Job summary
The Dubowitz Neuromuscular Centre follows a large number of children affected by a variety of neuromuscular disorders. The Centre is engaged in research focused on the genetic basis of the neuromuscular conditions and in translational research especially in congenital dystrophies, Duchenne muscular dystrophy (MDM) and spinal muscular atrophy (SMA).
This post offers an exciting opportunity for candidates seeking to carry out research and gain experience in clinical trials and translational research in neuromuscular diseases within an established national center of excellence.
The post holder will work on research projects and will contribute to some clinical activities of the Unit, in particular related to the SMA clinics, and to support and coordinate the drug administration and data collection into the SMA REACH UK database for the Nusinersen managed access agreement (MAA).
The research projects will consist mainly in managing clinical trial assessments on patients affected by different neuromuscular conditions (DMD and SMA among them).
Main duties of the job
The post holder will work on research projects and will contribute to some clinical activities of the Unit.
The research projects will consist mainly in managing clinical trial assessments on patients affected by different neuromuscular diseases. In particular the post holder will be involved in recruiting and evaluating patients in different studies on Duchenne Muscular Dystrophy, Spinal Muscular Atrophy, Congenital Muscular Dystrophies and congenital myopathies.
The post holder will be encouraged and supported in conducting clinical audits at GOSH and small research projects on different aspects of neuromuscular conditions and in getting their research published in an international peer-reviewed Journal.
Clinical commitment will include clerking and managing children with neuromuscular disorders in outpatients and day-case settings at GOSH. The appointee will acquire skills in the assessment, diagnostic pathway and multidisciplinary management of neuromuscular disorders. All patients assessed by the clinical research fellow will be reviewed jointly with a consultant and support and supervision will be available from senior colleagues at all times. This will provide a unique opportunity to gain experience in the rapidly changing field of paediatric neuromuscular disorders, within an MDUK recognised paediatric centre for clinical excellence and research.
About us
GOSH is committed to recruiting the best person for the job, based solely on their ability and individual merit as measured against the criteria for the role; through a process that is fair, open, consistent and free from bias and discrimination.
We are committed to being a diverse and inclusive employer and foster a culture where all staff are valued, respected and acknowledged. All applicants will receive consideration for employment without regard to race, colour, national origin, religion, sexual orientation, gender, gender identity, age, disability status or length of time spent unemployed.
We particularly welcome applications from BAME communities, people with disabilities and/or long-term health conditions and LGBT+ community members.
We have policies and procedures in place to ensure that all applicants and employees are treated fairly and consistently. We are proud to be accredited as a Disability Confident Employer, a member of Business Disability Forum and a Stonewall Diversity Champion.
We have active and Executive supported BAME, LGBT+ and Allies, Disability and Long-Term Health Conditions and Women's staff networks. Staff networks are employee-led groups formed around interests, issues and a common bond or background. Staff network members create a positive and inclusive work environment at Great Ormond Street Hospital by actively contributing to the Trust's mission, values and efforts specific to inclusion. All of our staff networks are open to any employee.
Job description
Job responsibilities
Post holder will be involved in recruiting and evaluating patients in different studies on Duchenne Muscular Dystrophy, Spinal Muscular Atrophy, Congenital Muscular Dystrophies and congenital myopathies, including Titin- and Nemaline myopathies.
The post holder will be encouraged and supported in conducting clinical audits at GOSH and small research projects on different aspects of neuromuscular conditions and in getting their research published in an international peer-reviewed Journal.
Clinical commitment will include clerking and managing children with neuromuscular
disorders in outpatients and day-case settings at GOSH
The appointee will acquire skills in the assessment, diagnostic pathway and multidisciplinary management of neuromuscular disorders
All patients assessed by the clinical research fellow will be reviewed jointly with a consultant and support and supervision will be available from senior colleagues at all times.
Job description
Job responsibilities
Post holder will be involved in recruiting and evaluating patients in different studies on Duchenne Muscular Dystrophy, Spinal Muscular Atrophy, Congenital Muscular Dystrophies and congenital myopathies, including Titin- and Nemaline myopathies.
The post holder will be encouraged and supported in conducting clinical audits at GOSH and small research projects on different aspects of neuromuscular conditions and in getting their research published in an international peer-reviewed Journal.
Clinical commitment will include clerking and managing children with neuromuscular
disorders in outpatients and day-case settings at GOSH
The appointee will acquire skills in the assessment, diagnostic pathway and multidisciplinary management of neuromuscular disorders
All patients assessed by the clinical research fellow will be reviewed jointly with a consultant and support and supervision will be available from senior colleagues at all times.
Person Specification
GOSH Culture and Values
Essential
- Always welcoming
- Always helpful
- Always expert
- Always one team
- Knowledge and understanding of diverse backgrounds and perspectives
- Understanding of Diversity and Inclusion challenges in the workplace
- Demonstrable contribution to advancing Equality, Diversity and Inclusion in the Workplace
Academic/Professional qualification/Training
Essential
- Degree in medicine MBBS or Equivalent
- Appropriate GMC registration to be obtained by the designated start date.
Desirable
- Registered with GMC Specialist Registry in Paediatrics, or Adult Neurology or Clinical Genetics
Experience/Knowledge
Essential
- Demonstrated clinical experience in General Paediatrics/ Paediatric Neurology or Adult Neurology or Clinical Genetics
- Prior knowledge in General Paediatric or Paediatric Neurology or Clinical Genetics or Adult Neurology
- Awareness of own limitations, consulting senior colleagues appropriately
Desirable
- Previous exposure to clinical research
- Experience in clinical trials
- Good Clinical Practice training
- Prior knowledge of Neuromuscular Disorders in childhood
Skills/Abilities
Essential
- Excellent oral and written communication skills - Ability to communicate well with colleagues, children and families of patients
- Able to work effectively in a multidisciplinary team
- Computer Literacy/ IT Skills including the use of Microsoft packages (Word, Excel, PowerPoint as minimum)
- Effective spoken and written English
- Excellent communication skills
- Previous research experience
- Knowledge of research design and methods
- Ability to write clearly and concisely
- Scientific & analytical skills
- Knowledge of ethical issues for staff in clinical research
- Excellent organisational and problem solving skills.
Desirable
- Previous research experience
- Knowledge of research design and methods
Personal Qualities
Essential
- Discretion and sensitivity with respect to colleagues and parents of research subjects
- Willingness to learn and adapt to new techniques
- Ability initiate papers and abstracts for conferences and to present material arising from the research
- Excellent interpersonal skills
- Flexible and able to handle conflicting priorities.
Person Specification
GOSH Culture and Values
Essential
- Always welcoming
- Always helpful
- Always expert
- Always one team
- Knowledge and understanding of diverse backgrounds and perspectives
- Understanding of Diversity and Inclusion challenges in the workplace
- Demonstrable contribution to advancing Equality, Diversity and Inclusion in the Workplace
Academic/Professional qualification/Training
Essential
- Degree in medicine MBBS or Equivalent
- Appropriate GMC registration to be obtained by the designated start date.
Desirable
- Registered with GMC Specialist Registry in Paediatrics, or Adult Neurology or Clinical Genetics
Experience/Knowledge
Essential
- Demonstrated clinical experience in General Paediatrics/ Paediatric Neurology or Adult Neurology or Clinical Genetics
- Prior knowledge in General Paediatric or Paediatric Neurology or Clinical Genetics or Adult Neurology
- Awareness of own limitations, consulting senior colleagues appropriately
Desirable
- Previous exposure to clinical research
- Experience in clinical trials
- Good Clinical Practice training
- Prior knowledge of Neuromuscular Disorders in childhood
Skills/Abilities
Essential
- Excellent oral and written communication skills - Ability to communicate well with colleagues, children and families of patients
- Able to work effectively in a multidisciplinary team
- Computer Literacy/ IT Skills including the use of Microsoft packages (Word, Excel, PowerPoint as minimum)
- Effective spoken and written English
- Excellent communication skills
- Previous research experience
- Knowledge of research design and methods
- Ability to write clearly and concisely
- Scientific & analytical skills
- Knowledge of ethical issues for staff in clinical research
- Excellent organisational and problem solving skills.
Desirable
- Previous research experience
- Knowledge of research design and methods
Personal Qualities
Essential
- Discretion and sensitivity with respect to colleagues and parents of research subjects
- Willingness to learn and adapt to new techniques
- Ability initiate papers and abstracts for conferences and to present material arising from the research
- Excellent interpersonal skills
- Flexible and able to handle conflicting priorities.
Disclosure and Barring Service Check
This post is subject to the Rehabilitation of Offenders Act (Exceptions Order) 1975 and as such it will be necessary for a submission for Disclosure to be made to the Disclosure and Barring Service (formerly known as CRB) to check for any previous criminal convictions.
Applications from job seekers who require current Skilled worker sponsorship to work in the UK are welcome and will be considered alongside all other applications. For further information visit the UK Visas and Immigration website (Opens in a new tab).
From 6 April 2017, skilled worker applicants, applying for entry clearance into the UK, have had to present a criminal record certificate from each country they have resided continuously or cumulatively for 12 months or more in the past 10 years. Adult dependants (over 18 years old) are also subject to this requirement. Guidance can be found here Criminal records checks for overseas applicants (Opens in a new tab).
UK Registration
Applicants must have current UK professional registration. For further information please see
NHS Careers website (opens in a new window).
Additional information
Disclosure and Barring Service Check
This post is subject to the Rehabilitation of Offenders Act (Exceptions Order) 1975 and as such it will be necessary for a submission for Disclosure to be made to the Disclosure and Barring Service (formerly known as CRB) to check for any previous criminal convictions.
Applications from job seekers who require current Skilled worker sponsorship to work in the UK are welcome and will be considered alongside all other applications. For further information visit the UK Visas and Immigration website (Opens in a new tab).
From 6 April 2017, skilled worker applicants, applying for entry clearance into the UK, have had to present a criminal record certificate from each country they have resided continuously or cumulatively for 12 months or more in the past 10 years. Adult dependants (over 18 years old) are also subject to this requirement. Guidance can be found here Criminal records checks for overseas applicants (Opens in a new tab).
UK Registration
Applicants must have current UK professional registration. For further information please see
NHS Careers website (opens in a new window).
