Job summary
Quality Control North West Liverpool is an NHS regional specialist department responsible for providing a pharmaceutical testing service to NHS and non-NHS clients. The laboratories in central Liverpool are modern and well equipped, and are regulated by the MHRA to Good Manufacturing Practice, and accredited by UKAS to ISO17025.
The Chemistry section is looking to appoint a highly motivated individual, educated to B.Sc. level in chemistry, biochemistry or a related science subject, with knowledge of a broad range of analytical techniques, the ability to record data clearly and accurately and to be able to work with and without direct supervision.
We have one permanent role and also one 12 month fixed term vacancy available to support additional projects.
Main duties of the job
As well as undertaking routine testing of pharmaceuticals preparations, the role will primarily involve project work, including method development, stability and comparative studies of pharmaceutical preparations. Stability studies are carried out on small and large molecule pharmaceutical preparations, with the laboratory acting as a specialist centre for studies on compounded mAb preparations. Techniques used include HPLC, UV, sub-visible particles and CE.
About us
Liverpool University Hospitals NHS Foundation Trust comprises Aintree University Hospital, Broadgreen Hospital & Royal Liverpool University Hospital.
We are part of NHS University Hospitals of Liverpool Group, formed on 1 Nov 2024 from the coming together of LUHFT and Liverpool Women's NHS Foundation Trust. The Group was born from a shared aim to improve the care we provide our patients.
UHLG is one of the largest employers in the region, with over 16,800 colleagues dedicated to caring for our communities - from birth and beyond.
For the 630,000 people across Merseyside, we are their local NHS. We provide general and emergency hospital care, alongside highly specialised regional services for more than two million people in the North West.
Aintree University Hospital is the single receiving site for adult major trauma patients in Cheshire and Merseyside and hosts a number of regional services including an award-winning stroke facility. Broadgreen Hospital is home to elective surgical, diagnostic and treatment services, together with specialist patient rehabilitation. Liverpool Women's Hospital specialises in the health of women and babies, delivering over 7,200 babies in the UK's largest single site maternity hospital each year. The Royal Liverpool University Hospital is the largest hospital in the country to provide inpatients with 100% single bedrooms and focuses on complex planned care and specialist services.
For roles at Liverpool Women's, visit their careers page.
Job description
Job responsibilities
To assist the Section Heads (Chemistry & Biochemistry) in maintaining a fully documented and validated scheme for the work of the chemistry laboratory. This shall include validation and monitoring of processes and techniques and collaborating with other senior staff to update systems and practices.
To assist in the development and validation of analytical methods for the testing and the development of pharmaceutical products including new generation large molecule drug formulations. To undertake such projects and help prepare high quality reports for QCNW clients.
To carry out routine but often complex chemical and biochemical analyses on raw materials, in-process samples and finished pharmaceutical products and enter sample details into the laboratory information system.
To communicate difficulties to senior staff in order to minimise delays and ensure timely and appropriate testing of samples.
To ensure all work undertaken is correctly and accurately recorded to ensure validity and traceability of data for audit purposes.
To work at all times in accordance with the requirements of the departmental Quality Manual, Good Laboratory Practice and ISO17025. All testing must be performed in accordance with established procedures to assess compliance with approved specifications.
To help maintain and improve computer information systems used within the laboratory.
To help maintain the laboratories Quality System and associated documentation.
To perform equipment calibration checks and maintenance as directed by laboratory procedures.
To help maintain the laboratory environment in an appropriate condition including the safe disposal of laboratory waste.
To participate in Section and Departmental staff meetings
To communicate with other team members so as to ensure the efficient use of equipment and the timely testing of samples.
For full details, please refer to the attached job description
Job description
Job responsibilities
To assist the Section Heads (Chemistry & Biochemistry) in maintaining a fully documented and validated scheme for the work of the chemistry laboratory. This shall include validation and monitoring of processes and techniques and collaborating with other senior staff to update systems and practices.
To assist in the development and validation of analytical methods for the testing and the development of pharmaceutical products including new generation large molecule drug formulations. To undertake such projects and help prepare high quality reports for QCNW clients.
To carry out routine but often complex chemical and biochemical analyses on raw materials, in-process samples and finished pharmaceutical products and enter sample details into the laboratory information system.
To communicate difficulties to senior staff in order to minimise delays and ensure timely and appropriate testing of samples.
To ensure all work undertaken is correctly and accurately recorded to ensure validity and traceability of data for audit purposes.
To work at all times in accordance with the requirements of the departmental Quality Manual, Good Laboratory Practice and ISO17025. All testing must be performed in accordance with established procedures to assess compliance with approved specifications.
To help maintain and improve computer information systems used within the laboratory.
To help maintain the laboratories Quality System and associated documentation.
To perform equipment calibration checks and maintenance as directed by laboratory procedures.
To help maintain the laboratory environment in an appropriate condition including the safe disposal of laboratory waste.
To participate in Section and Departmental staff meetings
To communicate with other team members so as to ensure the efficient use of equipment and the timely testing of samples.
For full details, please refer to the attached job description
Person Specification
Qualifications
Essential
- Minimum Qualification: Degree (BSc) in Chemistry, Biochemistry or in a related Pharmaceutical Science'
Experience
Essential
- Knowledge of broad range of analytical techniques
- Relevant analytical experience
- Knowledge of principles of GLP, laboratory H&S and COSHH
Desirable
- Experience in working in a laboratory operating to similar standards of GLP/UKAS
- Familiarity with pharmacopeial testing.
- IT / keyboard skills
Skills
Essential
- Ability to record data clearly and accurately
- High standard of report writing / presentation
- Good team player
- Good communication skills (verbal and written)
- Excellent manual dexterity
- A flexible approach to work and change
- Good IT skills and knowledge
- Able to work both with and without direct supervision
- Well motivated, with desire to achieve excellence in all work situations
Other
Essential
- Interest in pharmaceutical analysis
Person Specification
Qualifications
Essential
- Minimum Qualification: Degree (BSc) in Chemistry, Biochemistry or in a related Pharmaceutical Science'
Experience
Essential
- Knowledge of broad range of analytical techniques
- Relevant analytical experience
- Knowledge of principles of GLP, laboratory H&S and COSHH
Desirable
- Experience in working in a laboratory operating to similar standards of GLP/UKAS
- Familiarity with pharmacopeial testing.
- IT / keyboard skills
Skills
Essential
- Ability to record data clearly and accurately
- High standard of report writing / presentation
- Good team player
- Good communication skills (verbal and written)
- Excellent manual dexterity
- A flexible approach to work and change
- Good IT skills and knowledge
- Able to work both with and without direct supervision
- Well motivated, with desire to achieve excellence in all work situations
Other
Essential
- Interest in pharmaceutical analysis
Disclosure and Barring Service Check
This post is subject to the Rehabilitation of Offenders Act (Exceptions Order) 1975 and as such it will be necessary for a submission for Disclosure to be made to the Disclosure and Barring Service (formerly known as CRB) to check for any previous criminal convictions.
Applications from job seekers who require current Skilled worker sponsorship to work in the UK are welcome and will be considered alongside all other applications. For further information visit the UK Visas and Immigration website (Opens in a new tab).
From 6 April 2017, skilled worker applicants, applying for entry clearance into the UK, have had to present a criminal record certificate from each country they have resided continuously or cumulatively for 12 months or more in the past 10 years. Adult dependants (over 18 years old) are also subject to this requirement. Guidance can be found here Criminal records checks for overseas applicants (Opens in a new tab).
Additional information
Disclosure and Barring Service Check
This post is subject to the Rehabilitation of Offenders Act (Exceptions Order) 1975 and as such it will be necessary for a submission for Disclosure to be made to the Disclosure and Barring Service (formerly known as CRB) to check for any previous criminal convictions.
Applications from job seekers who require current Skilled worker sponsorship to work in the UK are welcome and will be considered alongside all other applications. For further information visit the UK Visas and Immigration website (Opens in a new tab).
From 6 April 2017, skilled worker applicants, applying for entry clearance into the UK, have had to present a criminal record certificate from each country they have resided continuously or cumulatively for 12 months or more in the past 10 years. Adult dependants (over 18 years old) are also subject to this requirement. Guidance can be found here Criminal records checks for overseas applicants (Opens in a new tab).
