UK Health Security Agency

Bioinformatician (mSCAPE development)

The closing date is 05 November 2025

Job summary

This post is an exciting bioinformatician role in the mSCAPE (TARZET) division, enabling the team to deliver cutting edge analysis in support of public health decision making, with a particular focus on outbreak response, horizon scanning, emerging infections and developmental genomics work. Work within the mSCAPE team is fast paced, responding quickly to changing public health needs.

Functions of the team include horizon scanning, cluster analysis, used together with epidemiological investigation, to inform the understanding of how viruses are being transmitted throughout the population; development of new analysis methods for emerging pathogens, reactive analyses for major national outbreaks, and collaborative working with epidemiology, modelling and academic partners.

Main duties of the job

Specific duties of the role may vary depending on the site and teams/functions.

  • Be responsible for day-to-day running and maintenance of the software and computer systems delivering existing genomic analysis pipelines.
  • Contribute to expanding deployment of existing analysis pipelines to additional computational platforms as required.
  • Support the identification and sharing of best bioinformatics practice.
  • Accept responsibility for refactoring existing WGS software components.
  • Develop tested, validated and versioned software components for genomic analyses, incorporate into and validate new genomic pipeline versions.
  • Satisfy support requests for genomic analysis from clinical teams.
  • Analyse data from projects to which you are assigned, accepting responsibility for generating reports within agreed timelines.
  • Lead preparation of reports, posters and publications arising from the data, and present findings.
  • Represent mSCAPE at internal, National and International meetings.
  • Work consistently with the unit quality management systems, ISO and other accreditation standards. as required; participate in quality audits to support the unit's services.
  • Comply with safety and quality protocols and procedures at all times.

About us

We pride ourselves as being an employer of choice, where Everyone Matters promoting equality of opportunity to actively encourage applications from everyone, including groups currently underrepresented in our workforce.

UKHSA ethos is to be an inclusive organisation for all our staff and stakeholders. To create, nurture and sustain an inclusive culture, where differences drive innovative solutions to meet the needs of our workforce and wider communities. We do this through celebrating and protecting differences by removing barriers and promoting equity and equality of opportunity for all.

Please visit our careers site for more information https://gov.uk/ukhsa/careers

Details

Date posted

22 October 2025

Pay scheme

Other

Salary

£46,310 to £52,113 a year per annum, pro rata (Inner)

Contract

Fixed term

Duration

17 months

Working pattern

Full-time, Part-time, Job share, Flexible working

Reference number

919-LT-62055191-EXT

Job locations

Core HQ

London (Canary Wharf)

E14 4PU


Job description

Job responsibilities

  • Identify, discuss and action own professional performance and training / development needs with your line manager through appraisal / individual development plan. Attending internal / external training events.
  • To participate in all mandatory training as required, i.e. fire safety, information governance and all other mandatory training.
  • Undergo a programme of on-going development and education to build on existing knowledge and develop skills to meet the behaviours and competencies required to undertake the role.

KEY WORKING RELATIONSHIPS

The post holder will develop working relationships and communicate regularly with a wide range of individuals, clinical and non-clinical, internal and external to UKHSA. This will require a high level of communication skills, disseminating complex technical information, and an ability to communicate complex programmatic and IT issues to non-specialist groups in layman terms.This will include;

Internal

  • Substantial interactions with members of the mSCAPE bioinformatics team and other units within the TARZET division
  • Regular interactions with Laboratory scientists, embedded bioinformaticians and epidemiologists, including during incident working.
  • Substantial interactions within DAS and with central IT (ICT) colleagues, including during incident working.

External

  • Interaction with external scientific computing experts to deliver appropriate technologies through external cloud-based resource and utilising UKHSA computing infrastructure.
  • Interactions with collaborating centres, including research and academic institutes, to deliver software process for analysing WGS data.

Essential Criteria

  • Degree in Bioinformatics or related life science.
  • Postgraduate training in Bioinformatics, or equivalent.
  • Familiar with Linux/Unix; proficient in the CLI.
  • Knowledge of Next Generation Sequencing technologies and associated bioinformatic analytical approaches.
  • Experience applying diverse bioinformatics tools, preferably to the analysis of microbial DNA.
  • Experience of developing, modifying, debugging code used for data analysis, preferably python
  • Highly motivated, enthusiastic and hard-working.
  • Interested in the advancements of medical microbiology and genomics.
  • Problem solving skills and ability to respond to sudden unexpected demands.
  • Must be able to use initiative to identify and implement tested solutions with a view to process and service improvement.
  • Must have the ability to anticipate and resolve problems before they arise.
  • Ability to analyse complex facts and situations, develop a range of options and make recommendations.

Desirable Criteria

  • Knowledge of metagenomics.
  • Experience of VCS systems (e.g. git) for software versioning and documentation.
  • Knowledge of software containerization (e.g. Docker, Singularity).
  • Knowledge of PostgreSQL or similar RDBMS

Selection Process Details

This vacancy is using Success Profiles and will assess your Behaviours, Ability, Experience and Technical skills.

Stage 1: Application & Sift

Success Profiles - GOV.UK

You will be required to complete an application form. You will be assessed on the listed 12 essential criteria, and this will be in the form of a:

  • Application form (Employer/ Activity history section on the application)
  • 750 word supporting statement.

This should outline how your skills, experience and knowledge provide evidence of your suitability for the role, with reference to the essential criteria.

The Application form and supporting statement will be marked together.

Longlisting: In the event of a large number of applications we will longlist into 3 piles of:

  • Meets all essential criteria
  • Meets some essential criteria
  • Meets no essential criteria

If longlisting is used, the piles meets all and meets some essential criteria will proceed to shortlisting.

Shortlisting: In the event of a large number of applications we will complete an initial sift on the lead criteria of:

  • Degree in Bioinformatics or related life science.
  • Postgraduate training in Bioinformatics, or equivalent.
  • Experience applying diverse bioinformatics tools, preferably to the analysis of microbial DNA.
  • Experience of developing, modifying, debugging code used for data analysis, preferably python

Desirable criteria may be used in the event of a large number of applications/large amount of successful candidates.

If you are successful at this stage, you will progress to interview & assessmentPlease do not exceed 750 words. We will not consider any words over and above this number.

Please note you will not be able to upload your CV. You must complete the application form in as much detail as possible. Please do not email us your CV.

Feedback will not be provided at this stage.

Stage 2: Interview

Success profiles

You will be invited to a single remote interview.

Behaviours, technical skills, experience and ability will be tested at interview.

There will be a Technical Test and a Presentation.

If invited to interview you will be asked to prepare a 10 minute presentation- details will be shared with those candidates invited to interview.

The Behaviours tested during the interview stage will be:

  • Changing and improving
  • Communicating and influencing
  • Delivering at pace

Interview dates to be confirmed.

Once this job has closed, the job advert will no longer be available. You may want to save a copy for your records.

Selection Process

Please note you will not be able to upload your CV. You must complete the application form in as much detail as possible. Please do not email us your CV.

Eligibility Criteria

External-Open to all external applicants (anyone) from outside the Civil Service (including by definition internal applicants). Location

This role is being offered as hybrid working based at our Core HQ in London (Canary Wharf). We offer great flexible working opportunities at UKHSA and operate using a hybrid working model where business needs allow. This provides us with greater flexibility about how and where we work, to get the best from our workforce. As a hybrid worker, you will be expected to spend a minimum of 60% of your contractual working hours (approximately 3 days a week pro rata, averaged over a month) working at our UKHSA Core HQ in London (Canary Wharf).

Our core HQ offices are modern and newly refurbished with excellent city centre transport link and benefit from benefit from co-location with other government departments such as the Department for Health and Social Care (DHSC).

Security Clearance Level Requirement

Successful candidates must pass a disclosure and barring security check.

Successful candidates must meet the security requirements before they can be appointed. The level of security needed is Basic Personnel Security Standard.

Salary Information

If you are successful at interview, and are moving from another government department, NHS, or Local Authority, the relevant starting salary principles for level transfers or promotions will apply. Otherwise, roles are offered at the pay scale minimum for the grade, but in exceptional circumstances there may be flexibility if you are able to demonstrate you are already in receipt of an existing, higher salary. Pay increases are through the relevant annual pay award for the role and terms.

Job description

Job responsibilities

  • Identify, discuss and action own professional performance and training / development needs with your line manager through appraisal / individual development plan. Attending internal / external training events.
  • To participate in all mandatory training as required, i.e. fire safety, information governance and all other mandatory training.
  • Undergo a programme of on-going development and education to build on existing knowledge and develop skills to meet the behaviours and competencies required to undertake the role.

KEY WORKING RELATIONSHIPS

The post holder will develop working relationships and communicate regularly with a wide range of individuals, clinical and non-clinical, internal and external to UKHSA. This will require a high level of communication skills, disseminating complex technical information, and an ability to communicate complex programmatic and IT issues to non-specialist groups in layman terms.This will include;

Internal

  • Substantial interactions with members of the mSCAPE bioinformatics team and other units within the TARZET division
  • Regular interactions with Laboratory scientists, embedded bioinformaticians and epidemiologists, including during incident working.
  • Substantial interactions within DAS and with central IT (ICT) colleagues, including during incident working.

External

  • Interaction with external scientific computing experts to deliver appropriate technologies through external cloud-based resource and utilising UKHSA computing infrastructure.
  • Interactions with collaborating centres, including research and academic institutes, to deliver software process for analysing WGS data.

Essential Criteria

  • Degree in Bioinformatics or related life science.
  • Postgraduate training in Bioinformatics, or equivalent.
  • Familiar with Linux/Unix; proficient in the CLI.
  • Knowledge of Next Generation Sequencing technologies and associated bioinformatic analytical approaches.
  • Experience applying diverse bioinformatics tools, preferably to the analysis of microbial DNA.
  • Experience of developing, modifying, debugging code used for data analysis, preferably python
  • Highly motivated, enthusiastic and hard-working.
  • Interested in the advancements of medical microbiology and genomics.
  • Problem solving skills and ability to respond to sudden unexpected demands.
  • Must be able to use initiative to identify and implement tested solutions with a view to process and service improvement.
  • Must have the ability to anticipate and resolve problems before they arise.
  • Ability to analyse complex facts and situations, develop a range of options and make recommendations.

Desirable Criteria

  • Knowledge of metagenomics.
  • Experience of VCS systems (e.g. git) for software versioning and documentation.
  • Knowledge of software containerization (e.g. Docker, Singularity).
  • Knowledge of PostgreSQL or similar RDBMS

Selection Process Details

This vacancy is using Success Profiles and will assess your Behaviours, Ability, Experience and Technical skills.

Stage 1: Application & Sift

Success Profiles - GOV.UK

You will be required to complete an application form. You will be assessed on the listed 12 essential criteria, and this will be in the form of a:

  • Application form (Employer/ Activity history section on the application)
  • 750 word supporting statement.

This should outline how your skills, experience and knowledge provide evidence of your suitability for the role, with reference to the essential criteria.

The Application form and supporting statement will be marked together.

Longlisting: In the event of a large number of applications we will longlist into 3 piles of:

  • Meets all essential criteria
  • Meets some essential criteria
  • Meets no essential criteria

If longlisting is used, the piles meets all and meets some essential criteria will proceed to shortlisting.

Shortlisting: In the event of a large number of applications we will complete an initial sift on the lead criteria of:

  • Degree in Bioinformatics or related life science.
  • Postgraduate training in Bioinformatics, or equivalent.
  • Experience applying diverse bioinformatics tools, preferably to the analysis of microbial DNA.
  • Experience of developing, modifying, debugging code used for data analysis, preferably python

Desirable criteria may be used in the event of a large number of applications/large amount of successful candidates.

If you are successful at this stage, you will progress to interview & assessmentPlease do not exceed 750 words. We will not consider any words over and above this number.

Please note you will not be able to upload your CV. You must complete the application form in as much detail as possible. Please do not email us your CV.

Feedback will not be provided at this stage.

Stage 2: Interview

Success profiles

You will be invited to a single remote interview.

Behaviours, technical skills, experience and ability will be tested at interview.

There will be a Technical Test and a Presentation.

If invited to interview you will be asked to prepare a 10 minute presentation- details will be shared with those candidates invited to interview.

The Behaviours tested during the interview stage will be:

  • Changing and improving
  • Communicating and influencing
  • Delivering at pace

Interview dates to be confirmed.

Once this job has closed, the job advert will no longer be available. You may want to save a copy for your records.

Selection Process

Please note you will not be able to upload your CV. You must complete the application form in as much detail as possible. Please do not email us your CV.

Eligibility Criteria

External-Open to all external applicants (anyone) from outside the Civil Service (including by definition internal applicants). Location

This role is being offered as hybrid working based at our Core HQ in London (Canary Wharf). We offer great flexible working opportunities at UKHSA and operate using a hybrid working model where business needs allow. This provides us with greater flexibility about how and where we work, to get the best from our workforce. As a hybrid worker, you will be expected to spend a minimum of 60% of your contractual working hours (approximately 3 days a week pro rata, averaged over a month) working at our UKHSA Core HQ in London (Canary Wharf).

Our core HQ offices are modern and newly refurbished with excellent city centre transport link and benefit from benefit from co-location with other government departments such as the Department for Health and Social Care (DHSC).

Security Clearance Level Requirement

Successful candidates must pass a disclosure and barring security check.

Successful candidates must meet the security requirements before they can be appointed. The level of security needed is Basic Personnel Security Standard.

Salary Information

If you are successful at interview, and are moving from another government department, NHS, or Local Authority, the relevant starting salary principles for level transfers or promotions will apply. Otherwise, roles are offered at the pay scale minimum for the grade, but in exceptional circumstances there may be flexibility if you are able to demonstrate you are already in receipt of an existing, higher salary. Pay increases are through the relevant annual pay award for the role and terms.

Person Specification

Application form and supporting statement

Essential

  • Application form and supporting statement

Behaviours

Essential

  • Changing and improving
  • Communicating and influencing
  • Delivering at pace
Person Specification

Application form and supporting statement

Essential

  • Application form and supporting statement

Behaviours

Essential

  • Changing and improving
  • Communicating and influencing
  • Delivering at pace

Disclosure and Barring Service Check

This post is subject to the Rehabilitation of Offenders Act (Exceptions Order) 1975 and as such it will be necessary for a submission for Disclosure to be made to the Disclosure and Barring Service (formerly known as CRB) to check for any previous criminal convictions.

Certificate of Sponsorship

Applications from job seekers who require current Skilled worker sponsorship to work in the UK are welcome and will be considered alongside all other applications. For further information visit the UK Visas and Immigration website (Opens in a new tab).

From 6 April 2017, skilled worker applicants, applying for entry clearance into the UK, have had to present a criminal record certificate from each country they have resided continuously or cumulatively for 12 months or more in the past 10 years. Adult dependants (over 18 years old) are also subject to this requirement. Guidance can be found here Criminal records checks for overseas applicants (Opens in a new tab).

Additional information

Disclosure and Barring Service Check

This post is subject to the Rehabilitation of Offenders Act (Exceptions Order) 1975 and as such it will be necessary for a submission for Disclosure to be made to the Disclosure and Barring Service (formerly known as CRB) to check for any previous criminal convictions.

Certificate of Sponsorship

Applications from job seekers who require current Skilled worker sponsorship to work in the UK are welcome and will be considered alongside all other applications. For further information visit the UK Visas and Immigration website (Opens in a new tab).

From 6 April 2017, skilled worker applicants, applying for entry clearance into the UK, have had to present a criminal record certificate from each country they have resided continuously or cumulatively for 12 months or more in the past 10 years. Adult dependants (over 18 years old) are also subject to this requirement. Guidance can be found here Criminal records checks for overseas applicants (Opens in a new tab).

Employer details

Employer name

UK Health Security Agency

Address

Core HQ

London (Canary Wharf)

E14 4PU


Employer's website

https://www.gov.uk/government/organisations/uk-health-security-agency (Opens in a new tab)

Employer details

Employer name

UK Health Security Agency

Address

Core HQ

London (Canary Wharf)

E14 4PU


Employer's website

https://www.gov.uk/government/organisations/uk-health-security-agency (Opens in a new tab)

Employer contact details

For questions about the job, contact:

Resourcing Support Officer

Lisa Tweedie

Lisa.Tweedie@ukhsa.gov.uk

Details

Date posted

22 October 2025

Pay scheme

Other

Salary

£46,310 to £52,113 a year per annum, pro rata (Inner)

Contract

Fixed term

Duration

17 months

Working pattern

Full-time, Part-time, Job share, Flexible working

Reference number

919-LT-62055191-EXT

Job locations

Core HQ

London (Canary Wharf)

E14 4PU


Supporting documents

Privacy notice

UK Health Security Agency's privacy notice (opens in a new tab)