Leeds Teaching Hospitals

Advanced Biomedical Scientist - Inherited Metabolic Disease

The closing date is 22 August 2025

Job summary

Expected Shortlisting Date

21/08/2025

Planned Interview Date

04/09/2025

**No Night Shifts**

We currently have a vacancy for a motivated and enthusiastic individual to work as an advanced biomedical scientist (AFC band 7) in the Biochemical Genetics laboratory. This role is for a BMS/technical lead for the IMD section in conjuction with another Band 7 BMS. The post is full time, working from 8.30am to 5pm Monday to Friday, although some flexibility may be possible within the needs of the service. Occasional Saturday morning shifts will be required to support the neonatal screening services after completion of training.

We invite applications from enthusiastic and committed individuals with proven experience working within a busy biochemistry laboratory environment.

The Biochemical Genetics laboratory supports the West Yorkshire region and receives samples from many other labs nationally. The laboratory performs a wide range of assays for the diagnosis and monitoring of inherited metabolic diseases including amino acid analysis, urine organic acids and acylcarnitines, as well as ultra-specialist tests including creatine metabolites, white cell cystine and purine and pyrimidine analysis. This is reliant on techniques such as LC-MS/MS, GC-MS, anion exchange-HPLC, thin layer chromatography and more.

Main duties of the job

As a biomedical scientist in biochemical genetics you will be a fully competent member of the department.

Working as part of a team within your lab and liaising closely with clinical scientists and the wider pathology department.

Performing a wide range of specialist investigations with the ability for clinical interpretation of (particularly annotation of urine organic acid and amino acid chromatograms) and managing specialist analysis.

Working towards the provision of an accurate and timely service for patients. You will be expected to apply professional judgements and specialist skills to technically complex and sometimes difficult situations with the support of Clinical Scientists.

Within the team you will organise the tasks of support workers and BMSs and provide training and support to all staff and colleagues working in your section.

You will be required to communicate highly complex information, often related to patient management and care, to colleagues, healthcare staff and other organisations.

Preparing team rosters and arranging regular meetings within your section.

Candidates will be HCPC registered biomedical scientists with demonstrable post registration experience. Specific experience in the biochemical diagnosis and monitoring of inherited metabolic disease and the use of LC-MS and GC-MS would be advantageous but is not essential and full training will be provided.

About us

An exciting opportunity has arisen to work in our new facility, the Centre for Laboratory Medicine, at the St Jamess University Hospital site in Leeds.

We currently have a vacancy for a motivated and enthusiastic individual to work as an advanced biomedical scientist (AFC band 7) in the Biochemical Genetics laboratory. This role is for a BMS/technical lead for the IMD section in conjuction with another Band 7 BMS. The post is full time, working from 8.30am to 5pm Monday to Friday, although some flexibility may be possible within the needs of the service. Occasional Saturday morning shifts will be required to support the neonatal screening services after completion of training.

Leeds Teaching Hospitals is committed to our process of redeploying 'at risk' members of our existing workforce to new roles. As such, all our job adverts are subject to this policy and we reserve the right to close, delay or remove adverts while this process is completed. If you do experience a delay in the shortlisting stage of the recruitment cycle, please bear with us while this process is completed, and contact the named contact if you have any questions.

Details

Date posted

01 August 2025

Pay scheme

Agenda for change

Band

Band 7

Salary

£47,810 to £54,710 a year

Contract

Permanent

Working pattern

Full-time

Reference number

C9298-PATH-464

Job locations

St. James's University Hospital

Beckett Street

Leeds

LS9 7TF


Job description

Job responsibilities

An exciting opportunity has arisen to work in our new facility, the Centre for Laboratory Medicine, at the St Jamess University Hospital site in Leeds.

We currently have a vacancy for a motivated and enthusiastic individual to work as an advanced biomedical scientist (AFC band 7) in the Biochemical Genetics laboratory. This role is for a BMS/technical lead for the IMD section in conjuction with another Band 7 BMS. The post is full time, working from 8.30am to 5pm Monday to Friday, although some flexibility may be possible within the needs of the service. Occasional Saturday morning shifts will be required to support the neonatal screening services after completion of training.

We invite applications from enthusiastic and committed individuals with proven experience working within a busy biochemistry laboratory environment. Applications from candidates with an interest in inherited metabolic diseases and/or assay development would be particularly welcome. The successful applicant will be an excellent team player and will be able to demonstrate a strong work ethic.

The Biochemical Genetics laboratory supports the West Yorkshire region and receives samples from many other labs nationally. The laboratory performs a wide range of assays for the diagnosis and monitoring of inherited metabolic diseases including amino acid analysis, urine organic acids and acylcarnitines, as well as ultra-specialist tests including creatine metabolites, white cell cystine and purine and pyrimidine analysis. This is reliant on techniques such as LC-MS/MS, GC-MS, anion exchange-HPLC, thin layer chromatography and more. As a department we aim to provide a consistently high quality and professional service to all our users. The successful candidate will join our team in the delivery of this service and be involved in day-to-day management of the laboratory, supporting lab testing, attending meetings and all aspects of lab quality.

Candidates will be HCPC registered biomedical scientists with demonstrable post registration experience. Specific experience in the biochemical diagnosis and monitoring of inherited metabolic disease and the use of LC-MS and GC-MS would be advantageous but is not essential and full training will be provided.

See attached job description for expectations for this role. In general, you will be responsible for the day-to-day supervision of the biochemical genetics lab, alongside another band 7 BMS and support from clinical scientists, with responsibility for ensuring that assays are completed in a timely manner. You will also have a role in troubleshooting problem equipment and ensuring high quality results. A large part of the role will involve annotation of chromatograms for urine organic acid chromatograms and amino acids.

Able to work well as part of a team. Able to work on own initiative. Excellent ability to communicate.

For more information or to arrange an informal visit, please contact Roger Bramley (Principal Clinical Scientist) 0113 20 66590 (roger.bramley2@nhs.net), Robert Barski (Consultant Clinical Scientist) 0113 2066861 (robert.barski@nhs.net) or Nayab Nawaz (Operational Lead) on 0113 2066860 (nayab.nawaz@nhs.net).

Job description

Job responsibilities

An exciting opportunity has arisen to work in our new facility, the Centre for Laboratory Medicine, at the St Jamess University Hospital site in Leeds.

We currently have a vacancy for a motivated and enthusiastic individual to work as an advanced biomedical scientist (AFC band 7) in the Biochemical Genetics laboratory. This role is for a BMS/technical lead for the IMD section in conjuction with another Band 7 BMS. The post is full time, working from 8.30am to 5pm Monday to Friday, although some flexibility may be possible within the needs of the service. Occasional Saturday morning shifts will be required to support the neonatal screening services after completion of training.

We invite applications from enthusiastic and committed individuals with proven experience working within a busy biochemistry laboratory environment. Applications from candidates with an interest in inherited metabolic diseases and/or assay development would be particularly welcome. The successful applicant will be an excellent team player and will be able to demonstrate a strong work ethic.

The Biochemical Genetics laboratory supports the West Yorkshire region and receives samples from many other labs nationally. The laboratory performs a wide range of assays for the diagnosis and monitoring of inherited metabolic diseases including amino acid analysis, urine organic acids and acylcarnitines, as well as ultra-specialist tests including creatine metabolites, white cell cystine and purine and pyrimidine analysis. This is reliant on techniques such as LC-MS/MS, GC-MS, anion exchange-HPLC, thin layer chromatography and more. As a department we aim to provide a consistently high quality and professional service to all our users. The successful candidate will join our team in the delivery of this service and be involved in day-to-day management of the laboratory, supporting lab testing, attending meetings and all aspects of lab quality.

Candidates will be HCPC registered biomedical scientists with demonstrable post registration experience. Specific experience in the biochemical diagnosis and monitoring of inherited metabolic disease and the use of LC-MS and GC-MS would be advantageous but is not essential and full training will be provided.

See attached job description for expectations for this role. In general, you will be responsible for the day-to-day supervision of the biochemical genetics lab, alongside another band 7 BMS and support from clinical scientists, with responsibility for ensuring that assays are completed in a timely manner. You will also have a role in troubleshooting problem equipment and ensuring high quality results. A large part of the role will involve annotation of chromatograms for urine organic acid chromatograms and amino acids.

Able to work well as part of a team. Able to work on own initiative. Excellent ability to communicate.

For more information or to arrange an informal visit, please contact Roger Bramley (Principal Clinical Scientist) 0113 20 66590 (roger.bramley2@nhs.net), Robert Barski (Consultant Clinical Scientist) 0113 2066861 (robert.barski@nhs.net) or Nayab Nawaz (Operational Lead) on 0113 2066860 (nayab.nawaz@nhs.net).

Person Specification

Skills & behaviours

Essential

  • Evidence of multi-tasking ability, such as performing a combination of laboratory work
  • Update of documentation like SOPs
  • Following the ISO 15189 accreditation.
  • Able to work well as part of a team.
  • Excellent ability to communicate.
  • Able to work on own initiative.

Qualifications

Essential

  • Masters degree and or higher specialist portfolio

Desirable

  • Completion of a management course
  • Experience within a specialist services laboratory would be an advantage
  • Use of our specialist techniques would be preferred

Experience

Essential

  • Experience within a Biochemistry lab for a minimum of 2 years
  • successfully managing staff
  • Supporting training

Desirable

  • Use of complex equipment such as LC-MS/MS, GC-MS or similar
  • Experience of annotating organic acids/amino acids, assay interpretation
  • managing high-throughput specialised assays
  • Experience in troubleshooting and problem-solving.
  • Experience in using Q-pulse, Winpath and NPEx.
Person Specification

Skills & behaviours

Essential

  • Evidence of multi-tasking ability, such as performing a combination of laboratory work
  • Update of documentation like SOPs
  • Following the ISO 15189 accreditation.
  • Able to work well as part of a team.
  • Excellent ability to communicate.
  • Able to work on own initiative.

Qualifications

Essential

  • Masters degree and or higher specialist portfolio

Desirable

  • Completion of a management course
  • Experience within a specialist services laboratory would be an advantage
  • Use of our specialist techniques would be preferred

Experience

Essential

  • Experience within a Biochemistry lab for a minimum of 2 years
  • successfully managing staff
  • Supporting training

Desirable

  • Use of complex equipment such as LC-MS/MS, GC-MS or similar
  • Experience of annotating organic acids/amino acids, assay interpretation
  • managing high-throughput specialised assays
  • Experience in troubleshooting and problem-solving.
  • Experience in using Q-pulse, Winpath and NPEx.

Disclosure and Barring Service Check

This post is subject to the Rehabilitation of Offenders Act (Exceptions Order) 1975 and as such it will be necessary for a submission for Disclosure to be made to the Disclosure and Barring Service (formerly known as CRB) to check for any previous criminal convictions.

Certificate of Sponsorship

Applications from job seekers who require current Skilled worker sponsorship to work in the UK are welcome and will be considered alongside all other applications. For further information visit the UK Visas and Immigration website (Opens in a new tab).

From 6 April 2017, skilled worker applicants, applying for entry clearance into the UK, have had to present a criminal record certificate from each country they have resided continuously or cumulatively for 12 months or more in the past 10 years. Adult dependants (over 18 years old) are also subject to this requirement. Guidance can be found here Criminal records checks for overseas applicants (Opens in a new tab).

Additional information

Disclosure and Barring Service Check

This post is subject to the Rehabilitation of Offenders Act (Exceptions Order) 1975 and as such it will be necessary for a submission for Disclosure to be made to the Disclosure and Barring Service (formerly known as CRB) to check for any previous criminal convictions.

Certificate of Sponsorship

Applications from job seekers who require current Skilled worker sponsorship to work in the UK are welcome and will be considered alongside all other applications. For further information visit the UK Visas and Immigration website (Opens in a new tab).

From 6 April 2017, skilled worker applicants, applying for entry clearance into the UK, have had to present a criminal record certificate from each country they have resided continuously or cumulatively for 12 months or more in the past 10 years. Adult dependants (over 18 years old) are also subject to this requirement. Guidance can be found here Criminal records checks for overseas applicants (Opens in a new tab).

Employer details

Employer name

Leeds Teaching Hospitals

Address

St. James's University Hospital

Beckett Street

Leeds

LS9 7TF


Employer's website

https://www.leedsth.nhs.uk/ (Opens in a new tab)


Employer details

Employer name

Leeds Teaching Hospitals

Address

St. James's University Hospital

Beckett Street

Leeds

LS9 7TF


Employer's website

https://www.leedsth.nhs.uk/ (Opens in a new tab)


Employer contact details

For questions about the job, contact:

Principle Clinical Scientist

Roger Bramley

Roger.Bramley2@nhs.net

Details

Date posted

01 August 2025

Pay scheme

Agenda for change

Band

Band 7

Salary

£47,810 to £54,710 a year

Contract

Permanent

Working pattern

Full-time

Reference number

C9298-PATH-464

Job locations

St. James's University Hospital

Beckett Street

Leeds

LS9 7TF


Supporting documents

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