Job summary
An exciting research opportunity has arisen investigating the use of a novel point-of care test for pre-eclampsia. The post-holder will be funded by a research grant by the UK National Institute for Health Research and supervised by an internationally renowned team of academic clinicians in the field of Fetal Medicine. The grant is awarded to AG Health and St. George's Healthcare NHS Trust. AG Health want to bring a new test for pre-eclampsia, called Lumella (Glycosylated fibronectin), into the NHS.
Unlike current tests it only needs a pinprick of blood. The International studies indicate that glycosylated fibronectin could also be a more accurate marker for pre-eclampsia than other tests which are currently available.
Sample is analysed on a small machine that is provided free with the tests, and results are available within 10 minutes. The test measures a different type of molecule found in blood to the other tests, called glycosylated fibronectin. This is detected by using labelled antibodies which only bind to the glycosylated fibronectin. These antibodies are then detected by the machine within minutes. The tests can be analysed where the sample is taken (in a clinic or on a hospital ward for example) - that is, at the point-of-care.
Main duties of the job
The post holder will be responsible for the ethical, study-wide and local governance processes relating to this study, as well as patient recruitment, data processing, data analysis, and project write up. Patient recruitment involves identification of women at risk of developing pre-eclampsia, performance of the point-of-care test, collection of baseline and outcome data as well as the performance of growth scans and Dopplers, therefore, Obstetric ultrasound skills are desirable. The candidate should hold a strong interest in Fetal medicine, have a good background knowledge of the conduct of clinical research, as well as an understanding of pre-eclampsia. The project is expected to run at St. George's as well as Epsom/St. Helier sites. The candidate will be expected to work at both the sites. Research passport will be sought to gain access to both the recruiting sites. Support from research midwives will be available.
About us
St George's University of London, together with St George's Hospital, is housed in integrated modern buildings in a large joint campus in Tooting, south London. It is a research-based independently governed and funded specialised health-focused School with academic departments in Bio, Behavioural, Clinical and Social Science. The School is closely integrated with the Hospital's extensive secondary and tertiary clinical NHS provision.
Job description
Job responsibilities
- To be the main point of contact for patients and participants in this research study.
- To identify and recruit patients, ensuring that each patient fulfils the study criteria and effective informed consent is obtained.
- To ensure that the study is conducted strictly in accordance with the study protocol.
- To identify barriers to recruitment and ensure the Chief Investigator/supervisors are made aware of these. Identify and implement action plans as required.
- To ensure that all data is recorded accurately and complies with the requirements of the study protocol and the Data Protection Act.
- To work in conjunction with senior colleagues in preparing submissions to the Joint Research Office and Ethics Committees.
- To lead the production of high-quality peer-reviewed publications and national/ international presentations as required by the funding body or for dissemination to the wider academic community.
- To lead relevant meetings associated with the research project or related activities.
- To liaise with the funding company to ensure that the correct signals are processed, and that all required information are accurately and completely collected.
- To perform statistical analysis of the data collected and provide detailed interpretations.
Job description
Job responsibilities
- To be the main point of contact for patients and participants in this research study.
- To identify and recruit patients, ensuring that each patient fulfils the study criteria and effective informed consent is obtained.
- To ensure that the study is conducted strictly in accordance with the study protocol.
- To identify barriers to recruitment and ensure the Chief Investigator/supervisors are made aware of these. Identify and implement action plans as required.
- To ensure that all data is recorded accurately and complies with the requirements of the study protocol and the Data Protection Act.
- To work in conjunction with senior colleagues in preparing submissions to the Joint Research Office and Ethics Committees.
- To lead the production of high-quality peer-reviewed publications and national/ international presentations as required by the funding body or for dissemination to the wider academic community.
- To lead relevant meetings associated with the research project or related activities.
- To liaise with the funding company to ensure that the correct signals are processed, and that all required information are accurately and completely collected.
- To perform statistical analysis of the data collected and provide detailed interpretations.
Person Specification
Qualifications
Essential
Desirable
Experience
Essential
Desirable
- Experience in trial set up and co-ordination, use of research databases
- Experience of medical teaching and mentoring medical and allied healthcare students and junior professionals
Knowledge/Skills
Essential
- Interest in maternal fetal medicine
- Excellent communication and interpersonal skills
Desirable
- Good Clinical Practice certification
- Ability to develop and deliver high-quality research and to publish in peer-reviewed journals
Personal attributes
Essential
- Flexible and enthusiastic with a good sense of humour
- Good use of initiative and strong organisational and record keeping skills
Person Specification
Qualifications
Essential
Desirable
Experience
Essential
Desirable
- Experience in trial set up and co-ordination, use of research databases
- Experience of medical teaching and mentoring medical and allied healthcare students and junior professionals
Knowledge/Skills
Essential
- Interest in maternal fetal medicine
- Excellent communication and interpersonal skills
Desirable
- Good Clinical Practice certification
- Ability to develop and deliver high-quality research and to publish in peer-reviewed journals
Personal attributes
Essential
- Flexible and enthusiastic with a good sense of humour
- Good use of initiative and strong organisational and record keeping skills
Disclosure and Barring Service Check
This post is subject to the Rehabilitation of Offenders Act (Exceptions Order) 1975 and as such it will be necessary for a submission for Disclosure to be made to the Disclosure and Barring Service (formerly known as CRB) to check for any previous criminal convictions.
Applications from job seekers who require current Skilled worker sponsorship to work in the UK are welcome and will be considered alongside all other applications. For further information visit the UK Visas and Immigration website (Opens in a new tab).
From 6 April 2017, skilled worker applicants, applying for entry clearance into the UK, have had to present a criminal record certificate from each country they have resided continuously or cumulatively for 12 months or more in the past 10 years. Adult dependants (over 18 years old) are also subject to this requirement. Guidance can be found here Criminal records checks for overseas applicants (Opens in a new tab).
UK Registration
Applicants must have current UK professional registration. For further information please see
NHS Careers website (opens in a new window).
Additional information
Disclosure and Barring Service Check
This post is subject to the Rehabilitation of Offenders Act (Exceptions Order) 1975 and as such it will be necessary for a submission for Disclosure to be made to the Disclosure and Barring Service (formerly known as CRB) to check for any previous criminal convictions.
Applications from job seekers who require current Skilled worker sponsorship to work in the UK are welcome and will be considered alongside all other applications. For further information visit the UK Visas and Immigration website (Opens in a new tab).
From 6 April 2017, skilled worker applicants, applying for entry clearance into the UK, have had to present a criminal record certificate from each country they have resided continuously or cumulatively for 12 months or more in the past 10 years. Adult dependants (over 18 years old) are also subject to this requirement. Guidance can be found here Criminal records checks for overseas applicants (Opens in a new tab).
UK Registration
Applicants must have current UK professional registration. For further information please see
NHS Careers website (opens in a new window).
