UK Health Security Agency

Senior Health Economist

The closing date is 10 November 2025

Job summary

Following approval of the Genomics Strategy, the Genomics programme has been underway since June 2024. The programme aims to deliver integrated end to end pathogen genomics in three priority areas (emerging infections, vaccines and antimicrobial resistance) as well as systematic organisational transformation in genomics delivery, infrastructure and workforce. UKHSA is providing UK and global leadership for pathogen genomics for diagnostic and surveillance purposes with the work underpinned by health economics, cost effectiveness and value for money.

This post will be located within UKHSA's Central Economics Team and will work under a matrix management arrangement with UKHSA's TARZET (TB, Acute Respiratory, Rare & Imported Pathogens, Emerging Infection & Zoonosis, Travel Health & IHR, and Genomics Public Health Analysis) Division and the Pathogen Genomics Programme, delivering jointly agreed objectives. We are looking for an economist to lead development of the economic evidence underpinning the Pathogen Genomics programme and help the team to deliver analysis in support of public health decision making.

You will work with other experts (bioinformaticians, epidemiologists, data scientists and public health experts) to assess the economic costs and benefits of genomics programmes being developed in response to pressing health security problems, and to help build our understanding of how new and innovative technologies can be best deployed to support the public's health.

Main duties of the job

To support the adoption of these technologies, you will lead a work programme to build the evidence base around them such as improving estimates of the value of pathogen genomic surveillance or the benefits that come from diagnostic services.

For instance, a core part of the role will be leading development of economic cases for UKHSA's key Pathogen Genomics programme including the metagenomics Surveillance Collaboration and Analysis Programme (mSCAPE), a collaborative programme piloting the use of metagenomic data for public health surveillance and pathogen analysis.

The use of the five-part business case model is still relatively new in the Agency and so you will also have a role in championing Green Book approaches and appraisal best practice for cases as well as developing the tools, guidance and other capability the Agency needs to make the most out of adopting the model.

This is a great opportunity to be part of a growing service which is building the organisation's economics capability and a chance to shape its culture. As a new role, there will be some flexibility in the work undertaken though this also comes with the ability for the post-holder to shape the role towards their interests.

About us

We pride ourselves as being an employer of choice, where Everyone Matters promoting equality of opportunity to actively encourage applications from everyone, including groups currently underrepresented in our workforce.

UKHSA ethos is to be an inclusive organisation for all our staff and stakeholders. To create, nurture and sustain an inclusive culture, where differences drive innovative solutions to meet the needs of our workforce and wider communities. We do this through celebrating and protecting differences by removing barriers and promoting equity and equality of opportunity for all.

Please visit our careers site for more information https://gov.uk/ukhsa/careers

Details

Date posted

27 October 2025

Pay scheme

Other

Salary

£56,185 to £70,566 a year per annum, pro rata

Contract

Fixed term

Duration

16 months

Working pattern

Full-time, Part-time, Job share, Flexible working

Reference number

919-LT-62055193-EXT

Job locations

Core HQs

Birmingham, Leeds, Liverpool, London (Canary Wharf)

E14 4PU


Job description

Job responsibilities

One of the key programmes of work requiring robust economic evaluation is the mSCAPE programme. mSCAPE is an internationally leading programme to pilot the use of clinical metagenomic data for public health surveillance and biosecurity. It was publicly launched on 30 January 2025 and is now live, receiving data from the NHS sites to a new central data platform. It works in partnership with three universities and the NHS Genomics Network of Excellence rollout of diagnostic metagenomics.

The aims of the programme are to evaluate the use of metagenomics for public health surveillance, to rapidly detect new viruses or bacteria that may be a threat to public health. Whilst traditional molecular diagnostics may identify parts of a viral or bacterial genome by e.g. polymerase chain reaction (PCR), and whole genome sequencing (WGS) sequences the genome of a particular known viral or bacterial pathogen, metagenomics sequences all the genetic material present in a particular sample. This technique is therefore pathogen agnostic and provides an important and exciting opportunity to identify novel pathogens.

As part of the evaluation of the use of this technique for public health surveillance, an understanding of the economic costs and benefits is crucial. You will lead a value for money evaluation for the next phase and expansion of the project over 25/26 and 26/27. This may include literature reviews of existing studies, and undertaking primary research to establish the cost benefit of this approach. This evaluation will then be used to develop a business case for future development and use of this technology.

The role will also provide support to the wider Pathogen Genomics programme and projects as required, including projects developing metagenomics diagnostic services, and environmental surveillance.

The type of work you can expect to lead and support on includes:

  • Developing robust economic cases using the latest evidence for UKHSA projects and programmes
  • Managing stakeholders including within the Department for Health and Social Care
  • Producing cost-benefit and cost-effectiveness analysis to guide UKHSA decision-making in reducing the spread of infectious diseases
  • Producing materials to build the agencys capability to produce economic cases, including training materials, templates and bespoke guidance.
  • Communicating your work with senior stakeholders and Ministers in a clear, convincing manner
  • Establishing quality assurance processes and providing advice on analysis and research produced by others

Detailed job description and main responsibilities

Lead a work programme building UKHSAs economic evidence base

You will apply existing methods, and identify new approaches, to provide insight to important health questions. There will be some scope for the postholder to shape this work according to their interest, while also meeting the likely future demands of the programme team. It could include looking at new ways to value the benefits of surveillance programmes or the importance of building resilience. You will demonstrate an ability to manage projects and stakeholders across an organisation, and bring a strong intellectual curiosity with an interdisciplinary approach.

Develop Economic Cases for projects and programmes

You will work across the organisation on developing economic cases for key genomics projects and programmes as part of the standard HMG five-part business case process. Mostly focused on applying your knowledge of economics and Green Book guidance to assess benefits and costs of different options and help the organisation come to a preferred approach. You will need to provide advice and quality assurance to some cases primarily written by other teams while for other cases you will take the lead on drafting.

Provide analysis, insight and challenge

You are open to learning more about the health domain from other experts while demonstrating the value that economics can bring to public health questions. You will need to develop clear high-quality analysis and be willing to challenge that of others.

Build the Economic profession at UKHSA

All the while, you will be at the forefront of building the role and reputation of the economic profession within UKHSA. Working with experts across multiple fields, you will showcase the value of economics to all colleagues as well as contributing to building an inclusive and welcoming community of economists.

Essential Criteria

  • Experience in cost-benefit and/or cost-effectiveness analysis, particularly relating to health interventions
  • Knowledge of health economics and experience in applying it to provide insight into complex health problems.
  • Ability to work at pace to deadlines across multiple projects
  • Ability to effectively communicate the results of analysis to senior stakeholders and decision-makers
  • Good interpersonal skills and the ability to develop and maintain key stakeholder relationships
  • A first or second class honours degree in economics or related field (or equivalent qualification) or a postgraduate degree in a relevant numerate discipline.

Desirable Criteria

  • Experience with developing Green Book-compliant business cases including knowledge of best practice.
  • Experience in line management, including managing specialists such as economists
  • Experience in running and leading research programmes and/or managing projects across an organisation
  • Experience or knowledge of public health surveillance or interventions for infectious diseases especially those using genomics e.g. through work on global emerging pathogens, acute respiratory & imported diseases or other biosecurity issues.

Selection Process Details

This vacancy is using Success Profiles and will assess your Behaviours, Experience and Technical skills.

Stage 1: Application & Sift

Success Profiles - GOV.UK

You will be required to complete an application form. You will be assessed on the listed 6 essential criteria, and this will be in the form of a:

  • Application form (Employer/ Activity history section on the application)
  • 1000 word supporting statement.

This should outline how your skills, experience and knowledge provide evidence of your suitability for the role, with reference to the essential criteria.

The Application form and supporting statement will be marked together.

Longlisting: In the event of a large number of applications we will longlist into 3 piles of:

  • Meets all essential criteria
  • Meets some essential criteria
  • Meets no essential criteria

If longlisting is used, the pile meets all essential criteria will proceed to shortlisting.

Shortlisting: In the event of a large number of applications we may complete an initial sift on the lead criteria:

  • Knowledge of health economics and experience in applying it to provide insight into complex health problems.
  • Ability to effectively communicate the results of analysis to senior stakeholders and decision-makers

Desirable criteria may be used in the event of a large number of applications/large amount of successful candidates.

If you are successful at this stage, you will progress to interview & assessment.

Healthjobs UK has a word limit of 1500, but your supporting statement must be no more than 1000 words.

Feedback will not be provided at this stage.

Stage 2: Interview

Success Profiles

You will be invited to a (single) remote interview.

Behaviours and technical skills will be tested at interview.

Technical ability will be assessed via a presentation. You will be asked to prepare and present a 510 minute presentation. The subject of this will be sent to you prior to interview

The Behaviours tested during the interview stage will be

  • Seeing the big picture
  • Making effective decisions
  • Communicating and influencing
  • Delivering at pace

Interview dates to be confirmed.

Once this job has closed, the job advert will no longer be available. You may want to save a copy for your records.

Selection Process

Please note you will not be able to upload your CV. You must complete the application form in as much detail as possible. Please do not email us your CV.

Eligibility Criteria

External Open to all external applicants (anyone) from outside the Civil Service (including by definition internal applicants).

Location

This role is being offered as hybrid working based at any of our Core HQs. We offer great flexible working opportunities at UKHSA and operate using a hybrid working model where business needs allow. This provides us with greater flexibility about how and where we work, to get the best from our workforce. As a hybrid worker, you will be expected to spend a minimum of 60% of your contractual working hours (approximately 3 days a week pro rata, averaged over a month) working at one of UKHSA's core HQs (Birmingham, Leeds, Liverpool, and London).

Our core HQ offices are modern and newly refurbished with excellent city centre transport link and benefit from benefit from co-location with other government departments such as the Department for Health and Social Care (DHSC).

Security Clearance Level Requirement

Successful candidates must pass a disclosure and barring security check.

Successful candidates must meet the security requirements before they can be appointed. The level of security needed is Basic Personnel Security Standard.

Salary Information/Bands

Grade 7

  • National £56,185 - £66,581
  • Outer £58,340 - £68,574
  • Inner £60,494 - £70,566

If you are successful at interview, and are moving from another government department, NHS, or Local Authority, the relevant starting salary principles for level transfers or promotions will apply. Otherwise, roles are offered at the pay scale minimum for the grade, but in exceptional circumstances there may be flexibility if you are able to demonstrate you are already in receipt of an existing, higher salary. Pay increases are through the relevant annual pay award for the role and terms.

Job description

Job responsibilities

One of the key programmes of work requiring robust economic evaluation is the mSCAPE programme. mSCAPE is an internationally leading programme to pilot the use of clinical metagenomic data for public health surveillance and biosecurity. It was publicly launched on 30 January 2025 and is now live, receiving data from the NHS sites to a new central data platform. It works in partnership with three universities and the NHS Genomics Network of Excellence rollout of diagnostic metagenomics.

The aims of the programme are to evaluate the use of metagenomics for public health surveillance, to rapidly detect new viruses or bacteria that may be a threat to public health. Whilst traditional molecular diagnostics may identify parts of a viral or bacterial genome by e.g. polymerase chain reaction (PCR), and whole genome sequencing (WGS) sequences the genome of a particular known viral or bacterial pathogen, metagenomics sequences all the genetic material present in a particular sample. This technique is therefore pathogen agnostic and provides an important and exciting opportunity to identify novel pathogens.

As part of the evaluation of the use of this technique for public health surveillance, an understanding of the economic costs and benefits is crucial. You will lead a value for money evaluation for the next phase and expansion of the project over 25/26 and 26/27. This may include literature reviews of existing studies, and undertaking primary research to establish the cost benefit of this approach. This evaluation will then be used to develop a business case for future development and use of this technology.

The role will also provide support to the wider Pathogen Genomics programme and projects as required, including projects developing metagenomics diagnostic services, and environmental surveillance.

The type of work you can expect to lead and support on includes:

  • Developing robust economic cases using the latest evidence for UKHSA projects and programmes
  • Managing stakeholders including within the Department for Health and Social Care
  • Producing cost-benefit and cost-effectiveness analysis to guide UKHSA decision-making in reducing the spread of infectious diseases
  • Producing materials to build the agencys capability to produce economic cases, including training materials, templates and bespoke guidance.
  • Communicating your work with senior stakeholders and Ministers in a clear, convincing manner
  • Establishing quality assurance processes and providing advice on analysis and research produced by others

Detailed job description and main responsibilities

Lead a work programme building UKHSAs economic evidence base

You will apply existing methods, and identify new approaches, to provide insight to important health questions. There will be some scope for the postholder to shape this work according to their interest, while also meeting the likely future demands of the programme team. It could include looking at new ways to value the benefits of surveillance programmes or the importance of building resilience. You will demonstrate an ability to manage projects and stakeholders across an organisation, and bring a strong intellectual curiosity with an interdisciplinary approach.

Develop Economic Cases for projects and programmes

You will work across the organisation on developing economic cases for key genomics projects and programmes as part of the standard HMG five-part business case process. Mostly focused on applying your knowledge of economics and Green Book guidance to assess benefits and costs of different options and help the organisation come to a preferred approach. You will need to provide advice and quality assurance to some cases primarily written by other teams while for other cases you will take the lead on drafting.

Provide analysis, insight and challenge

You are open to learning more about the health domain from other experts while demonstrating the value that economics can bring to public health questions. You will need to develop clear high-quality analysis and be willing to challenge that of others.

Build the Economic profession at UKHSA

All the while, you will be at the forefront of building the role and reputation of the economic profession within UKHSA. Working with experts across multiple fields, you will showcase the value of economics to all colleagues as well as contributing to building an inclusive and welcoming community of economists.

Essential Criteria

  • Experience in cost-benefit and/or cost-effectiveness analysis, particularly relating to health interventions
  • Knowledge of health economics and experience in applying it to provide insight into complex health problems.
  • Ability to work at pace to deadlines across multiple projects
  • Ability to effectively communicate the results of analysis to senior stakeholders and decision-makers
  • Good interpersonal skills and the ability to develop and maintain key stakeholder relationships
  • A first or second class honours degree in economics or related field (or equivalent qualification) or a postgraduate degree in a relevant numerate discipline.

Desirable Criteria

  • Experience with developing Green Book-compliant business cases including knowledge of best practice.
  • Experience in line management, including managing specialists such as economists
  • Experience in running and leading research programmes and/or managing projects across an organisation
  • Experience or knowledge of public health surveillance or interventions for infectious diseases especially those using genomics e.g. through work on global emerging pathogens, acute respiratory & imported diseases or other biosecurity issues.

Selection Process Details

This vacancy is using Success Profiles and will assess your Behaviours, Experience and Technical skills.

Stage 1: Application & Sift

Success Profiles - GOV.UK

You will be required to complete an application form. You will be assessed on the listed 6 essential criteria, and this will be in the form of a:

  • Application form (Employer/ Activity history section on the application)
  • 1000 word supporting statement.

This should outline how your skills, experience and knowledge provide evidence of your suitability for the role, with reference to the essential criteria.

The Application form and supporting statement will be marked together.

Longlisting: In the event of a large number of applications we will longlist into 3 piles of:

  • Meets all essential criteria
  • Meets some essential criteria
  • Meets no essential criteria

If longlisting is used, the pile meets all essential criteria will proceed to shortlisting.

Shortlisting: In the event of a large number of applications we may complete an initial sift on the lead criteria:

  • Knowledge of health economics and experience in applying it to provide insight into complex health problems.
  • Ability to effectively communicate the results of analysis to senior stakeholders and decision-makers

Desirable criteria may be used in the event of a large number of applications/large amount of successful candidates.

If you are successful at this stage, you will progress to interview & assessment.

Healthjobs UK has a word limit of 1500, but your supporting statement must be no more than 1000 words.

Feedback will not be provided at this stage.

Stage 2: Interview

Success Profiles

You will be invited to a (single) remote interview.

Behaviours and technical skills will be tested at interview.

Technical ability will be assessed via a presentation. You will be asked to prepare and present a 510 minute presentation. The subject of this will be sent to you prior to interview

The Behaviours tested during the interview stage will be

  • Seeing the big picture
  • Making effective decisions
  • Communicating and influencing
  • Delivering at pace

Interview dates to be confirmed.

Once this job has closed, the job advert will no longer be available. You may want to save a copy for your records.

Selection Process

Please note you will not be able to upload your CV. You must complete the application form in as much detail as possible. Please do not email us your CV.

Eligibility Criteria

External Open to all external applicants (anyone) from outside the Civil Service (including by definition internal applicants).

Location

This role is being offered as hybrid working based at any of our Core HQs. We offer great flexible working opportunities at UKHSA and operate using a hybrid working model where business needs allow. This provides us with greater flexibility about how and where we work, to get the best from our workforce. As a hybrid worker, you will be expected to spend a minimum of 60% of your contractual working hours (approximately 3 days a week pro rata, averaged over a month) working at one of UKHSA's core HQs (Birmingham, Leeds, Liverpool, and London).

Our core HQ offices are modern and newly refurbished with excellent city centre transport link and benefit from benefit from co-location with other government departments such as the Department for Health and Social Care (DHSC).

Security Clearance Level Requirement

Successful candidates must pass a disclosure and barring security check.

Successful candidates must meet the security requirements before they can be appointed. The level of security needed is Basic Personnel Security Standard.

Salary Information/Bands

Grade 7

  • National £56,185 - £66,581
  • Outer £58,340 - £68,574
  • Inner £60,494 - £70,566

If you are successful at interview, and are moving from another government department, NHS, or Local Authority, the relevant starting salary principles for level transfers or promotions will apply. Otherwise, roles are offered at the pay scale minimum for the grade, but in exceptional circumstances there may be flexibility if you are able to demonstrate you are already in receipt of an existing, higher salary. Pay increases are through the relevant annual pay award for the role and terms.

Person Specification

Application form and supporting statement

Essential

  • Application form and supporting statement

Behaviours

Essential

  • Seeing the big picture
  • Making effective decisions
  • Communicating and influencing
  • Delivering at pace
Person Specification

Application form and supporting statement

Essential

  • Application form and supporting statement

Behaviours

Essential

  • Seeing the big picture
  • Making effective decisions
  • Communicating and influencing
  • Delivering at pace

Disclosure and Barring Service Check

This post is subject to the Rehabilitation of Offenders Act (Exceptions Order) 1975 and as such it will be necessary for a submission for Disclosure to be made to the Disclosure and Barring Service (formerly known as CRB) to check for any previous criminal convictions.

Certificate of Sponsorship

Applications from job seekers who require current Skilled worker sponsorship to work in the UK are welcome and will be considered alongside all other applications. For further information visit the UK Visas and Immigration website (Opens in a new tab).

From 6 April 2017, skilled worker applicants, applying for entry clearance into the UK, have had to present a criminal record certificate from each country they have resided continuously or cumulatively for 12 months or more in the past 10 years. Adult dependants (over 18 years old) are also subject to this requirement. Guidance can be found here Criminal records checks for overseas applicants (Opens in a new tab).

Additional information

Disclosure and Barring Service Check

This post is subject to the Rehabilitation of Offenders Act (Exceptions Order) 1975 and as such it will be necessary for a submission for Disclosure to be made to the Disclosure and Barring Service (formerly known as CRB) to check for any previous criminal convictions.

Certificate of Sponsorship

Applications from job seekers who require current Skilled worker sponsorship to work in the UK are welcome and will be considered alongside all other applications. For further information visit the UK Visas and Immigration website (Opens in a new tab).

From 6 April 2017, skilled worker applicants, applying for entry clearance into the UK, have had to present a criminal record certificate from each country they have resided continuously or cumulatively for 12 months or more in the past 10 years. Adult dependants (over 18 years old) are also subject to this requirement. Guidance can be found here Criminal records checks for overseas applicants (Opens in a new tab).

Employer details

Employer name

UK Health Security Agency

Address

Core HQs

Birmingham, Leeds, Liverpool, London (Canary Wharf)

E14 4PU


Employer's website

https://www.gov.uk/government/organisations/uk-health-security-agency (Opens in a new tab)

Employer details

Employer name

UK Health Security Agency

Address

Core HQs

Birmingham, Leeds, Liverpool, London (Canary Wharf)

E14 4PU


Employer's website

https://www.gov.uk/government/organisations/uk-health-security-agency (Opens in a new tab)

Employer contact details

For questions about the job, contact:

Resourcing Support Officer

Lisa Tweedie

Lisa.Tweedie@ukhsa.gov.uk

Details

Date posted

27 October 2025

Pay scheme

Other

Salary

£56,185 to £70,566 a year per annum, pro rata

Contract

Fixed term

Duration

16 months

Working pattern

Full-time, Part-time, Job share, Flexible working

Reference number

919-LT-62055193-EXT

Job locations

Core HQs

Birmingham, Leeds, Liverpool, London (Canary Wharf)

E14 4PU


Supporting documents

Privacy notice

UK Health Security Agency's privacy notice (opens in a new tab)