Job summary
Clinical Research Fellow- UCL/UCLH Institute of Neurology, Ataxia Centre
Applications are invited for a Clinical Research Fellow in the Ataxia Centre, UCL/UCLH Department of Neuroscience and Neurogenetics, UCL Institute of Neurology, under the supervision of Prof Paola Giunti. The post offers an exciting opportunity to gain experience of translational research as part of an internationally recognised multi-disciplinary team
Main duties of the job
The postholder will be an essential member of the research team at the Ataxia Centre, providing clinical and research input into the Centre's research programme into Ataxia and will work closely with the Principal Investigators (PIs), Clinical Research Fellows and Clinical Trials nurses. Their primary role will be as sub-investigator in clinical drug trial: A phase 1/2a, open-label trial to investigate the safety, tolerability, pharmacokinetics, and pharmacodynamics of multiple ascending doses of intrathecally administered VO659 in participants with spinocerebellar ataxia types 1, 3. assessing the safety of this novel Antisense oligonucleotide(ASO) treatment in patients with these rare diseases. He/she will also have the opportunity to participate in current basic and observational research including longitudinal studies of dominant and recessive ataxias and at-risk groups and healthy volunteers to identify reliable biomarkers of disease and develop new therapeutic targets. The postholder will gain extensive experience in the set up and execution of clinical trials and laboratory based / translational research. They will also be involved in the clinical activity of the Ataxia clinics and the multidisciplinary meeting.
About us
University College London Hospitals NHS Foundation Trust (UCLH) is one of the most complex NHS trusts in the UK, serving a large and diverse population. We provide academically led acute and specialist services, to people from the local area, from throughout the United Kingdom and overseas. Our vision is to deliver top-quality patient care, excellent education, and world-class research.
We provide first-class acute and specialist services across eight sites:
- University College Hospital (incorporating the Elizabeth Garrett Anderson Wing)
- National Hospital for Neurology and Neurosurgery
- Royal National ENT and Eastman Dental Hospitals
- University College Hospital Grafton Way Building
- Royal London Hospital for Integrated Medicine
- University College Hospital Macmillan Cancer Centre
- The Hospital for Tropical Diseases
- University College Hospital at Westmoreland Street
We are dedicated to the diagnosis and treatment of many complex illnesses. UCLH specialises in women's health and the treatment of cancer, infection, neurological, gastrointestinal and oral disease. It has world class support services including critical care, imaging, nuclear medicine and pathology.
At UCLH, we have a real 'One Team' ethos, and our values - safety, kindness, teamwork and improving, are central to the way we work. This is supported by our staff, who voted us as the #1 NHS Acute Trust to work for in the whole of England.
Job description
Job responsibilities
Applicants should have a medical degree and full GMC Registration, and have previous experience in neurology, or general medicine and excellent skill in performing lumbar puncture. The successful candidate will have good inter-personal skills, the ability to work co-operatively in a multidisciplinary setting and the ability to demonstrate a record of academic clinical excellence.
We offer our permanent staff an interest free season ticket loan for travel, a subsidised social club including gym, a library for staff to use, free independent and confidential support for all staff, large retail discounts, car leasing scheme and on-site accommodation to name a few.
Please note that if you have not heard from us within 3 weeks of the closing date of the advert to assume that you have not been shortlisted on this occasion.
Job description
Job responsibilities
Applicants should have a medical degree and full GMC Registration, and have previous experience in neurology, or general medicine and excellent skill in performing lumbar puncture. The successful candidate will have good inter-personal skills, the ability to work co-operatively in a multidisciplinary setting and the ability to demonstrate a record of academic clinical excellence.
We offer our permanent staff an interest free season ticket loan for travel, a subsidised social club including gym, a library for staff to use, free independent and confidential support for all staff, large retail discounts, car leasing scheme and on-site accommodation to name a few.
Please note that if you have not heard from us within 3 weeks of the closing date of the advert to assume that you have not been shortlisted on this occasion.
Person Specification
Knowledge and Qualifications
Essential
- Educated to degree level (Medical Doctor)
- Full GMC registration MRCP, or equivalent
- Experience in neurology, psychiatry or general medicine
Desirable
- Proven knowledge of GCP guidelines
- Completed/working towards degree in the speciality or related field
Communication
Essential
- Computer literacy
- Proven ability to communicate effectively in writing
- Proven ability to communicate effectively verbally
Desirable
- Medical or scientific writing skills
- Aptitude for data analysis
Skills and Abilities
Essential
- Previous experience in audit and evaluation
- Experience of phlebotomy, cannulation, and management of central lines,
- Experience of lumbar puncture
- Ability to work under own initiative
- Able to work autonomously with minimal supervision
- Able to work across organisational and professional boundaries
Desirable
- Experience of formal/informal teaching of patients and staff
- Experience of formal/informal teaching of patients and staff
- Experience in performing skin biopsies
Experience
Essential
- Clinical research experience/ understanding of research methodology
- Experience of genetics and/or neurology
- Experience in delivering evidence-based practice.
- Experience of explaining complex concepts to patients in a clear and simplified manner with a very high level of consideration & care for patients, their carers and families
- Experience of working in the NHS
- Experience of administrating neuropsychological/cognitive assessments
- Experience of formal/informal teaching of patients and staff
- Experience of acting as a patient advocate
Desirable
- Experience of working with patients with neurodegenerative disorders
Person Specification
Knowledge and Qualifications
Essential
- Educated to degree level (Medical Doctor)
- Full GMC registration MRCP, or equivalent
- Experience in neurology, psychiatry or general medicine
Desirable
- Proven knowledge of GCP guidelines
- Completed/working towards degree in the speciality or related field
Communication
Essential
- Computer literacy
- Proven ability to communicate effectively in writing
- Proven ability to communicate effectively verbally
Desirable
- Medical or scientific writing skills
- Aptitude for data analysis
Skills and Abilities
Essential
- Previous experience in audit and evaluation
- Experience of phlebotomy, cannulation, and management of central lines,
- Experience of lumbar puncture
- Ability to work under own initiative
- Able to work autonomously with minimal supervision
- Able to work across organisational and professional boundaries
Desirable
- Experience of formal/informal teaching of patients and staff
- Experience of formal/informal teaching of patients and staff
- Experience in performing skin biopsies
Experience
Essential
- Clinical research experience/ understanding of research methodology
- Experience of genetics and/or neurology
- Experience in delivering evidence-based practice.
- Experience of explaining complex concepts to patients in a clear and simplified manner with a very high level of consideration & care for patients, their carers and families
- Experience of working in the NHS
- Experience of administrating neuropsychological/cognitive assessments
- Experience of formal/informal teaching of patients and staff
- Experience of acting as a patient advocate
Desirable
- Experience of working with patients with neurodegenerative disorders
Disclosure and Barring Service Check
This post is subject to the Rehabilitation of Offenders Act (Exceptions Order) 1975 and as such it will be necessary for a submission for Disclosure to be made to the Disclosure and Barring Service (formerly known as CRB) to check for any previous criminal convictions.
Applications from job seekers who require current Skilled worker sponsorship to work in the UK are welcome and will be considered alongside all other applications. For further information visit the UK Visas and Immigration website (Opens in a new tab).
From 6 April 2017, skilled worker applicants, applying for entry clearance into the UK, have had to present a criminal record certificate from each country they have resided continuously or cumulatively for 12 months or more in the past 10 years. Adult dependants (over 18 years old) are also subject to this requirement. Guidance can be found here Criminal records checks for overseas applicants (Opens in a new tab).
UK Registration
Applicants must have current UK professional registration. For further information please see
NHS Careers website (opens in a new window).
Additional information
Disclosure and Barring Service Check
This post is subject to the Rehabilitation of Offenders Act (Exceptions Order) 1975 and as such it will be necessary for a submission for Disclosure to be made to the Disclosure and Barring Service (formerly known as CRB) to check for any previous criminal convictions.
Applications from job seekers who require current Skilled worker sponsorship to work in the UK are welcome and will be considered alongside all other applications. For further information visit the UK Visas and Immigration website (Opens in a new tab).
From 6 April 2017, skilled worker applicants, applying for entry clearance into the UK, have had to present a criminal record certificate from each country they have resided continuously or cumulatively for 12 months or more in the past 10 years. Adult dependants (over 18 years old) are also subject to this requirement. Guidance can be found here Criminal records checks for overseas applicants (Opens in a new tab).
UK Registration
Applicants must have current UK professional registration. For further information please see
NHS Careers website (opens in a new window).
