The Christie NHS FT

Aseptic Practitioner

The closing date is 28 December 2025

Job summary

The successful candidate will participate in and supervise the Aseptic production of Clinical trial, SACT, EAMS, FOC and Gene therapy injectable medicines and will be responsible for the daily supervision of aseptic staff during production. In addition, they will be involved in the procurement and stock control of all drugs and consumables used for aseptic preparation.

If you have an interest in the safe manufacture of injectable medicines and a desire to develop supervisory skills to help manage a team, then this could be the role for you!

The Aseptic Services Unit at the Christie NHS Trust is a world leader in the production of phase one clinical trial material, we prepare an extensive portfolio of over 100 different trials alongside EAMS, FOC and compassionate use schemes. The ideal candidate should possess a high level of concentration, the ability to manipulate syringes and needles to withdraw liquid media and to be able to accurately read volumes on syringes.

The ability to stretch and twist is required for cleaning the facilities and the isolators.

All work is carried out in a clean room environment under the supervision of the Accountable Pharmacist and a highly trained technical team.

Main duties of the job

Preparation of worksheets and labels for aseptically prepared products
Setting up work trays for aseptically prepared products
Sanitisation and transfer of all materials required for production
Aseptic preparation of injectable materials
Cleaning of facilities and isolators prior to and post production
In process checks
Supervision of junior staff
Recording and maintaining the correct parameters to allow for aseptic manipulation within the isolators
Taking monitoring samples using TSA and SAB contact and settle plates
Procurement of stock, stock management, stock rotation and regular stock takes

About us

We are an ever-expanding multi-disciplinary team of Assistants, Practitioners, Technicians, and pharmacists who strive to produce exceptionally high-quality injectable medicines to each patient that uses our service.

The Aseptic team is a diverse and dynamic team who work in a specialised cleanroom environment where teamwork is the key to efficiency and managing the patient experience. Each day is both challenging and rewarding in equal measures, with cancer treatments constantly evolving and new types of drugs being trialled each year.

We are at the forefront of developments in terms of drug innovation and team development, we were one of the first hospitals in the country to introduce the progression role of Aseptic Practitioner to pharmacy and we are looking forward within the next year to being able to add the Science Manufacturing Technician qualification to our already large portfolio of training and staff qualifications here at The Christie

We have recently developed a career pathway for technical staff wishing to progress from band 2 up to band 8a and support all qualifications and in house developments that allow for this progression should you wish to further your career within the pharmacy aseptic team.

So, if you want to work as part of an ever-progressing team and you enjoy a challenge then we could be the team for you.

Date posted

23 December 2025

Pay scheme

Agenda for change

Band

Band 4

Salary

£27,485 to £30,162 a year per annum pro rata

Contract

Permanent

Working pattern

Full-time

Reference number

413-101092-CNS-SD-A

Job locations

Pharmacy Aseptics - E00921

Wilmslow Road

Manchester

M20 4BX

Job description

Job responsibilities

Supervision of cleanroom staff and workflow

Plan, organise and prioritise work activities within clean rooms

Ensure all processes and procedures are followed by staff operating in the ASU

Responsible for the safe use of equipment within clean rooms, ensuring clean room staff use equipment in accordance with instructions and SOPs

Ensures that all required functional tests, inspections and verifications are carried out on clean room equipment before and after work sessions.

Reports equipment faults and deviations and ensures that deviations are authorised and records are diligently completed.

Delivering products and service as part of the Aseptic team

Experience and knowledge in good manufacturing and processing procedures

To be part of the dispensing service for systemic anti-cancer therapy (SACT) requiring aseptic preparation including cytotoxic drugs, gene therapy and monoclonal antibodies from point of prescription receipt.

To be aware and follow all departmental operating procedures and Good Manufacturing Practice (GMP) guidance at all times.

To aseptically dispense products within the aseptic facilities including accurately measuring volumes and following aseptic no-touch techniques.

To be responsible for the transfer disinfection into the aseptic units of all items required for aseptic processing, following departmental processes.

To be fully aware of the COSHH regulations particularly with regard to the safe storage and handling of pharmaceutical products, to be aware of the Aseptic Spillage procedure and what to do in the event of spillage of a drug product.

Carry out environmental monitoring with swabs, contact and settle agar plates. To be responsible for sending environmental monitoring samples to Quality Control in a timely manner.

Provide support to the aseptic administration systems.

To participate in aseptic unit cleaning rota, including cleaning of the aseptic units before and after core hours, if required. To undertake regular cleaning duties carried out during the working day.

To set up and assemble work trays according to departmental SOPs in a timely and efficient manner.

To co-ordinate daily workload, managing breaks and highlighting issues of productivity slowing down to a senior technician.

To ensure adequate knowledge and understanding of clinical trials products prepared in aseptics relevant to the job role including accountability, stock control and storage requirements. To follow Good Clinical Practice (GCP) guidance and undertake where relevant data collection for aseptic clinical trial products.

To communicate effectively with healthcare professionals both within and outside the Trust. To ensure good team working with other pharmacy staff, ward staff and other service providers as necessary.

To carry out stock management including receipt, correct storage, stock count, expiry check and weekly ordering of all aseptic items including drugs, diluents and consumables.

To carry out stock ordering through multiple supply channels and monitor stock levels.

To be able to participate in the on-call rotation for making out-of-hours aseptic SACT if the service demands.

To train junior members of staff in core areas as deemed appropriate by the Aseptic Team Lead.

To contribute to bank holiday working where required.

Be available and flexible to potential move to seven day working.

Support and maintain the Quality Assurance system

To be aware of and participate, where required, in departmental audits.

To assist in the updating and reviewing of SOPs and the building of drugs in the pharmacy computer system.

To assist with annual and ad-hoc validations.

Support and assist the Aseptic team Lead

Other

To perform any other duties as requested by the line manager, Aseptic Services Manager or Director of Pharmacy.