University Hospital Southampton NHS Trust

Senior Clinical Trials Assistant

The closing date is 13 January 2026

Job summary

University Hospital Southampton NHS Foundation Trust is delighted to offer a fantastic opportunity to work with us.

Please see below for detailed job description of the role.

Main duties of the job

We are seeking a motivated and experienced Senior Clinical Trials Assistant to join the Cystic Fibrosis (CF) and Bronchiectasis Research Team within our Clinical Research Facility. This is an exciting opportunity to play a key role in the delivery of high-quality clinical research studies, supporting both participants and the wider multidisciplinary research team.

The post holder will assist in the delivery of clinical research studies, providing direct patient care alongside essential administrative and organisational support. You will be responsible for organising and managing your own workload, including the day-to-day coordination and implementation of delegated clinical trials, ensuring studies are conducted in line with protocols, Good Clinical Practice (GCP), and regulatory requirements.

You will be expected to develop and maintain clinical knowledge and practical skills relevant to the role, enabling you to provide a consistently high standard of care to participants and volunteers taking part in research studies. Working within your scope of competence, you will deliver direct clinical care and undertake a range of clinical tasks and observations. These will include, but are not limited to, venepuncture, manual and electronic blood pressure measurement, recording ECGs, and performing anthropometric measurements such as height and weight.

About us

University Hospital Southampton is one of England's largest acute teaching Trusts, offering a wide range of learning and development opportunities to support your career aspirations.

Located on the south coast with an international airport and direct rail links to London, Southampton offers an ideal setting to live and work, with the New Forest, South Downs and Jurassic Coast.

We believe that using technology wisely shows strong time management and commitment to innovation. However, personalizing your recruitment application to highlight your unique skills and experiences is crucial. Relying too heavily on generic, AI-generated content instead of drawing from your own strengths and accomplishments may lead to your application being rejected if multiple candidates present identical or similar information.

At UHS we're committed to providing a flexible working environment where possible. Whether you are balancing family, study, or your wellbeing with your career, we want to support you so you can help our patients.

At UHS, we proudly champion individuality, recognizing that outstanding care is only possible with a diverse, inclusive team. We're committed to creating an anti-racist, anti-discriminatory environment where everyone feels valued, safe, and empowered to make a meaningful impact in our communities. We welcome applicants of all backgrounds, identities, and experiences to join us in building a healthcare community where everyone can belong, thrive, and contribute.

Date posted

30 December 2025

Pay scheme

Agenda for change

Band

Band 4

Salary

£27,485 to £30,162 a year Per Annum (PA) Pro Rata

Contract

Permanent

Working pattern

Full-time, Part-time, Flexible working

Reference number

188-THQ141225

Job locations

University Hospital Southampton

Tremona Road

Southampton

SO16 6YD

Job description

Job responsibilities

The successful candidate will demonstrate excellent communication and organisational skills, a patient-centred approach, and the ability to work both independently and as part of a multidisciplinary team. Previous experience in clinical research, respiratory care, or working with CF and/or bronchiectasis patients would be advantageous.

This role offers the opportunity to contribute to innovative research aimed at improving outcomes for people living with CF and bronchiectasis, within a supportive and forward-thinking research environment.

The Senior Clinical Trials Assistant will play a key role in the delivery of high-quality clinical research studies, providing direct patient care, study coordination, and administrative support within a Clinical Research Facility.

Working as part of a multidisciplinary research team, the post holder will support interventional and observational studies from set-up through to close-out, ensuring all research activities are conducted in accordance with Good Clinical Practice (GCP), regulatory requirements, and study protocols.

Assist in the delivery of clinical research studies, providing direct patient care and administrative support

Coordinate and implement delegated interventional and observational studies on a day-to-day basis

Organise and manage own delegated workload to ensure studies are delivered efficiently and to protocol

Deliver direct clinical care to research participants within scope of competence, including:

Venepuncture

Manual and electronic blood pressure measurement

ECG recording

Height and weight (anthropometric measurements)

Develop and maintain clinical and research knowledge to ensure a high standard of participant care

Undertake participant screening, eligibility checks, and informed consent where appropriately delegated

Conduct all research activities in accordance with ICH Good Clinical Practice (GCP), legislation, local policies, and study protocols

Identify, monitor, report, and escalate participant safety concerns and adverse events in line with Trust and research governance requirements

Coordinate study administration including:

Booking and preparing participant appointments and visits

Arranging participant reimbursement for research visits

Accurately complete trial documentation, data entry, and data queries using approved participant records and IT systems

Contribute to the set-up and delivery of new research studies

Arrange shipment of biological samples, data, and equipment nationally and internationally

Maintain stock levels of study consumables, ensuring correct storage and timely replenishment

Act as the first point of telephone contact for research enquiries, providing appropriate clinical and non-clinical information within role boundaries

Prepare for and support monitoring visits, including documentation preparation and acting as a liaison during visits

Maintain a clean, safe, and secure environment for participants and staff

Develop and promote effective working relationships within a multidisciplinary team

Act as a role model and ambassador for clinical research, supporting and guiding junior staff where appropriate

Recognise professional boundaries, escalating concerns appropriately and undertaking training to maintain competence

Participate in and deliver staff training by sharing knowledge and experience

Provide a flexible service, including 24/7 working as required to meet participant, study, and service needs