Job summary
THREE POSTs Available (ST4 EQUIVALENT OR ABOVE)
12 months fixed term (possibility to extend)
These posts will play a key role in the Experimental Cancer Therapeutics program, which aims to improve the efficiency of introducing novel targeted agents into treatment of children with cancer. The drug development & translational research fellows will be part of a team of doctors, research nurses and data managers and will be based at Great Ormond Street Hospital for Children. These 12-month Clinical Research Fellow posts are particularly suited for a paediatric trained doctor (ST4 or equivalent) who has Paediatric Oncology experience (at least 1 year) and completed MRCPCH (or equivalent international paediatric training). The primary remit of the post holder will be responsibility for phase I/II trials for the testing of new drugs, particularly the new generation of biologically targeted drugs including biotherapeutics as part of our brain and solid tumour CAR-T cell programme. The fellows will support translational research projects such as advanced sample and biomarker development from the clinical coordination aspect.
There posts are due to commence in as soon as possible.
Main duties of the job
The Clinical Research Fellow will work within the multidisciplinary Experimental Cancer Therapeutics team carrying out early clinical studies of agents in children, primarily at Great Ormond Street Hospital. The team is led by Prof Darren Hargrave, Consultant Paediatric Oncologist in Experimental Therapeutics and comprises; Consultant Paediatric Oncologists/ Haematologists, Research Nurses, Clinical Trial Co-ordinators and Data Managers. The Clinical Research Fellows will help recruit to and register patients on Clinical Trials and working with the Experimental Cancer Therapeutics team, the post-holder will be involved in the discussions with the parents about the various options in Early Clinical Trials, and help provide information for the families as appropriate. The post holder will also work with the data managers and be responsible the submission of CRF's for patients on clinical trials. The post holder will work with external monitors on ensuring accurate and documented source data for study patients. Depending on experience, the Fellow(s) will have the opportunity to assist in the development and design of phase I/II clinical trials, submitting applications to Research and Ethics departments and introduction of Phase I/II trials into the clinic. The post holder(s) will also be encouraged to assist in writing grant applications for funding of new drug trials as they become available.
About us
GOSH is committed to recruiting the best person for the job, based solely on their ability and individual merit as measured against the criteria for the role; through a process that is fair, open, consistent and free from bias and discrimination.
We are committed to being a diverse and inclusive employer and foster a culture where all staff are valued, respected and acknowledged. All applicants will receive consideration for employment without regard to race, colour, national origin, religion, sexual orientation, gender, gender identity, age, disability status or length of time spent unemployed.
We particularly welcome applications from BAME communities, people with disabilities and/or long-term health conditions and LGBT+ community members.
We have policies and procedures in place to ensure that all applicants and employees are treated fairly and consistently. We are proud to be accredited as a Disability Confident Employer, a member of Business Disability Forum and a Stonewall Diversity Champion.
We have active and Executive supported BAME, LGBT+ and Allies, Disability and Long-Term Health Conditions and Women's staff networks. Staff networks are employee-led groups formed around interests, issues and a common bond or background. Staff network members create a positive and inclusive work environment at Great Ormond Street Hospital by actively contributing to the Trust's mission, values and efforts specific to inclusion. All of our staff networks are open to any employee.
Job description
Job responsibilities
The full job description provides an overview of the key tasks and responsibilities of the role attached.
The Person Specification outlines the qualifications, skills, experience and knowledge required, both attached.
Job description
Job responsibilities
The full job description provides an overview of the key tasks and responsibilities of the role attached.
The Person Specification outlines the qualifications, skills, experience and knowledge required, both attached.
Person Specification
GOSH Culture and Values
Essential
- Always welcoming
- Always helpful
- Always expert
- Always one team
- Knowledge and understanding of diverse backgrounds and perspectives
Skills/Abilities
Essential
- Confident in the management of sick children and paediatric emergencies
- Ability to communicate well with children and their families and with professional colleagues (written and verbal communications)
- Ability to establish and maintain working relations with patients, carers and multi-disciplinary colleagues
- Ability to work as part of a team
- Medical management - able to supervise junior medical staff
- Ability to work under pressure
- Ability to prioritise clinical needs
- Ability to manage their time and workload
Desirable
- Familiarity and use of IT skills
- Demonstrate involvement in a Clinical Audit Project
- Ability to teach nursing and medical staff
Academic/Professional qualification/Training
Essential
- Appropriate GMC registration by the designated start date
- MRCP, MRCPCH or equivalent
- PALS/APLS
Desirable
- Higher degree - PhD, MD or equivalent
Experience/Knowledge
Essential
- Minimum of 3 years post-registration paediatric experience
- At least 1 years' experience in subspecialty paediatric haematology/oncology
- Experience in teaching
- Experience of leading in Clinical Audit processes
- Strong grounding in general paediatrics
- Awareness of own limitations, consulting senior colleagues appropriately
- Understanding of the principals of clinical governance
- Understanding of principals of patient confidentiality and data protection
Desirable
- 6 months experience in PICU
- Demonstrable research experience including early phase trials
- Management/leadership experience
Other requirements
Essential
- Accountability - takes responsibility for own actions and promotes good team working
- Openness- shares information and good practice appropriately
- Mutual respect - treat others with courtesy and respect at all times
- Commitment to own continued professional development and that of others
- Commitment to the provision of a quality service
Desirable
- Flexible in hours of work in regard to the needs to the team
Person Specification
GOSH Culture and Values
Essential
- Always welcoming
- Always helpful
- Always expert
- Always one team
- Knowledge and understanding of diverse backgrounds and perspectives
Skills/Abilities
Essential
- Confident in the management of sick children and paediatric emergencies
- Ability to communicate well with children and their families and with professional colleagues (written and verbal communications)
- Ability to establish and maintain working relations with patients, carers and multi-disciplinary colleagues
- Ability to work as part of a team
- Medical management - able to supervise junior medical staff
- Ability to work under pressure
- Ability to prioritise clinical needs
- Ability to manage their time and workload
Desirable
- Familiarity and use of IT skills
- Demonstrate involvement in a Clinical Audit Project
- Ability to teach nursing and medical staff
Academic/Professional qualification/Training
Essential
- Appropriate GMC registration by the designated start date
- MRCP, MRCPCH or equivalent
- PALS/APLS
Desirable
- Higher degree - PhD, MD or equivalent
Experience/Knowledge
Essential
- Minimum of 3 years post-registration paediatric experience
- At least 1 years' experience in subspecialty paediatric haematology/oncology
- Experience in teaching
- Experience of leading in Clinical Audit processes
- Strong grounding in general paediatrics
- Awareness of own limitations, consulting senior colleagues appropriately
- Understanding of the principals of clinical governance
- Understanding of principals of patient confidentiality and data protection
Desirable
- 6 months experience in PICU
- Demonstrable research experience including early phase trials
- Management/leadership experience
Other requirements
Essential
- Accountability - takes responsibility for own actions and promotes good team working
- Openness- shares information and good practice appropriately
- Mutual respect - treat others with courtesy and respect at all times
- Commitment to own continued professional development and that of others
- Commitment to the provision of a quality service
Desirable
- Flexible in hours of work in regard to the needs to the team
Disclosure and Barring Service Check
This post is subject to the Rehabilitation of Offenders Act (Exceptions Order) 1975 and as such it will be necessary for a submission for Disclosure to be made to the Disclosure and Barring Service (formerly known as CRB) to check for any previous criminal convictions.
Applications from job seekers who require current Skilled worker sponsorship to work in the UK are welcome and will be considered alongside all other applications. For further information visit the UK Visas and Immigration website (Opens in a new tab).
From 6 April 2017, skilled worker applicants, applying for entry clearance into the UK, have had to present a criminal record certificate from each country they have resided continuously or cumulatively for 12 months or more in the past 10 years. Adult dependants (over 18 years old) are also subject to this requirement. Guidance can be found here Criminal records checks for overseas applicants (Opens in a new tab).
UK Registration
Applicants must have current UK professional registration. For further information please see
NHS Careers website (opens in a new window).
Additional information
Disclosure and Barring Service Check
This post is subject to the Rehabilitation of Offenders Act (Exceptions Order) 1975 and as such it will be necessary for a submission for Disclosure to be made to the Disclosure and Barring Service (formerly known as CRB) to check for any previous criminal convictions.
Applications from job seekers who require current Skilled worker sponsorship to work in the UK are welcome and will be considered alongside all other applications. For further information visit the UK Visas and Immigration website (Opens in a new tab).
From 6 April 2017, skilled worker applicants, applying for entry clearance into the UK, have had to present a criminal record certificate from each country they have resided continuously or cumulatively for 12 months or more in the past 10 years. Adult dependants (over 18 years old) are also subject to this requirement. Guidance can be found here Criminal records checks for overseas applicants (Opens in a new tab).
UK Registration
Applicants must have current UK professional registration. For further information please see
NHS Careers website (opens in a new window).
