Moorfields Eye Hospital NHS Foundation Trust

Clinical Research Fellow

Information:

This job is now closed

Job summary

The post will suit a person wishing to develop a career in clinical research as they will attain cutting-edge experience of how to run a clinical trial. The successful candidate will be bright, independent and highly motivated, but willing and able to work effectively as part of a team.

The post-holder will be based in the Clinical Research Facility at Moorfields Eye Hospital and UCL Institute of Ophthalmology. He/she will acquire expertise in the use and interpretation of a range of psychophysical assessments including microperimetry and detailed colour vision assessments, and imaging studies including fundus photography, autofluorescence imaging, and high-resolution optical coherence tomography.

Main duties of the job

The post-holder will be expected to:

  • Collect clinical data (including history, examination findings, any investigations) and collate in a custom-designed database.
  • Work collaboratively with other members of the research team and clinical
  • Recruit and co-ordinate patients for a clinical trial
  • Organise, maintain and analyse project data
  • Data analysis to understand the genotype-phenotype correlations
  • Responsibility for clinical data management and liaison with the lead investigator
  • Active participation in other ongoing research projects
  • Achieve goals, agreed in discussions with their line manager
  • Present the results of the project in national and international meetings
  • Prepare the results of the project for publication
  • Perform any other duties within the scope, spirit and purpose of the post, the title of the post and its grading as requested by their line manager
  • Undertake patient and public involvement exercises to promote the disease and the research

About us

At Moorfields, we provide more than just an excellent career and great colleagues to work with. We also offer:

Salary including High-Cost Area Supplement

Opportunity to join the NHS Pension Scheme

Free 24/7 independent counselling service

Learning and development opportunities

Easy and quick transport links

A range of attractive benefits and discounts

Access to Blue Light Card and other NHS Discount Schemes

Free Pilates classes

Full support and training to develop your skills

Flexible working friendly organization

And so much more! To see the full range of benefits we offer please see our Moorfields benefits document.

Details

Date posted

20 January 2025

Pay scheme

Hospital medical and dental staff

Grade

Doctor - other

Salary

£47,436.14 a year Plus £10,100 Research Supplement pro rata

Contract

Fixed term

Duration

12 months

Working pattern

Part-time

Reference number

273-DC-0274

Job locations

Moorfields Eye Hospital Clinical Trials Unit

City Road

London

EC1V 2PD


Job description

Job responsibilities

The post-holder will be part of an innovative research team led by Professor Mariya Moosajee, Professor of Molecular Ophthalmology at UCL and Consultant Ophthalmologist in the Genetic Service at Moorfields Eye Hospital. The principle aim for this post will be to facilitate research in Stargardt disease. The individual will be involved in the detailed phenotyping of patients with ABCA4 retinopathy to identify suitable participants for the clinical trial and establish the natural history. They will also see the recruited trial patients at their screening, baseline and follow-up visits.

He/she will have the opportunity to publish scientific papers, and potentially register for a higher degree such as a PhD at UCL with full academic support. In addition, the post-holder will also have exposure to genetic eye disease clinics (both paediatric and adult) during their placement.

He/she will acquire expertise in the use and interpretation of a range of psychophysical assessments including microperimetry and detailed colour vision assessments, and imaging studies including fundus photography, autofluorescence imaging, and high-resolution optical coherence tomography. Whilst experience in some of these techniques would be an advantage, full training will be provided where necessary, so candidates lacking direct experience in these areas but having the necessary background skills and showing technical aptitude are also encouraged to apply.

The post-holder will be expected to:

  • Collect genetic and clinical data (including history, examination findings, any investigations) and collate in a custom-designed database.
  • Work collaboratively with other members of the research team and clinical
  • Recruit and co-ordinate patients for a clinical trial
  • Organise, maintain and analyse project data
  • Data analysis to understand the genotype-phenotype correlations
  • Responsibility for clinical data management and liaison with the lead investigator
  • Participate in weekly laboratory meetings
  • Active participation in other ongoing research projects
  • Achieve goals, agreed in discussions with their line manager
  • Present the results of the project in national and international meetings
  • Prepare the results of the project for publication
  • Perform any other duties within the scope, spirit and purpose of the post, the title of the post and its grading as requested by their line manager
  • Undertake patient and public involvement exercises to promote the disease and the research

Job description

Job responsibilities

The post-holder will be part of an innovative research team led by Professor Mariya Moosajee, Professor of Molecular Ophthalmology at UCL and Consultant Ophthalmologist in the Genetic Service at Moorfields Eye Hospital. The principle aim for this post will be to facilitate research in Stargardt disease. The individual will be involved in the detailed phenotyping of patients with ABCA4 retinopathy to identify suitable participants for the clinical trial and establish the natural history. They will also see the recruited trial patients at their screening, baseline and follow-up visits.

He/she will have the opportunity to publish scientific papers, and potentially register for a higher degree such as a PhD at UCL with full academic support. In addition, the post-holder will also have exposure to genetic eye disease clinics (both paediatric and adult) during their placement.

He/she will acquire expertise in the use and interpretation of a range of psychophysical assessments including microperimetry and detailed colour vision assessments, and imaging studies including fundus photography, autofluorescence imaging, and high-resolution optical coherence tomography. Whilst experience in some of these techniques would be an advantage, full training will be provided where necessary, so candidates lacking direct experience in these areas but having the necessary background skills and showing technical aptitude are also encouraged to apply.

The post-holder will be expected to:

  • Collect genetic and clinical data (including history, examination findings, any investigations) and collate in a custom-designed database.
  • Work collaboratively with other members of the research team and clinical
  • Recruit and co-ordinate patients for a clinical trial
  • Organise, maintain and analyse project data
  • Data analysis to understand the genotype-phenotype correlations
  • Responsibility for clinical data management and liaison with the lead investigator
  • Participate in weekly laboratory meetings
  • Active participation in other ongoing research projects
  • Achieve goals, agreed in discussions with their line manager
  • Present the results of the project in national and international meetings
  • Prepare the results of the project for publication
  • Perform any other duties within the scope, spirit and purpose of the post, the title of the post and its grading as requested by their line manager
  • Undertake patient and public involvement exercises to promote the disease and the research

Person Specification

EDUCATION & QUALIFICATIONS

Essential

  • MBBS or equivalent medical qualification.
  • FRCOphth
  • Full GMC Registration (with a Licence to Practice) or be eligible for GMC Registration.

Desirable

  • Ophthalmology research experience

FURTHER TRAINING & KNOWLEDGE

Essential

  • Completion of Specialist Ophthalmology Training or Equivalent.

Desirable

  • Completion of Good Clinical Practice (GCP) course in the last two years.

EXPERIENCE

Essential

  • Run a clinical trial

Desirable

  • Undertaken a natural history study in IRDs
Person Specification

EDUCATION & QUALIFICATIONS

Essential

  • MBBS or equivalent medical qualification.
  • FRCOphth
  • Full GMC Registration (with a Licence to Practice) or be eligible for GMC Registration.

Desirable

  • Ophthalmology research experience

FURTHER TRAINING & KNOWLEDGE

Essential

  • Completion of Specialist Ophthalmology Training or Equivalent.

Desirable

  • Completion of Good Clinical Practice (GCP) course in the last two years.

EXPERIENCE

Essential

  • Run a clinical trial

Desirable

  • Undertaken a natural history study in IRDs

Disclosure and Barring Service Check

This post is subject to the Rehabilitation of Offenders Act (Exceptions Order) 1975 and as such it will be necessary for a submission for Disclosure to be made to the Disclosure and Barring Service (formerly known as CRB) to check for any previous criminal convictions.

Certificate of Sponsorship

Applications from job seekers who require current Skilled worker sponsorship to work in the UK are welcome and will be considered alongside all other applications. For further information visit the UK Visas and Immigration website (Opens in a new tab).

From 6 April 2017, skilled worker applicants, applying for entry clearance into the UK, have had to present a criminal record certificate from each country they have resided continuously or cumulatively for 12 months or more in the past 10 years. Adult dependants (over 18 years old) are also subject to this requirement. Guidance can be found here Criminal records checks for overseas applicants (Opens in a new tab).

UK Registration

Applicants must have current UK professional registration. For further information please see NHS Careers website (opens in a new window).

Additional information

Disclosure and Barring Service Check

This post is subject to the Rehabilitation of Offenders Act (Exceptions Order) 1975 and as such it will be necessary for a submission for Disclosure to be made to the Disclosure and Barring Service (formerly known as CRB) to check for any previous criminal convictions.

Certificate of Sponsorship

Applications from job seekers who require current Skilled worker sponsorship to work in the UK are welcome and will be considered alongside all other applications. For further information visit the UK Visas and Immigration website (Opens in a new tab).

From 6 April 2017, skilled worker applicants, applying for entry clearance into the UK, have had to present a criminal record certificate from each country they have resided continuously or cumulatively for 12 months or more in the past 10 years. Adult dependants (over 18 years old) are also subject to this requirement. Guidance can be found here Criminal records checks for overseas applicants (Opens in a new tab).

UK Registration

Applicants must have current UK professional registration. For further information please see NHS Careers website (opens in a new window).

Employer details

Employer name

Moorfields Eye Hospital NHS Foundation Trust

Address

Moorfields Eye Hospital Clinical Trials Unit

City Road

London

EC1V 2PD


Employer's website

https://www.moorfields.nhs.uk/work-for-us (Opens in a new tab)


Employer details

Employer name

Moorfields Eye Hospital NHS Foundation Trust

Address

Moorfields Eye Hospital Clinical Trials Unit

City Road

London

EC1V 2PD


Employer's website

https://www.moorfields.nhs.uk/work-for-us (Opens in a new tab)


Employer contact details

For questions about the job, contact:

Consultant Ophthalmologist

Mariya Moosajee

m.moosajee@nhs.net

Details

Date posted

20 January 2025

Pay scheme

Hospital medical and dental staff

Grade

Doctor - other

Salary

£47,436.14 a year Plus £10,100 Research Supplement pro rata

Contract

Fixed term

Duration

12 months

Working pattern

Part-time

Reference number

273-DC-0274

Job locations

Moorfields Eye Hospital Clinical Trials Unit

City Road

London

EC1V 2PD


Supporting documents

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