Job summary
The Sarcoma Unit is seeking maternity cover for our Tissue Manager position. This role is responsible for our translational projects carried out between the Royal Marsden Sarcoma Unit and The Institute of Cancer Research. The Tissue Manager will be responsible for the oversight and running of the Sarcoma Unit EHE Biobank, GIST UK biobank and assigned translational sponsored studies. You must be educated to degree level with experience in the application of the Human Tissue Act and regulatory compliance and policies governing clinical research including GCP. Experience of specimen handling, working on translational studies, excellent organizational skills and the ability to make and sustain good working relationships with staff at all levels is required. Prior experience in working in clinical research within the NHS or University is essential.
To make an informal query please contact Stephanie Elston, stephanie.elston@rmh.nhs.uk.
Main duties of the job
The Tissue Manager will be responsible for the management and recruitment of the EHE Biobank and they will assist the Senior Clinical Trials Manager in oversight of the RM/ICR Sponsored translational studies with a focus on EHE studies. This post will be responsible for liaising with a variety of staff throughout the RMHNHST and ICR, and will have a close working relationship with the other members of the Sarcoma Team.
About us
The Royal Marsden NHS Foundation Trust is a world-leading cancer centre. Our role is to offer our patients the best cancer care available anywhere in the world, and to continue to make a global contribution to finding better ways of diagnosing and treating cancer. We employ over 4,500 staff in a diverse range of careers including nursing, medical, science, radiography, pharmacy, occupational therapy, finance and administrative services. We have two hospitals - one in Chelsea, London, and one in Sutton, Surrey - as well as a Medical Daycare Unit in Kingston Hospital.
At The Royal Marsden, we deal with cancer every day, so we understand how valuable life is. When people entrust their lives to us, they have the right to demand the very best. That's why the pursuit of excellence lies at the heart of everything we do.
At the heart of the hospital is our dedicated team. We offer a stimulating and dynamic working environment, a wide range of staff benefits, learning and development opportunities and clear career pathways. There are opportunities to work flexibly across a range of areas and specialities and we welcome flexible working requests from point of hire to support employees work life balance. We are looking for employees who aspire to excellence, share our values and can play a crucial role in our on-going achievements.
Job description
Job responsibilities
For further information on this role, please see the attached detailed Job Description and Person Specification:
- To assist with the setup of RM/ICR translational research studies, from protocol inception and submission to CCR, Regulatory Authorities, to processing amendments.
- To assist in the development of the EHE Biobank along with submission to CCR, Regulatory Authorities and maintaining approvals.
- Contribute to preparation of trial documentation e.g. trial guidance notes and case report forms (CRFs) in collaboration with relevant members of the Trial Management Group including the CI, Clinical Fellow (where relevant), Clinical Trial Database Programmer and Statistician.
- Set up and maintain Trial Master File and support the unit in the setup and maintenance of Investigator Site Files.
Job description
Job responsibilities
For further information on this role, please see the attached detailed Job Description and Person Specification:
- To assist with the setup of RM/ICR translational research studies, from protocol inception and submission to CCR, Regulatory Authorities, to processing amendments.
- To assist in the development of the EHE Biobank along with submission to CCR, Regulatory Authorities and maintaining approvals.
- Contribute to preparation of trial documentation e.g. trial guidance notes and case report forms (CRFs) in collaboration with relevant members of the Trial Management Group including the CI, Clinical Fellow (where relevant), Clinical Trial Database Programmer and Statistician.
- Set up and maintain Trial Master File and support the unit in the setup and maintenance of Investigator Site Files.
Person Specification
Education/Qualifications
Essential
- Educated to degree level or equivalent experience
Desirable
- Higher degree qualification (eg MSc)
Experience
Essential
- Experience of specimen handling, processing and work on translational studies
- Experience of working in a clinical research environment within NHS or University
- Experience of working across organisational boundaries with multi-disciplinary teams
- Experience of communicating effectively with all levels of staff - written and verbal
- Specimen document control skills and HTA knowledge
Desirable
- Possess good organisational and interpersonal skills
- Clear understanding of cancer research and an interest in translational research
Skills Abilities/knowledge
Essential
- Detailed knowledge of UK Clinical trial regulations, GCP and HTA regulatory framework
- Knowledge of the requirements of clinical trials and clinical research projects during their life-cycle
- Knowledge of systems and processes required to conduct clinical trials in accordance with clinical trial regulations
- Tissue processing skills, knowledge of tissue tracking systems and experience with translational study audits.
- Proficient in using PC based Windows and Microsoft Office software including the Internet and E-mail
Other Requirements
Essential
- Ability to work in a proactive manner to identify new risks and issues and flag upwards appropriately.
- Maintain a positive and enthusiastic attitude towards tasks and their goals.
- Ability to work well within a multi-disciplinary team environment in an effective and supportive way.
- Able to work under pressure, methodical in approach, with effective problemsolving ability
- Ability to work effectively to tight deadlines under direction and on own initiative
- A high level of accuracy and attention to detail
- Ability to prioritise workload
- Ability to negotiate, acting in a tactful and confidence manner to achieve the desired results
- Willing and able to coach and train others
Person Specification
Education/Qualifications
Essential
- Educated to degree level or equivalent experience
Desirable
- Higher degree qualification (eg MSc)
Experience
Essential
- Experience of specimen handling, processing and work on translational studies
- Experience of working in a clinical research environment within NHS or University
- Experience of working across organisational boundaries with multi-disciplinary teams
- Experience of communicating effectively with all levels of staff - written and verbal
- Specimen document control skills and HTA knowledge
Desirable
- Possess good organisational and interpersonal skills
- Clear understanding of cancer research and an interest in translational research
Skills Abilities/knowledge
Essential
- Detailed knowledge of UK Clinical trial regulations, GCP and HTA regulatory framework
- Knowledge of the requirements of clinical trials and clinical research projects during their life-cycle
- Knowledge of systems and processes required to conduct clinical trials in accordance with clinical trial regulations
- Tissue processing skills, knowledge of tissue tracking systems and experience with translational study audits.
- Proficient in using PC based Windows and Microsoft Office software including the Internet and E-mail
Other Requirements
Essential
- Ability to work in a proactive manner to identify new risks and issues and flag upwards appropriately.
- Maintain a positive and enthusiastic attitude towards tasks and their goals.
- Ability to work well within a multi-disciplinary team environment in an effective and supportive way.
- Able to work under pressure, methodical in approach, with effective problemsolving ability
- Ability to work effectively to tight deadlines under direction and on own initiative
- A high level of accuracy and attention to detail
- Ability to prioritise workload
- Ability to negotiate, acting in a tactful and confidence manner to achieve the desired results
- Willing and able to coach and train others
Disclosure and Barring Service Check
This post is subject to the Rehabilitation of Offenders Act (Exceptions Order) 1975 and as such it will be necessary for a submission for Disclosure to be made to the Disclosure and Barring Service (formerly known as CRB) to check for any previous criminal convictions.
