Job summary
Do you want to help us transform NHS diagnostic genetic services? We are seeking a skilled and enthusiastic scientist funded by the NIHR Great Ormond Street Biomedical Research Centre to join our team based in the North Thames Genomic Laboratory. Our team is delivering transformation in patient care by using circulating cell free DNA to develop new approaches for safer prenatal diagnosis, pipelines for rapid, comprehensive diagnosis of paediatric conditions such as early onset epilepsy using whole genome sequencing and utilising long read sequencing technologies to transform clinical services. In addition, as one of the biggest recruiters to the 100,000 Genomes study, we are now exploring new approaches to identify causative variants in unsolved cases.
Main duties of the job
If you are committed to contributing to a team delivering excellence in research in genomics and would like to gain experience in translational research this is definitely the post for you. This Band 7 post is available immediately, funded until 30th November 2027. You will be joining an enthusiastic, friendly, motivated multidisciplinary team working closely with the Clinical Scientific and Bioinformatics team. This is an ideal opportunity to contribute to the translation of research into clinical practice for the benefit of our patients. This post is suitable for research or postdoctoral scientists wanting to explore the exciting area of translational research, or registered clinical scientists who want to broaden their horizons with more research experience. It's a great chance to experience working in an expert translational research environment based in a thriving Genomic Laboratory Hub closely affiliated to the academic environment of the UCL GOS Institute of Child Health. Hybrid working is supported, however, after the probation period a minimum of 40% on site working is required.
For enquiries or an informal visit please contact Natalie Chandler - natalie.chandler@gosh.nhs.uk or Elizabeth Scotchman - elizabeth.scotchman@gosh.nhs.uk.
About us
GOSH is committed to recruiting the best person for the job, based solely on their ability and individual merit as measured against the criteria for the role; through a process that is fair, open, consistent and free from bias and discrimination.
We are committed to being a diverse and inclusive employer and foster a culture where all staff are valued, respected and acknowledged. All applicants will receive consideration for employment without regard to race, colour, national origin, religion, sexual orientation, gender, gender identity, age, disability status or length of time spent unemployed.We particularly welcome applications from BAME communities, people with disabilities and/or long-term health conditions and LGBT+ community members.
We have policies and procedures in place to ensure that all applicants and employees are treated fairly and consistently. We are proud to be accredited as a Disability Confident Employer, a member of Business Disability Forum and a Stonewall Diversity Champion.
We have active and Executive supported BAME, LGBT+ and Allies, Disability and Long-Term Health Conditions and Women's staff networks.
Staff networks are employee-led groups formed around interests, issues and a common bond or background. Staff network members create a positive and inclusive work environment at Great Ormond Street Hospital by actively contributing to the Trust's mission, values and efforts specific to inclusion. All of our staff networks are open to any employee
Job description
Job responsibilities
The full job description provides an overview of the key tasks and responsibilities of the role, and the person specification outlines the qualifications, skills, experience and knowledge required. For both documents please view the attachment/s below
Job description
Job responsibilities
The full job description provides an overview of the key tasks and responsibilities of the role, and the person specification outlines the qualifications, skills, experience and knowledge required. For both documents please view the attachment/s below
Person Specification
GOSH Culture and Values
Essential
- Our Always values
- Knowledge and Understanding of diverse backgrounds and perspectives
- Understanding of Diversity and Inclusion challenges in the workplace
- Demonstrable contribution to advancing Equality, Diversity and Inclusion in the Workplace
Academic/Professional qualification/Training
Essential
- 1st or 2nd class honours degree in genetics or a relevant biological subject
- PhD related to genomics or equivalent experience
Desirable
- State Registered Clinical Scientist (HCPC)
Experience/Knowledge
Essential
- Postgraduate experience in a molecular genetics laboratory
- Extensive & comprehensive knowledge of molecular genetics and the development / translation of methods / techniques
- Experience of research in molecular genetics
- Up to date knowledge of scientific literature and best practice guidance relating to molecular genetic tests
Desirable
- Track record of scientific first author publications
- Evidence of supervising/training other staff
- Knowledge of appropriate Quality Management and Audit regulations and requirements
- Up to date knowledge of cell free DNA
- Up to date knowledge of long read sequencing techniques
- Knowledge of appropriate Health and Safety regulations and requirements
Skills/Abilities
Essential
- Skilled in the use of molecular genetics techniques including NGS technologies
- Evidence of excellent inter-personal communication skills
- Excellent organisational and time management skills with ability to prioritise tasks effectively
- Able to establish and validate new techniques / tests including ability to troubleshoot. Willing to adapt to changes in methodology
- Ability to develop and maintain excellent communication and working relationships
- Proactive and innovative approach to service improvement and delivery
- Computer literate, including use of DNA/Genetic databases, analytical software, variant classification
- Ability to collate, write, publish and present research findings
Desirable
- Familiar with Molecular Genetic analysers, robotics
Person Specification
GOSH Culture and Values
Essential
- Our Always values
- Knowledge and Understanding of diverse backgrounds and perspectives
- Understanding of Diversity and Inclusion challenges in the workplace
- Demonstrable contribution to advancing Equality, Diversity and Inclusion in the Workplace
Academic/Professional qualification/Training
Essential
- 1st or 2nd class honours degree in genetics or a relevant biological subject
- PhD related to genomics or equivalent experience
Desirable
- State Registered Clinical Scientist (HCPC)
Experience/Knowledge
Essential
- Postgraduate experience in a molecular genetics laboratory
- Extensive & comprehensive knowledge of molecular genetics and the development / translation of methods / techniques
- Experience of research in molecular genetics
- Up to date knowledge of scientific literature and best practice guidance relating to molecular genetic tests
Desirable
- Track record of scientific first author publications
- Evidence of supervising/training other staff
- Knowledge of appropriate Quality Management and Audit regulations and requirements
- Up to date knowledge of cell free DNA
- Up to date knowledge of long read sequencing techniques
- Knowledge of appropriate Health and Safety regulations and requirements
Skills/Abilities
Essential
- Skilled in the use of molecular genetics techniques including NGS technologies
- Evidence of excellent inter-personal communication skills
- Excellent organisational and time management skills with ability to prioritise tasks effectively
- Able to establish and validate new techniques / tests including ability to troubleshoot. Willing to adapt to changes in methodology
- Ability to develop and maintain excellent communication and working relationships
- Proactive and innovative approach to service improvement and delivery
- Computer literate, including use of DNA/Genetic databases, analytical software, variant classification
- Ability to collate, write, publish and present research findings
Desirable
- Familiar with Molecular Genetic analysers, robotics
Disclosure and Barring Service Check
This post is subject to the Rehabilitation of Offenders Act (Exceptions Order) 1975 and as such it will be necessary for a submission for Disclosure to be made to the Disclosure and Barring Service (formerly known as CRB) to check for any previous criminal convictions.
Applications from job seekers who require current Skilled worker sponsorship to work in the UK are welcome and will be considered alongside all other applications. For further information visit the UK Visas and Immigration website (Opens in a new tab).
From 6 April 2017, skilled worker applicants, applying for entry clearance into the UK, have had to present a criminal record certificate from each country they have resided continuously or cumulatively for 12 months or more in the past 10 years. Adult dependants (over 18 years old) are also subject to this requirement. Guidance can be found here Criminal records checks for overseas applicants (Opens in a new tab).
UK Registration
Applicants must have current UK professional registration. For further information please see
NHS Careers website (opens in a new window).
Additional information
Disclosure and Barring Service Check
This post is subject to the Rehabilitation of Offenders Act (Exceptions Order) 1975 and as such it will be necessary for a submission for Disclosure to be made to the Disclosure and Barring Service (formerly known as CRB) to check for any previous criminal convictions.
Applications from job seekers who require current Skilled worker sponsorship to work in the UK are welcome and will be considered alongside all other applications. For further information visit the UK Visas and Immigration website (Opens in a new tab).
From 6 April 2017, skilled worker applicants, applying for entry clearance into the UK, have had to present a criminal record certificate from each country they have resided continuously or cumulatively for 12 months or more in the past 10 years. Adult dependants (over 18 years old) are also subject to this requirement. Guidance can be found here Criminal records checks for overseas applicants (Opens in a new tab).
UK Registration
Applicants must have current UK professional registration. For further information please see
NHS Careers website (opens in a new window).
Employer details
Employer name
Great Ormond Street Hospital for Children NHS Foundation Trust
Address
Great Ormond Street Hospital for Children NHS Foundation Trust
Great Ormond Street Hospital
London
WC1N 3JH
Employer's website
https://www.gosh.nhs.uk/ (Opens in a new tab)
