The Christie NHS FT

Advanced Clinical Practitioner

The closing date is 27 October 2025

Job summary

This post presents an excellent opportunity to join the established and expanding Haematology Research team and the NIHR Clinical Research Facility (CRF) at the Christie NHS Foundation Trust, with a varied portfolio of early and late phase clinical trials as an Advanced Clinical Practitioner (ACP). This is a join post between the Haematology Research Department and the NIHR CRF unit. You must have proven experience as a qualified ACP and desirable experience in research and/or haematology.

This will encompass utilising advanced assessment, diagnostic and treatment skills within an agreed scope of practice. The post holder will assist in the safe referral, CRF patient review, admission or discharge of patients,attending Haematology research clinics and in patient stays.

The successful applicant will facilitate the development of clinical practice through research and education of the multi-disciplinary team. You will evaluate care through quality assurance initiatives and assessment of clinical outcome and be an expert resource for other healthcare practitioners whilst ensuring the highest standards of clinical care are delivered. The post holder will ensure the maintenance of clinical excellence and will provide specialist clinical leadership within research and haematology.

Main duties of the job

Demonstrate a critical understanding of the broadened level of responsibility and autonomy of the ACP role as well as recognising and practicing within individual limits.

Be an expert practitioner and clinical role model in the field of research in oncology and haematology, with specific expertise in haematological clinical research and the delivery of protocol defined treatments, patient management and monitoring.

Use advanced clinical skills in the assessment and management of patients in collaboration with relevant clinicalresearch teams. This includes obtaining informed consent, history taking, clinical trial screening, systematic physical examination, requisition and interpretation of appropriate clinical investigations and formulation of clinicalmanagement plans.

Perform delegated clinical trial duties as above, including protocol specific tasks as part of a clinical trial, where delegated by the Principal Investigator and approved by the Sponsor.

About us

The Christie is one of Europe's leading cancer centres, treating over 60,000 patients a year. We are based in Manchester and serve a population of 3.2 million across Greater Manchester & Cheshire, but as a national specialist around 15% patients are referred to us from other parts of the country. We provide radiotherapy through one of the largest radiotherapy departments in the world; chemotherapy on site and through 14 other hospitals; highly specialist surgery for complex and rare cancer; and a wide range of support and diagnostic services. We are also an international leader in research, with world first breakthroughs for over 100 years. We run one of the largest early clinical trial units in Europe with over 300 trials every year. Cancer research in Manchester, most of which is undertaken on the Christie site, has been officially ranked the best in the UK.

Details

Date posted

13 October 2025

Pay scheme

Agenda for change

Band

Band 8a

Salary

£55,690 to £62,682 a year Per annum, Pro rata

Contract

Permanent

Working pattern

Full-time

Reference number

413-99506-RI-DA

Job locations

Haematology - Q00675

Manchester

M20 4BX


Job description

Job responsibilities

Prescribe licenced and non-licenced drugs within the capacity of non-medical prescribing, adhering to Trust policy and existing frameworks. Prescribe appropriate blood products as per Trust policy. Engage in self-directed learning, critically reflecting to maximise clinical skills and knowledge.

Participate in the on-going advanced clinical practice training and education programme both within the organisation and beyond e.g., national/ international conferences.

Act as a principle or sub-investigator on a variety of clinical and academic research studies and proactively encourage and promote involvement by nurses in contributing to research projects.

Maintain personal standards of conduct and behaviour consistent with Trust values and regulations set within the relevant professional bodies.

1.0 Plan and manage own workload in accordance with service requirements, in a flexible manner, ensuring that service provision meets the needs of patients.1.1 Demonstrate a critical understanding of the broadened level of responsibility and autonomy of the ACP role as well as recognising and practicing within individual limits.1.2 Be an expert practitioner and clinical role model in the field of oncology, with specific expertise in clinical research and the delivery of protocol defined treatments, patientmanagement and monitoring.1.3 Be an advocate and role model for developing and delivering care that is responsive to changing requirements, informed by an understanding of local population health needs, agencies and networks.1.4 Use advanced clinical skills in the assessment and management of patients incollaboration with relevant clinical research teams. This includes obtaining informed consent, history taking, clinical trial screening, systematic physical examination, requisition and interpretation of appropriate clinical investigations and formulation of clinical management plans.1.5 Perform delegated clinical trial duties as above, including protocol specific tasks as part of a clinical trial where delegated by the Principle Investigator and approved by the Sponsor.1.6 Use expertise and decisionmaking skills to inform clinical reasoning fordifferentiated and undifferentiated presentations. Synthesise information from multiple sources to make appropriate, evidence based judgements and/or diagnosis.1.7 Prescribe licenced and non-licenced drugs within the capacity of non-medical prescribing, adhering to Trust policy and existing frameworks. Prescribe appropriate blood products as per Trust policy.1.8 Have advanced resuscitation skills and support the inter-professional team during and after an emergency event and support emergency scenario training.1.9 Liaise with the wider inter-professional teams (i.e. palliative care, critical care, junior Drs on call and out of hours team) regarding the management of patients under their care1.10 Accept referrals from other health care professionals and refer patients directly to other specialties within the appropriate primary, secondary and tertiary care settings.1.11 Communicate highly complex and sensitive information to patients and their significantothers, this may include diagnosis, results of scans or other investigations,management options and prognosis.1.12 Demonstrate effective communication skills, supporting patients and relatives in decision making, planning care or seeking to make positive health related lifestyle changes.1.13 Work collaboratively with an appropriate range of multi-agency and multi-professional resources, developing, maintaining and evaluating links to manage risk and issues across organisations and settings.1.14 Prepare accurate and concise records and reports, both verbal and written. Communicate with the patients referring specialist, GP and other community and hospice based services at regular intervals as appropriate.1.15 Contribute to clinical and research governance processes, including adverse incidentreporting and the investigation and the management of complaints as appropriate.1.16 Act on professional judgement about when to seek help, demonstrating criticalreflection on own practice, self-awareness, emotional intelligence, and openness to change.

Job description

Job responsibilities

Prescribe licenced and non-licenced drugs within the capacity of non-medical prescribing, adhering to Trust policy and existing frameworks. Prescribe appropriate blood products as per Trust policy. Engage in self-directed learning, critically reflecting to maximise clinical skills and knowledge.

Participate in the on-going advanced clinical practice training and education programme both within the organisation and beyond e.g., national/ international conferences.

Act as a principle or sub-investigator on a variety of clinical and academic research studies and proactively encourage and promote involvement by nurses in contributing to research projects.

Maintain personal standards of conduct and behaviour consistent with Trust values and regulations set within the relevant professional bodies.

1.0 Plan and manage own workload in accordance with service requirements, in a flexible manner, ensuring that service provision meets the needs of patients.1.1 Demonstrate a critical understanding of the broadened level of responsibility and autonomy of the ACP role as well as recognising and practicing within individual limits.1.2 Be an expert practitioner and clinical role model in the field of oncology, with specific expertise in clinical research and the delivery of protocol defined treatments, patientmanagement and monitoring.1.3 Be an advocate and role model for developing and delivering care that is responsive to changing requirements, informed by an understanding of local population health needs, agencies and networks.1.4 Use advanced clinical skills in the assessment and management of patients incollaboration with relevant clinical research teams. This includes obtaining informed consent, history taking, clinical trial screening, systematic physical examination, requisition and interpretation of appropriate clinical investigations and formulation of clinical management plans.1.5 Perform delegated clinical trial duties as above, including protocol specific tasks as part of a clinical trial where delegated by the Principle Investigator and approved by the Sponsor.1.6 Use expertise and decisionmaking skills to inform clinical reasoning fordifferentiated and undifferentiated presentations. Synthesise information from multiple sources to make appropriate, evidence based judgements and/or diagnosis.1.7 Prescribe licenced and non-licenced drugs within the capacity of non-medical prescribing, adhering to Trust policy and existing frameworks. Prescribe appropriate blood products as per Trust policy.1.8 Have advanced resuscitation skills and support the inter-professional team during and after an emergency event and support emergency scenario training.1.9 Liaise with the wider inter-professional teams (i.e. palliative care, critical care, junior Drs on call and out of hours team) regarding the management of patients under their care1.10 Accept referrals from other health care professionals and refer patients directly to other specialties within the appropriate primary, secondary and tertiary care settings.1.11 Communicate highly complex and sensitive information to patients and their significantothers, this may include diagnosis, results of scans or other investigations,management options and prognosis.1.12 Demonstrate effective communication skills, supporting patients and relatives in decision making, planning care or seeking to make positive health related lifestyle changes.1.13 Work collaboratively with an appropriate range of multi-agency and multi-professional resources, developing, maintaining and evaluating links to manage risk and issues across organisations and settings.1.14 Prepare accurate and concise records and reports, both verbal and written. Communicate with the patients referring specialist, GP and other community and hospice based services at regular intervals as appropriate.1.15 Contribute to clinical and research governance processes, including adverse incidentreporting and the investigation and the management of complaints as appropriate.1.16 Act on professional judgement about when to seek help, demonstrating criticalreflection on own practice, self-awareness, emotional intelligence, and openness to change.

Person Specification

Qualifications

Essential

  • MSc that included history taking and clinical examination of patients (or be working towards)
  • Registered General Nurse - Currently registered with the Nursing & Midwifery Council/Registered AHP
  • Teaching/ Mentorship experience.
  • Independent non-medical prescriber

Desirable

  • Advanced Life Support Course.
  • Coaching
  • Leadership qualification
  • Current GCP certificate

Experience

Essential

  • Relevant post registration experience in oncology and clinical research.
  • Evidence of Clinical Leadership
  • Evidence of negotiation/ conflict management skills
  • Experience of assessing and managing acute medical problems.
  • Experience of managing a variety of medical problems, for example: Oncology, Haematology, Acute Oncology.
  • Experience of working autonomously and as part of a team.
  • Experience in delivering teaching programmes.
  • Ability to work across professional boundaries.

Desirable

  • Experience in undertaking audit and management of change in practice related to audit results
  • Experience in nurse led research

Skills

Essential

  • Excellent communication and leadership skills: interpersonal, written and verbal.
  • Confidence to adapt to an evolving and changing service.
  • Evidence of significant involvement in change management and service development.
  • Ability to assess and manage patient risk effectively and safely.
  • Good time management, organisational skills and ability to prioritise a busy/ unpredictable workload.
  • Well developed IT skills/ word processing/ data collection/ internet skills.
  • Committed to professional development.

Desirable

  • Leadership and Management skills.
  • Innovative and motivated.
  • Ability to think strategically in relation to long-term service development.
  • Presentation skills.
  • Reflective practitioner.
  • Advanced Life Support Course

Knowledge

Essential

  • In depth knowledge of clinical research processes and all legislation and regulations associated with the clinical research
  • Knowledge of the national research agenda and implications on organisations.
  • Initiate and/or become involved in research projects in response to identified needs.
  • Disseminate results/research findings via local team and/or national/international publications.
  • Promote the shared objectives of the inter-disciplinary team by working closely to ensure that best practice is achieved utilising both Clinical Benchmarking and Essence of Care processes to achieve this.
  • Understanding of evidence based practice.
  • Working knowledge of clinical and research governance.
  • Ability to use research findings in clinical practice.
  • Knowledge of national standards and policy that inform best practice (for example: NICE/ Department of Health guidelines).
  • Appreciate the accountability associated with advanced clinical roles.

Desirable

  • Experience of policy and procedure writing.
  • Understanding of the Modernisation agenda and NHS structures.
  • Research methodologies

Other

Essential

  • Committed and flexible with shift patterns and availability.
Person Specification

Qualifications

Essential

  • MSc that included history taking and clinical examination of patients (or be working towards)
  • Registered General Nurse - Currently registered with the Nursing & Midwifery Council/Registered AHP
  • Teaching/ Mentorship experience.
  • Independent non-medical prescriber

Desirable

  • Advanced Life Support Course.
  • Coaching
  • Leadership qualification
  • Current GCP certificate

Experience

Essential

  • Relevant post registration experience in oncology and clinical research.
  • Evidence of Clinical Leadership
  • Evidence of negotiation/ conflict management skills
  • Experience of assessing and managing acute medical problems.
  • Experience of managing a variety of medical problems, for example: Oncology, Haematology, Acute Oncology.
  • Experience of working autonomously and as part of a team.
  • Experience in delivering teaching programmes.
  • Ability to work across professional boundaries.

Desirable

  • Experience in undertaking audit and management of change in practice related to audit results
  • Experience in nurse led research

Skills

Essential

  • Excellent communication and leadership skills: interpersonal, written and verbal.
  • Confidence to adapt to an evolving and changing service.
  • Evidence of significant involvement in change management and service development.
  • Ability to assess and manage patient risk effectively and safely.
  • Good time management, organisational skills and ability to prioritise a busy/ unpredictable workload.
  • Well developed IT skills/ word processing/ data collection/ internet skills.
  • Committed to professional development.

Desirable

  • Leadership and Management skills.
  • Innovative and motivated.
  • Ability to think strategically in relation to long-term service development.
  • Presentation skills.
  • Reflective practitioner.
  • Advanced Life Support Course

Knowledge

Essential

  • In depth knowledge of clinical research processes and all legislation and regulations associated with the clinical research
  • Knowledge of the national research agenda and implications on organisations.
  • Initiate and/or become involved in research projects in response to identified needs.
  • Disseminate results/research findings via local team and/or national/international publications.
  • Promote the shared objectives of the inter-disciplinary team by working closely to ensure that best practice is achieved utilising both Clinical Benchmarking and Essence of Care processes to achieve this.
  • Understanding of evidence based practice.
  • Working knowledge of clinical and research governance.
  • Ability to use research findings in clinical practice.
  • Knowledge of national standards and policy that inform best practice (for example: NICE/ Department of Health guidelines).
  • Appreciate the accountability associated with advanced clinical roles.

Desirable

  • Experience of policy and procedure writing.
  • Understanding of the Modernisation agenda and NHS structures.
  • Research methodologies

Other

Essential

  • Committed and flexible with shift patterns and availability.

Disclosure and Barring Service Check

This post is subject to the Rehabilitation of Offenders Act (Exceptions Order) 1975 and as such it will be necessary for a submission for Disclosure to be made to the Disclosure and Barring Service (formerly known as CRB) to check for any previous criminal convictions.

Certificate of Sponsorship

Applications from job seekers who require current Skilled worker sponsorship to work in the UK are welcome and will be considered alongside all other applications. For further information visit the UK Visas and Immigration website (Opens in a new tab).

From 6 April 2017, skilled worker applicants, applying for entry clearance into the UK, have had to present a criminal record certificate from each country they have resided continuously or cumulatively for 12 months or more in the past 10 years. Adult dependants (over 18 years old) are also subject to this requirement. Guidance can be found here Criminal records checks for overseas applicants (Opens in a new tab).

Additional information

Disclosure and Barring Service Check

This post is subject to the Rehabilitation of Offenders Act (Exceptions Order) 1975 and as such it will be necessary for a submission for Disclosure to be made to the Disclosure and Barring Service (formerly known as CRB) to check for any previous criminal convictions.

Certificate of Sponsorship

Applications from job seekers who require current Skilled worker sponsorship to work in the UK are welcome and will be considered alongside all other applications. For further information visit the UK Visas and Immigration website (Opens in a new tab).

From 6 April 2017, skilled worker applicants, applying for entry clearance into the UK, have had to present a criminal record certificate from each country they have resided continuously or cumulatively for 12 months or more in the past 10 years. Adult dependants (over 18 years old) are also subject to this requirement. Guidance can be found here Criminal records checks for overseas applicants (Opens in a new tab).

Employer details

Employer name

The Christie NHS FT

Address

Haematology - Q00675

Manchester

M20 4BX


Employer's website

https://www.christie.nhs.uk/ (Opens in a new tab)

Employer details

Employer name

The Christie NHS FT

Address

Haematology - Q00675

Manchester

M20 4BX


Employer's website

https://www.christie.nhs.uk/ (Opens in a new tab)

Employer contact details

For questions about the job, contact:

Lead Research Nurse

Andrea Whitmore

Andrea.whitmore@nhs.net

07880482222

Details

Date posted

13 October 2025

Pay scheme

Agenda for change

Band

Band 8a

Salary

£55,690 to £62,682 a year Per annum, Pro rata

Contract

Permanent

Working pattern

Full-time

Reference number

413-99506-RI-DA

Job locations

Haematology - Q00675

Manchester

M20 4BX


Supporting documents

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