 50 academic staff, active in research and with an excellent reputation for teaching.
We deliver a wide range of courses preparing applied science graduates for professional roles in biosciences, healthcare, chemistry sectors and beyond.
Our research is aimed at increasing understanding of the molecular and cellular basis of health and disease and its application to diagnosis, monitoring and treatment. We have excellent cell culture facilities enabling us to undertake clinical sample processing, cell modelling, flow sorting of immune cells and biochemical analysis of these human-relevant model systems.
In addition, you will be join a network of researchers working with charitable organizations committed to delivering more humane research methods, and advocating for the reduction of animals used in pre-clinical medical research.
Details
Date posted
02 March 2026
Pay scheme
Other
Salary
£39,906 to £46,049 a year
Contract
Fixed term
Duration
24 months
Working pattern
Full-time, Flexible working
Reference number
N0013-116967
Job locations
City Campus
Howard Street
Sheffield
South Yorkshire
S1 1WB
Employer details
Employer name
Sheffield Hallam University
Address
City Campus
Howard Street
Sheffield
South Yorkshire
S1 1WB
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