Senior/Junior Haematology Clinical Trials Research Fellow

Job responsibilities

ORGANISATIONAL ARRANGEMENTSThis post is for 32 hours per week to provide a Clinical Fellowship within Haematology Research.

Role PurposeThe Clinical Fellowship will allow the successful candidate unique opportunities to gain experience in clinical trials and clinical management of intensively treated Haematology Oncology patients including management of patients receiving novel cellular therapies (CAR-T cell

therapy), stem cell transplantation.

DUTIES AND RESPONSIBILITIESThe medical establishment provides 18 consultants and 7 resident doctors and also Clinical Fellows and Advanced Care Practitioners (ACP).

The position is suitable for individuals who wish to gain further experience in experimental medicine & Phase I trials, including first-in-human trials.

A diverse range of clinical research trials are in progress & following training, the post holder will participate in these studies as a co-/sub-investigator. These include Phase I trials of small molecule inhibitors, combination / multi-modality Phase I trials, and trials of CAR-T and bispecific antibodies. The post holder will be involved in managing all aspects of trial patients (both in outpatient & in-patients setting), across all areas of haematological malignancy, through new patient consultation, consent & screening patients & reviewing patients at follow-up appointments.

The post holder will attend Safety Review Committee meetings (usually remotely) to discuss trial patients. This will involve close liaison with Principal Investigators, referring consultant body across the north of England and Wales & other team members. The appointee will interface with external stakeholders such as CROs & pharmaceutical sponsors.

The appointee will undertake the administrative duties associated with the care of their patients. The appointee will be encouraged to be involved in the development & planning of new studies.

The Fellow will maintain a level of continuing professional development. There is the potential to present research work & the post holder will be expected to be involved in writing papers & reviews. The post holder will also be required to undergo an annual appraisal.

The Fellow will be expected to contribute to both undergraduate & postgraduate teaching, and aspects of clinical governance & audit.

Inpatient and day unit

The Haematology Fellow will join the existing Palatine ward Haematology clinical team ensuring thatall patients across the department have optimal daily clinical cover. Working as part of the existing ward team which includes 2 Haematology ST doctors, 1 TYA Oncology Senior clinical fellow, 1 Junior Oncology fellow and 3 x ward-based IMTs who cover the 31 bedded-ward. . The haematology fellow will have a particular responsibility for supervision of patients on the new 4 inpatient bedded unit due to open early 2021 and the adjacent ambulatory care unit. The Haematology service is supported by an attending consultant, with 2 scheduled consultant ward rounds per week and daily consultant level input as required.

Outpatients

There will be an opportunity to attend the Haematology departmental weekly teaching sessions and to participate in Haematology outpatient clinics focusing on patients enrolled in clinical trials.

Person requirements

Flexible working and cross-cover with existing Palatine Ward middle grade haematology roles (Haematology Specialist Registrars and the Trust Grade post) will be a requirement within this post.

The post holder will require good communication skills in order to work effectively/collaboratively within the broader teams, but also in order to engage and build up rapport with patients and their families undergoing complex oncology/Haematology treatments. The post holder will be flexible, adaptable and communicate positively at all times. They will provide information at an appropriate level of understanding to ensure a patient and/or carer is fully informed at all stages of the pathway and will communicate with patients, families and carers with empathy and reassurance. They will need good time management/organizational skills to prioritize the patient workload.

Research, Audit and Quality Improvement

The post holder will develop knowledge of research governance, clinical governance, research ethics, and work within and comply with the principles of Good Clinical Practice (ICH GCP).

They will work to support clinical audits, report results and where necessary, to implement change. They may be required to disseminate relevant research findings to colleagues and members of the health professions via presentation and publication. They will work within and contribute to the Trusts governance processes and framework.

Continuing Professional DevelopmentThe Trust supports the requirements for continuing professional development (CPD) as laid down by the GMC and surgical colleges and is committed to providing time and financial support for these activities.

Role Planning

Period

Monday

Tuesday

Wednesday

Thursday

Friday

AM

CRF Early Phase Clinic

CRF ward round

CRF Early Phase and Haem Research Clinic

CRF ward round

Palatine Ward

8am Education Meeting

CRF ward round

Research Administration (SAE query resolution, trial safety meetings)

Haematology Day Unit

PM

New patient trials clinic (HTDU)

13:00-14.00- CTC Meeting

14.00 onwards

Ambulatory care

Clinic admin

15:00 - MDT

13:00 Trial patient planning and prioritization meeting

Ambulatory Care

Research/ audit project work.

16:00 Handover (if on call)

Qualifications

Essential

• MRCP or equivalent
• Primary medical qualification (MBBS or equivalent)
• GMC registration

Desirable

• FRCPath or equivalent
• Good Clinical Practice
• Higher degree

Research / Publications

Desirable

• Recent publications in peer-reviewed Journals

Training

Essential

• Experience in managing acutely unwell patient undergoing chemotherapy

Desirable

• ALS certificate in date
• Evidence of clinical leadership skills

Experience

Essential

• Experience managing Haematology inpatients
• Interest and documented experience in Clinical Audit

Desirable

• Conference presentations

Teaching

Essential

• Documented experience of ward based peer to peer teaching or teaching of undergraduates

Desirable

• Teaching qualification

Personal Skills

Essential

• Excellent written and oral communication skills
• Flexibility, commitment and compatibility with colleagues and multidisciplinary staff in the department
• Reliable work record

Motivation

Essential

• Committed to career pathway in Haematology
• Aspiration to develop extensive clinical experience in Haematology Oncology including novel high intensity therapies

Disclosure and Barring Service Check

This post is subject to the Rehabilitation of Offenders Act (Exceptions Order) 1975 and as such it will be necessary for a submission for Disclosure to be made to the Disclosure and Barring Service (formerly known as CRB) to check for any previous criminal convictions.

UK Registration

Applicants must have current UK professional registration. For further information please see NHS Careers website (opens in a new window).