Job summary
With the scope of digital pathology, pathologists are now able to convert glass slides of patients' tissue samples into digital slides that can be viewed and analysed on a computer. The Integrated Pathology Unit (IPU) runs one of the most advanced translational digital pathology operations in Europe and bridges the gap between science and patients within the scope of digital pathology, tissue hybridization and artificial intelligence (AI) technologies. The IPU represents an opportunity to make a substantial impact to the way we understand, diagnose and characterize cancer. The IPU works with teams at The Royal Marsden, the ICR, international and national collaborators, research organizations and commercial partners. This role plays a key part in the future of the IPU as we begin to enter a new realm of regulatory compliance with applications of AI and digitisation of pathology material, and multimodal analysis. As these techniques become the new norm, we need to ensure they are seamlessly integrated into new study setups and future translational research. The ultimate aim being primarily, to make it easier and quicker to set-up and deliver more complex tissue- and data-driven research. The post holder will be responsible for coordinating and facilitating all the activities required for the effective access to and monitoring of clinical images, biomaterials and meta-data for individual projects initiated by RMH or ICR scientists.
Main duties of the job
The holder of the post is expected to perform a variety of tasks that may include, but are not restricted to:
- Responsible for coordinating and facilitating all the activities required for the effective access to clinical images, biomaterials and meta-data for individual projects initiated by RMH or ICR scientists
- Monitor the use of clinical images, biomaterials and meta-data in individual projects
- Support and actively engage in the creation of the documentation required for each study, in relation to access to clinical images, biomaterials and meta-data in individual projects
About us
The Royal Marsden NHS Foundation Trust is a world-leading cancer centre. Our role is to offer our patients the best cancer care available anywhere in the world, and to continue to make a global contribution to finding better ways of diagnosing and treating cancer. We employ over 4,500 staff in a diverse range of careers including nursing, medical, science, radiography, pharmacy, occupational therapy, finance and administrative services. We have two hospitals - one in Chelsea, London, and one in Sutton, Surrey - as well as a Medical Daycare Unit in Kingston Hospital.
At The Royal Marsden, we deal with cancer every day, so we understand how valuable life is. When people entrust their lives to us, they have the right to demand the very best. That's why the pursuit of excellence lies at the heart of everything we do.
At the heart of the hospital is our dedicated team. We offer a stimulating and dynamic working environment, a wide range of staff benefits, learning and development opportunities and clear career pathways. There are opportunities to work flexibly across a range of areas and specialities and we welcome flexible working requests from point of hire to support employees work life balance. We are looking for employees who aspire to excellence, share our values and can play a crucial role in our on-going achievements.
Job description
Job responsibilities
Service Delivery:
The Integrated Pathology Unit will oversee and contribute to a wide range of projects, clinical trials and RM/ICR led academic studies. This may include multicentre trials, UK Clinical Trials of Investigational Medicinal Product (CTIMP) to retrospective translational research projects. The postholder will:
- Work with IPU leadership to create a strong, robust and efficient pipeline to coordinate and facilitate all the activities required for the effective access to clinical images, biomaterials and meta-data for individual projects initiated by RMH or ICR scientists
- Coordinate, navigate and facilitate all regulatory internal requirements including (when applicable):
- Medicines for Human Use (Clinical Trials) Regulations
- Research Governance Framework for Health and Social Care
- Human Tissue Act
- Research and Development Policies and SOPs
- Be the main point of contact for the clinical R&D Office for set up of assigned R&D projects.
- Assist in preparation for audits and regulatory Inspections
- Establish and maintain good channels of communication within the clinical research team, with other departments within the Trust and with other relevant organisations including non-commercial bodies and funders.
- Attend all relevant network meetings and study setup meetings
- Contribute to bio-specimen and clinical data collection for all cohorts/projects within the Integrated Pathology Unit
- Contribute to de-anonymisation/de-identification of bio-specimen and clinical data and monitoring of data governance.
- Ensure timely and efficient procedures for collection and verification of translational data.
General Duties:
- Work in a flexible, but organised manner
- Meet objectives within predetermined timescales
- Communicate effectively with other members of the Centre of Molecular Pathology, the BRC and other Trust staff
- Work under the supervision of the line manager and to consult where appropriate
- Ensure that all Trust and IPU policies and standard operating procedures are adhered to
- Collaborate and communicate effectively with teams in the institute and clinical colleagues
- Aid in the implementation of corrective and preventative measures within the Unit as agreed with the Unit Head
- Any other duties, which may be required, consistent with the nature and grade of the post
Education and professional development:
- Be responsible for maintaining own professional development and be aware of current practices and future developments within the Trust and National Health Service.
- The job description is a reflection of the present position. It is expected that there will be a need to regularly review and amend the contents in light of any future changes and developments. Any necessary amendments will be discussed in full with the post holder.
Job description
Job responsibilities
Service Delivery:
The Integrated Pathology Unit will oversee and contribute to a wide range of projects, clinical trials and RM/ICR led academic studies. This may include multicentre trials, UK Clinical Trials of Investigational Medicinal Product (CTIMP) to retrospective translational research projects. The postholder will:
- Work with IPU leadership to create a strong, robust and efficient pipeline to coordinate and facilitate all the activities required for the effective access to clinical images, biomaterials and meta-data for individual projects initiated by RMH or ICR scientists
- Coordinate, navigate and facilitate all regulatory internal requirements including (when applicable):
- Medicines for Human Use (Clinical Trials) Regulations
- Research Governance Framework for Health and Social Care
- Human Tissue Act
- Research and Development Policies and SOPs
- Be the main point of contact for the clinical R&D Office for set up of assigned R&D projects.
- Assist in preparation for audits and regulatory Inspections
- Establish and maintain good channels of communication within the clinical research team, with other departments within the Trust and with other relevant organisations including non-commercial bodies and funders.
- Attend all relevant network meetings and study setup meetings
- Contribute to bio-specimen and clinical data collection for all cohorts/projects within the Integrated Pathology Unit
- Contribute to de-anonymisation/de-identification of bio-specimen and clinical data and monitoring of data governance.
- Ensure timely and efficient procedures for collection and verification of translational data.
General Duties:
- Work in a flexible, but organised manner
- Meet objectives within predetermined timescales
- Communicate effectively with other members of the Centre of Molecular Pathology, the BRC and other Trust staff
- Work under the supervision of the line manager and to consult where appropriate
- Ensure that all Trust and IPU policies and standard operating procedures are adhered to
- Collaborate and communicate effectively with teams in the institute and clinical colleagues
- Aid in the implementation of corrective and preventative measures within the Unit as agreed with the Unit Head
- Any other duties, which may be required, consistent with the nature and grade of the post
Education and professional development:
- Be responsible for maintaining own professional development and be aware of current practices and future developments within the Trust and National Health Service.
- The job description is a reflection of the present position. It is expected that there will be a need to regularly review and amend the contents in light of any future changes and developments. Any necessary amendments will be discussed in full with the post holder.
Person Specification
Attainments
Essential
- Life sciences (or equivalent) degree
- Well-developed IT (Microsoft Work package) and internet skills
- Competence in research orientated PC software (Databases, Excel, SPSS)
- Evidence of Continuing Professional Development.
Desirable
- Postgraduate or higher level education equivalent in relevant area
Experience
Essential
- Experience in translational/clinical project coordination or working in a clinical research environment
- Detailed understanding and experience of clinical studies, including operational aspects and regulatory framework
- Experience in clinical data collection, curation and maintenance
Special Aptitude & Disposition
Essential
- Advanced organisational skills and ability to manage multiple projects at various stages of development & organisation
- Excellent cross-disciplinary/interagency communication skills and ability to facilitate collaborative working relationships
- Confident and articulate with excellent written and oral communication skills
- Ability to make decisionsand prioritise effectively
- Ability to innovate and respond to change
- Ability to work flexible hours as required to meet service needs
- Ability to work across sites if required
Person Specification
Attainments
Essential
- Life sciences (or equivalent) degree
- Well-developed IT (Microsoft Work package) and internet skills
- Competence in research orientated PC software (Databases, Excel, SPSS)
- Evidence of Continuing Professional Development.
Desirable
- Postgraduate or higher level education equivalent in relevant area
Experience
Essential
- Experience in translational/clinical project coordination or working in a clinical research environment
- Detailed understanding and experience of clinical studies, including operational aspects and regulatory framework
- Experience in clinical data collection, curation and maintenance
Special Aptitude & Disposition
Essential
- Advanced organisational skills and ability to manage multiple projects at various stages of development & organisation
- Excellent cross-disciplinary/interagency communication skills and ability to facilitate collaborative working relationships
- Confident and articulate with excellent written and oral communication skills
- Ability to make decisionsand prioritise effectively
- Ability to innovate and respond to change
- Ability to work flexible hours as required to meet service needs
- Ability to work across sites if required
Disclosure and Barring Service Check
This post is subject to the Rehabilitation of Offenders Act (Exceptions Order) 1975 and as such it will be necessary for a submission for Disclosure to be made to the Disclosure and Barring Service (formerly known as CRB) to check for any previous criminal convictions.
