Job summary
GUY'S AND ST. THOMAS' HOSPITAL NHS FOUNDATION TRUST Senior Clinical Research Fellow in Clinical Oncology (Uro-Oncology / Prostate Cancer Radiotherapy) - OPEN Trial
Part Time - 0.8 Fixed Term - 12 months
Guy's and St Thomas' NHS Foundation Trust is seeking to appoint a Senior Clinical Research Fellow in Clinical Oncology (Uro-oncology) to support the delivery of a major translational clinical research programme focused on improving outcomes for patients undergoing radiotherapy for prostate cancer.
The successful candidate will play a key role in supporting a randomised phase III clinical trial evaluating the use of a prebiotic to prevent radiation enteropathy in patients undergoing pelvic radiotherapy for prostate cancer. The study aims to recruit approximately 320 patients and includes comprehensive clinical phenotyping alongside the collection of biological samples to support microbiome and metabolomic analyses.
Please see attached documents for full JD/PS
Main duties of the job
The post-holder will play a key role in the setup, coordination and delivery of translational and clinical research studies, most particularly a randomised phase III trial investigating interventions to prevent radiation enteropathy in patients undergoing pelvic radiotherapy for prostate cancer.
Responsibilities will include:
- Supporting trial setup and regulatory processes, including collaboration with research governance teams.
- Leading and supporting patient recruitment to clinical trials within the prostate cancer radiotherapy programme.
- Conducting trial-related clinical assessments and follow-up, ensuring adherence to study protocols and Good Clinical Practice (GCP).
- Supporting the collection and processing of biological samples for translational research, including samples used for microbiome and metabolomic analyses.
- Contributing to the development and maintenance of research biobanks and associated datasets.
- working closely with multidisciplinary collaborators including clinical oncologists, microbiome scientists, translational researchers, statisticians and trial management teams.
Please see attached documents for full JD/PS
About us
Guy's and St Thomas' NHS Foundation Trust
Guy's and St Thomas' is among the UK's busiest and most successful NHS foundation trusts. We provide a full range of hospital and community services for people in south London and as well as specialist care for patients from further afield including cancer, renal, orthopaedic, respiratory and cardiovascular services.
Guy's is home to the largest dental school in Europe and a £160 million Cancer Centre opened in 2016. As part of our commitment to provide care closer to home, in 2017 we also opened a cancer centre and a kidney treatment centre at Queen Mary's Hospital in Sidcup. St Thomas' has one of the largest critical care units in the UK and one of the busiest emergency departments in London. It is also home to Evelina London Children's Hospital.
Evelina London cares for local children in Lambeth and Southwark and provides specialist services across south east England including cardiac, renal and critical care services. We lead a number of specialist service networks aiming to ensure children are treated locally where possible, but have access to specialist expertise when they need it. Our community services include health visiting, school nursing and support for families of children with long-term conditions.
Job description
Job responsibilities
Clinical activity will besupernumerary to the core clinical service, allowing the post-holder to focus primarily on research delivery while maintaining appropriate clinical engagement within the uro-oncology service.
The post-holder will:
- Contribute to uro-oncology clinics, particularly those related to the management of prostate cancer patients undergoing radiotherapy.
- Work closely with the prostate cancer multidisciplinary team (MDT), including participation in relevant MDT discussions where appropriate.
- Develop and lead research-focused clinics in collaboration with the prostate cancer team to support patient recruitment and follow-up within clinical studies.
- Support the clinical care of patients participating in research studies, including management of treatment-related toxicities and trial-specific assessments.
- Provide supervision and support to Specialty Registrars (SpRs) and contribute to the education and training of junior medical staff within the department.
- Maintain up-to-date knowledge and skills in clinical oncology practice, particularly in prostate cancer radiotherapy.
Please see attached documents for full JD/PS
Job description
Job responsibilities
Clinical activity will besupernumerary to the core clinical service, allowing the post-holder to focus primarily on research delivery while maintaining appropriate clinical engagement within the uro-oncology service.
The post-holder will:
- Contribute to uro-oncology clinics, particularly those related to the management of prostate cancer patients undergoing radiotherapy.
- Work closely with the prostate cancer multidisciplinary team (MDT), including participation in relevant MDT discussions where appropriate.
- Develop and lead research-focused clinics in collaboration with the prostate cancer team to support patient recruitment and follow-up within clinical studies.
- Support the clinical care of patients participating in research studies, including management of treatment-related toxicities and trial-specific assessments.
- Provide supervision and support to Specialty Registrars (SpRs) and contribute to the education and training of junior medical staff within the department.
- Maintain up-to-date knowledge and skills in clinical oncology practice, particularly in prostate cancer radiotherapy.
Please see attached documents for full JD/PS
Person Specification
QUALIFICATIONS AND TRAINING:
Essential
- MBBS or equivalent
- CCT in Clinical Oncology or within 12 months of obtaining CCT
- PhD in a relevant field (e.g. oncology, translational medicine, microbiome science) or expected completion by 2026
PROFESSIONAL/STATUTORY REGISTRATION
Essential
- Full registration with the General Medical Council (GMC) with licence to practise
Research Experience
Essential
- Evidence of excellent academic performance and research productivity relative to career stage
- Experience working in a multidisciplinary academic research environment
- Experience in microbiome research within oncology
Desirable
- Experience supervising students or research staff
- Evidence of publication in peer-reviewed journals and academic presentation in national and/or international conferences
Skills
Essential
- Ability to work effectively within multidisciplinary clinical and academic teams
- Excellent written and verbal communication skills
- Demonstrated ability to deliver complex research projects and meet deadlines
- Evidence of strong work ethic, initiative and commitment to academic medicine
- Commitment to high standards of clinical care, research integrity and professional conduct
- Satisfactory pre-employment health screening
- Relevant Medical indemnity.
Knowledge
Essential
- Experience working within Clinical Oncology in the NHS
- Experience in the management of prostate cancer patients undergoing radiotherapy
- Knowledge of radiotherapy treatment pathways and toxicity management in prostate cancer
- Experience of working within a multidisciplinary cancer team (MDT)
Desirable
- Broader experience in uro-oncology clinical trials
- Good understanding of microbiome interactions with cancer and its therapies
Person Specification
QUALIFICATIONS AND TRAINING:
Essential
- MBBS or equivalent
- CCT in Clinical Oncology or within 12 months of obtaining CCT
- PhD in a relevant field (e.g. oncology, translational medicine, microbiome science) or expected completion by 2026
PROFESSIONAL/STATUTORY REGISTRATION
Essential
- Full registration with the General Medical Council (GMC) with licence to practise
Research Experience
Essential
- Evidence of excellent academic performance and research productivity relative to career stage
- Experience working in a multidisciplinary academic research environment
- Experience in microbiome research within oncology
Desirable
- Experience supervising students or research staff
- Evidence of publication in peer-reviewed journals and academic presentation in national and/or international conferences
Skills
Essential
- Ability to work effectively within multidisciplinary clinical and academic teams
- Excellent written and verbal communication skills
- Demonstrated ability to deliver complex research projects and meet deadlines
- Evidence of strong work ethic, initiative and commitment to academic medicine
- Commitment to high standards of clinical care, research integrity and professional conduct
- Satisfactory pre-employment health screening
- Relevant Medical indemnity.
Knowledge
Essential
- Experience working within Clinical Oncology in the NHS
- Experience in the management of prostate cancer patients undergoing radiotherapy
- Knowledge of radiotherapy treatment pathways and toxicity management in prostate cancer
- Experience of working within a multidisciplinary cancer team (MDT)
Desirable
- Broader experience in uro-oncology clinical trials
- Good understanding of microbiome interactions with cancer and its therapies
Disclosure and Barring Service Check
This post is subject to the Rehabilitation of Offenders Act (Exceptions Order) 1975 and as such it will be necessary for a submission for Disclosure to be made to the Disclosure and Barring Service (formerly known as CRB) to check for any previous criminal convictions.
UK Registration
Applicants must have current UK professional registration. For further information please see
NHS Careers website (opens in a new window).
Additional information
Disclosure and Barring Service Check
This post is subject to the Rehabilitation of Offenders Act (Exceptions Order) 1975 and as such it will be necessary for a submission for Disclosure to be made to the Disclosure and Barring Service (formerly known as CRB) to check for any previous criminal convictions.
UK Registration
Applicants must have current UK professional registration. For further information please see
NHS Careers website (opens in a new window).
