Oxford University Hospitals NHS Foundation Trust

Deputy Accountable Pharmacist for Clinical Trials Aseptic Services

The closing date is 22 May 2025

Job summary

Proposed interview date - Thursday 05/06

Hi I'm Michelle, Senior Pharmacist Manager and we are looking for a passionate and dynamicpharmacist to join our Pharmacy Clinical Trials team, as the Deputy Aseptic Unit Manager for our unique and well-established facility. The role is dedicated to clinical trials and you will work as part of the wider Pharmacy Clinical Trials team. In your new role, you will have the opportunity to use your knowledge and experience of working in aseptics in UK and build on this to deliver a range of aseptically dispensed clinical trial medicines. Oxford University Hospitals NHS trust has a large portfolio of studies supporting all clinical specialities and you will work with a range of research and pharmacy staff to set-up new studies, provide aseptically prepared doses for open trials and expert advice. Are you passionate about learning and helping to deliver new novel treatments including ATMPs? These are a big part of our remit and your interest to deliver, train and further develop this service will be part of your role. Not done this before? You can still apply for role as we can support your learning and training for ATMPs, as we have already developed the service.We have strong team values and work together to deliver a timely and efficient service through kindness and support for one another.

Main duties of the job

The main responsibilities of this role are to be the Deputy Accountable Pharmacist for the Clinical Trials Aseptic Services Unit, and the Clinical Trials Pharmacy lead for Advanced Therapy Medicinal Products (ATMPs).

Working closely with the Accountable Pharmacist, the postholder will be responsible for the management, leadership and co-ordination of a Clinical Trials Aseptic Service and the provision of selected high risk injectable medicines to all Divisions within the Trust. This will require providing information, advice and liaising with researchers and external partners outside of OUH.

Working with the Accountable Pharmacist, and the Lead Pharmacist for Clinical Trials the postholder will work to implement technical, professional, best practice and regulatory requirements for the preparation and supply of Advanced Therapy Investigational Medicinal Products (ATIMPs)

About us

Oxford University Hospitals NHS Foundation Trust is one of the largest NHS teaching trusts in the country. It provides a wide range of general and specialist clinical services and is a base for medical education, training and research. The Trust comprises four hospitals - the John Radcliffe Hospital, Churchill Hospital and Nuffield Orthopaedic Centre in Headington and the Horton General Hospital in Banbury. For more information on OUH please view OUH At a Glance by OUHospitals - Issuu

Our values, standards and behaviours define the quality of clinical care we offer and the professional relationships we make with our patients, colleagues and the wider community.

We call this Delivering Compassionate Excellence and its focus is on our values of compassion, respect, learning, delivery, improvement and excellence.

Date posted

08 May 2025

Pay scheme

Agenda for change

Band

Band 7

Salary

£46,148 to £60,504 a year per annum pro rata

Contract

Permanent

Working pattern

Full-time, Flexible working

Reference number

321-CORP-7075538-B8a

Job locations

Churchill Hospital

Old Road Headington

Oxford

OX3 7LE

Job description

Job responsibilities

Clinical Trials Aseptic ServicesTo deputise for the Accountable Pharmacist responsible under the Section 10 exemption of the Medicines Act and in accordance with current guidance and best practice, as detailed but not limited to those set out, in Quality Assurance of Aseptic Preparation Services (QAAPs) handbook.Alongside the Accountable Pharmacist, and the Aseptic Services Manager to be responsible for the management, leadership and co-ordination of a Clinical Trials Aseptic Service and the provision of selected high risk injectable medicines to all Divisions within the Trust.

To be responsible for the release and distribution of aseptically prepared products from CTAS and the training of authorised pharmacists.

To manage and provide expert advice to support to Aseptic Unit Manager to ensure that the facility and staff deliver to QAAPs and ICH-GCP standards for dispensing aseptically prepared doses.

To be responsible for reviewing the impact of changes to QAAPS/GMP standards and implementing change where required.

To provide cost-effective delivery of high quality aseptic pharmaceuticals, which are fit for their intended purpose to patients of the Trust, and other external customers of the service.

To participate in identifying and implementing initiatives as appropriate to reduce the financial costs and the environmental impact of CTAS service, through QI approach.

To set-up new trials that require aseptic preparation of doses in accordance with local procedures and GMP and ICH-GCP regulations, and review trials that have been set-up by pharmacy clinical trials colleagues for final Pharmacy approval.

To provide expert advice on matters relating to the use of injectable medicines and specialist technical pharmacy knowledge to all Divisions within the Trust, as well as to the University of Oxford research teams.

Alongside the Accountable Pharmacist assess IMPs and other injectable products for the most suitable preparation area.

Be responsible for the writing, amending and reviewing of worksheets.

Initiates, advises and contributes to research and development of new aseptic preparation methods (including the introduction of new technology and novel products) of work; to publish findings as appropriate.

ATMPsTo work with the Accountable Pharmacist to establish best practice for the handling of ATMPs in the aseptic unit or a biological safety cabinet. To support commissioning of any new equipment and facilities.

Work with the clinical areas and the local biological safety officers to establish best practice for the handling of ATIMPs in the clinical areas.

Alongside the Consultant Pharmacist for cancer and ATMPs act as the subject matter expert for ATMPs in the Trust.

To set-up new ATMP trials in accordance with local procedures and GMP, HSE and ICH-GCP regulations, and review trials that have been set-up by pharmacy clinical trials colleagues for final Pharmacy approval.

Work with the Consultant Pharmacists and Divisional Lead Pharmacists to ensure appropriate governance arrangements are in place for the prescribing, handling and administration of ATMPs.

ManagementTo line manage staff and undertake all aspects such as appraisals, manage leave, training.

As senior member of the team, manage, support and supervision the team and support effective communication and be pro-active.

To ensure own professional development, registration, annual appraisal and maintain core training.

Uphold the values of the trust.

If you are interested in this role but don't have the required experience or knowledge, then we can offer as a progression post from B7 to B8a. Please get in touch for an informal chat if you have any questions.