Job summary
Come and join our research team and help us develop genetic services Band 8a Senior Translational Scientist required
Do you want to help us transform NHS prenatal diagnostic and geneticservices? We are seeking a skilled and enthusiastic Scientist funded by theGreat Ormond Street Biomedical Research Centre to join our team based in the NHS North Thames Genomic Laboratory Hub at Great Ormond Street Hospital. Our team is delivering transformation in patient care by using circulating cell free DNA to develop new approaches for safe prenatal diagnosis, pipelines for rapid, comprehensive diagnosis of paediatric conditions such as early onset epilepsy using genome sequencing andutilising long read sequencing technologies to transform clinical services. In addition, as one of the biggest recruiters to the 100,000 Genomes Project, we are now exploring new approaches to identify causative variants in unsolved cases.
Main duties of the job
If you are committed to contributing to a team delivering excellence inresearch into genetics and would like to gain experience in translationalresearch this is definitely the post for you. This Band 8a post is availableimmediately, funded until 31st March 2028 in the first instance, with apossibility of extension if we are successful in renewing the BRC. You will be joining an enthusiastic, friendly, motivated multidisciplinary research team working closely with the Clinical Scientific and Bioinformatics team. This is an ideal opportunity to contribute to the translation of research into clinical practice for the benefit of our patients. It's a great chance to experience working in an expert translational research environment based in a thriving Genomic Laboratory Hub closely affiliated to the academic environment of the UCL GOS Institute of Child Health. This post is also suitable for experienced Clinical scientists wanting to broaden their horizons and undertake a secondment to gain experience of translational research. Hybrid working is supported, however, after the probation period a minimum of 40% on site working is required.
About us
We are keen to make our workforce as diverse as the communities we serve, and we hope to attract applications from underrepresented groups, including people with Black, Asian and Minority Ethnic heritage, people with a disability, and people from LGBTQ+ communities. By growing an ever more diverse workforce, we'll have a greater range of perspectives and knowledge, meaning that we can provide the children and young people at our hospital with even better care.
Our hospital is committed to creating an environment that is open and inclusive. Our staff are encouraged to engage with colleagues through the following networks: REACH (Race, Ethnicity and Cultural Heritage) ENABLED (Enhancing Abilities & Leveraging Disabilities Network), PRIDE and Women's networks; all of which are sponsored by a member of our Executive Management Team.
We want to ensure that all of our people, regardless of their background, are seen and heard. We want to attract applicants that share our commitment to inclusion and that understand diversity is a strength that is embraced and valued.
Job description
Job responsibilities
The full job description provides an overview of the key tasks and responsibilities of the role, and the person specification outlines the qualifications, skills, experience and knowledge required. For both documents please view the attachment/s below.
Job description
Job responsibilities
The full job description provides an overview of the key tasks and responsibilities of the role, and the person specification outlines the qualifications, skills, experience and knowledge required. For both documents please view the attachment/s below.
Person Specification
GOSH Culture and Values
Essential
- Our Always Values
- Knowledge and Understanding of diverse backgrounds and perspectives.
- Understanding of Diversity and Inclusion challenges in the workplace.
- Demonstrable contribution to advancing Equality, Diversity and Inclusion in the Workplace
- Ability to work on site when required
Academic/Professional qualification/Training
Essential
- PhD related to genomics or equivalent experience
- 1st or 2nd class honours degree in genetics or a relevant biological subject
- State Registered Clinical Scientist (HCPC)
Desirable
- Commitment to RCPath Fellowship
Experience/Knowledge
Essential
- At least 5 years postgraduate experience in a molecular genetics laboratory
- Extensive & comprehensive knowledge of molecular genetics and the development / translation of methods / techniques
- Experience of research in genetics
- Up to date knowledge of scientific literature and best practice guidance relating to molecular genetic tests
Desirable
- Experience of staff management
- Track record of scientific first author publications
- Evidence of supervising/training other staff
- Knowledge of appropriate Quality Management and Audit regulations and requirements
- Up to date knowledge of cell free DNA
- Up to date knowledge of long read sequencing techniques
- Knowledge of appropriate Health and Safety regulations and requirements
Skills/Abilities
Essential
- Skilled in the use of genetics techniques including NGS technologies
- Evidence of excellent inter-personal communication skills
- Excellent organisational and time management skills with ability to prioritise tasks effectively
- Able to establish and validate new techniques / tests including ability to troubleshoot. Willing to adapt to changes in methodology
- Ability to develop and maintain excellent communication and working relationships
- Proactive and innovative approach to service improvement and delivery
- Computer literate, including use of DNA/Genetic databases, analytical software, variant classification
- Ability to collate, write, publish and present research findings
Desirable
- Familiar with Genetic analysers, robotics
Person Specification
GOSH Culture and Values
Essential
- Our Always Values
- Knowledge and Understanding of diverse backgrounds and perspectives.
- Understanding of Diversity and Inclusion challenges in the workplace.
- Demonstrable contribution to advancing Equality, Diversity and Inclusion in the Workplace
- Ability to work on site when required
Academic/Professional qualification/Training
Essential
- PhD related to genomics or equivalent experience
- 1st or 2nd class honours degree in genetics or a relevant biological subject
- State Registered Clinical Scientist (HCPC)
Desirable
- Commitment to RCPath Fellowship
Experience/Knowledge
Essential
- At least 5 years postgraduate experience in a molecular genetics laboratory
- Extensive & comprehensive knowledge of molecular genetics and the development / translation of methods / techniques
- Experience of research in genetics
- Up to date knowledge of scientific literature and best practice guidance relating to molecular genetic tests
Desirable
- Experience of staff management
- Track record of scientific first author publications
- Evidence of supervising/training other staff
- Knowledge of appropriate Quality Management and Audit regulations and requirements
- Up to date knowledge of cell free DNA
- Up to date knowledge of long read sequencing techniques
- Knowledge of appropriate Health and Safety regulations and requirements
Skills/Abilities
Essential
- Skilled in the use of genetics techniques including NGS technologies
- Evidence of excellent inter-personal communication skills
- Excellent organisational and time management skills with ability to prioritise tasks effectively
- Able to establish and validate new techniques / tests including ability to troubleshoot. Willing to adapt to changes in methodology
- Ability to develop and maintain excellent communication and working relationships
- Proactive and innovative approach to service improvement and delivery
- Computer literate, including use of DNA/Genetic databases, analytical software, variant classification
- Ability to collate, write, publish and present research findings
Desirable
- Familiar with Genetic analysers, robotics
Disclosure and Barring Service Check
This post is subject to the Rehabilitation of Offenders Act (Exceptions Order) 1975 and as such it will be necessary for a submission for Disclosure to be made to the Disclosure and Barring Service (formerly known as CRB) to check for any previous criminal convictions.
Applications from job seekers who require current Skilled worker sponsorship to work in the UK are welcome and will be considered alongside all other applications. For further information visit the UK Visas and Immigration website (Opens in a new tab).
From 6 April 2017, skilled worker applicants, applying for entry clearance into the UK, have had to present a criminal record certificate from each country they have resided continuously or cumulatively for 12 months or more in the past 10 years. Adult dependants (over 18 years old) are also subject to this requirement. Guidance can be found here Criminal records checks for overseas applicants (Opens in a new tab).
UK Registration
Applicants must have current UK professional registration. For further information please see
NHS Careers website (opens in a new window).
Additional information
Disclosure and Barring Service Check
This post is subject to the Rehabilitation of Offenders Act (Exceptions Order) 1975 and as such it will be necessary for a submission for Disclosure to be made to the Disclosure and Barring Service (formerly known as CRB) to check for any previous criminal convictions.
Applications from job seekers who require current Skilled worker sponsorship to work in the UK are welcome and will be considered alongside all other applications. For further information visit the UK Visas and Immigration website (Opens in a new tab).
From 6 April 2017, skilled worker applicants, applying for entry clearance into the UK, have had to present a criminal record certificate from each country they have resided continuously or cumulatively for 12 months or more in the past 10 years. Adult dependants (over 18 years old) are also subject to this requirement. Guidance can be found here Criminal records checks for overseas applicants (Opens in a new tab).
UK Registration
Applicants must have current UK professional registration. For further information please see
NHS Careers website (opens in a new window).
Employer details
Employer name
Great Ormond Street Hospital for Children NHS Foundation Trust
Address
Barclay House, Great Ormond Street Hospital
37 Queen Square
London
WC1N 3JH
Employer's website
https://www.gosh.nhs.uk/ (Opens in a new tab)
