Job summary
The Cambridge Clinical Trials Unit (CCTU) is part of the NIHR UKCRC Registered CTU Network with the remit to provide support for all aspects of clinical trials from set-up to close down within the Cambridge Biomedical Research Centre.
Applications are invited for the post of Clinical Trials Manager in the CCTU which provides support for clinical trials within the Biomedical Research Centre. The post is based within the CCTU Core and Cardiovascular Themes.
The Clinical Trials Manager will work in partnership with the CCTU-Cancer Theme Operations Manager, CCTC Director, Senior CCTU staff and members of individual trial teams to ensure the smooth and efficient conceptualisation, set-up, delivery and reporting of trials that are led and run by CCTU. On a daily basis, lead project management for trials under their remit and ensure that staff follow relevant CCTU SOPs, CUH policies and UK Regulations.
Previous experience of working in a clinical research environment within the NHS, University or pharmaceutical industry is essential for this post together with significant knowledge and experience of UK regulations, guidelines and requirements for the conduct of clinical research. Project management experience, as well as understanding of advanced therapy and device trials would be advantageous.
Main duties of the job
To lead clinical trial project management for designated trials within CCTU-Cancer Theme, including interaction and work flow between key CCTU staff involved in trial delivery e.g. coordination, data management, statistics, QA, Investigators and the trial management group.
Develop the CCTU clinical trials coordination and trial management function under the direction of the CCTC Director and CCTU-Cancer Theme Operations Manager across cancer trials.
To advise researchers on trial design, feasibility, trial management costs and approvals and processes.
To maintain oversight of trial set-up, delivery and reporting and provide project management for the financial aspects of the trial activity.
To ensure that all GCP and other statutory requirements are met during the conduct and coordination of these clinical trials.
About us
Our Trust
Cambridge University Hospitals (CUH) NHS Foundation Trust comprises Addenbrooke's Hospital and the Rosie Hospital in Cambridge. With over 13,000 staff and over 1100 beds the priorities of the Trust focus on a quality service which is all about people - patients, staff and partners. Recognised as providing 'outstanding' care to our patients and rated 'Good' overall by the Care Quality Commissioner, is testament to the skill and dedication of the people who work here. CUH's values - Together - Safe, Kind, Excellent - are at the heart of patient care, defining the way all staff work and behave. The Trust provides accessible high-quality healthcare for the local people of Cambridge, together with specialist services, dealing with rare or complex conditions for a regional, national and international population.
CUH is committed to promoting a diverse and inclusive community - a place where we can all be ourselves. We value our differences and fully advocate and support an inclusive working environment where every individual can fulfil their potential. We want to ensure our people are truly representative of all the communities that we serve. We welcome applications for all positions in the organisation irrespective of people's age, disability, ethnicity, race, nationality, gender identity, sex, sexual orientation, religion or belief, marriage and civil partnership status, or pregnancy and maternity status or social economic background.
Job description
Job responsibilities
Please see the attached Applicant Information Pack (combined Job Description and Person Specification) for key duties and responsibilities.
Due to Home Office immigration rules, a full time permanent vacancy cannot be filled by individuals on a Student visa. Therefore, please be advised that if you are a Student visa holder, we will not be able to offer you a full time permanent contract unless you have:- applied for a Graduate visa- or you will have successfully completed your course and have applied for a Graduate visa before the anticipated start date of your employment- or the Trust has agreed that they will Sponsor you as a Skilled Worker and you will complete your studies within 3 months of the anticipated start date of employment
This vacancy will close at midnight on the 23rd February 2026.
Interview date to be confirmed.
Benefits to you
At Cambridge University Hospitals, we want to do all we can to support good working days. We offer development opportunities and a wide range of benefits, including on-site leisure facilities, shopping concourse and day nurseries. Our good work programme currently includes providing reduced cost Stagecoach bus travel to and from Cambridge University Hospital site. Park and Ride bus journeys between Babraham Road and Trumpington sites are free, as is the route to and from Cambridge train station and our hospitals. We also subsidise the cost of parking on site for eligible staff.
On CUH campus, hot food is available 24/7 and at a reduced cost for colleagues. Recently we launched the first of our staff pod break spaces. Located in the Deakin Centre, we have a purpose-created colleague-only caf, with free tea and coffee, a break space and private outside area for colleagues to rest, refuel and recharge. Just one of the ways we are working hard to support good working days at CUH.
CUH is committed to assisting employees in achieving a good work-life balance irrespective of role or personal circumstances. Flexible arrangements may include, but are not limited to, part-time working, job-share, term-time working and flexible start and finish times.
Please note if you would like to discuss the required hours of this role further, you should approach the contact given. In some cases, alternative working hours will be considered.
We welcome applications from the Armed Forces.
Job description
Job responsibilities
Please see the attached Applicant Information Pack (combined Job Description and Person Specification) for key duties and responsibilities.
Due to Home Office immigration rules, a full time permanent vacancy cannot be filled by individuals on a Student visa. Therefore, please be advised that if you are a Student visa holder, we will not be able to offer you a full time permanent contract unless you have:- applied for a Graduate visa- or you will have successfully completed your course and have applied for a Graduate visa before the anticipated start date of your employment- or the Trust has agreed that they will Sponsor you as a Skilled Worker and you will complete your studies within 3 months of the anticipated start date of employment
This vacancy will close at midnight on the 23rd February 2026.
Interview date to be confirmed.
Benefits to you
At Cambridge University Hospitals, we want to do all we can to support good working days. We offer development opportunities and a wide range of benefits, including on-site leisure facilities, shopping concourse and day nurseries. Our good work programme currently includes providing reduced cost Stagecoach bus travel to and from Cambridge University Hospital site. Park and Ride bus journeys between Babraham Road and Trumpington sites are free, as is the route to and from Cambridge train station and our hospitals. We also subsidise the cost of parking on site for eligible staff.
On CUH campus, hot food is available 24/7 and at a reduced cost for colleagues. Recently we launched the first of our staff pod break spaces. Located in the Deakin Centre, we have a purpose-created colleague-only caf, with free tea and coffee, a break space and private outside area for colleagues to rest, refuel and recharge. Just one of the ways we are working hard to support good working days at CUH.
CUH is committed to assisting employees in achieving a good work-life balance irrespective of role or personal circumstances. Flexible arrangements may include, but are not limited to, part-time working, job-share, term-time working and flexible start and finish times.
Please note if you would like to discuss the required hours of this role further, you should approach the contact given. In some cases, alternative working hours will be considered.
We welcome applications from the Armed Forces.
Person Specification
Qualifications
Essential
- Relevant science postgraduate qualification or equivalent.
Desirable
- Research related qualification, for example research-based Master degree or similar.
- Project Management qualification.
Experience
Essential
- Extensive staff line management experience.
- Extensive experience in set-up, managing and coordination of Clinical Trials.
- Managing a team of clinical trial coordinators and data managers.
- Extensive experience of UK regulations on clinical trials.
- Writing protocols, grant applications.
- Identification of research cost associated with clinical trials; costing for grant applications.
- Submissions of MHRA / Ethics / HRA applications.
- IMP management and requirements.
Desirable
- Experience of complex CTIMP studies, advanced therapy trials, and/or medical devices and/or epidemiological studies.
- Working in the NHS/ University research environement with consultants and academic investigators.
- Project management, ability determine mile stones and realistic time lines.
- R & D/University research contract negotiations.
- CRF design and data base requirements.
Knowledge
Essential
- Research Methodology, study design.
- Good Clinical Practice.
- EU Clinical Trials Directive.
Desirable
- Funding for academic research.
- Process of grant applications.
Skills
Essential
- Excellent organisational and communication skills.
- Good workload management.
- Ability to liaise with a wide range of staff, including principal investigators and their teams.
- Ability to communicate complex regulatory issues in a clear and logic way.
- Fully Computer Literate and Experience with using trial databases.
- Experience in producing and presenting reports, including financial report.
- Ability to present data in clear and simple format.
Desirable
- High level of computer literacy.
- Use of specialist IT programmes like MACRO, ReDa, IQM- Quality management.
- Trial database design.
- Recruitment, selection and appraisal skills.
Additional Requirements
Essential
- Ability to work and lead a team.
- Able to use own initiative and under pressure.
- Able to keep up to date with legal and ethical, scientific requirement for clinical research.
- Understanding of the need for and principles of accurate and timely data collection and reporting.
- The ability to understand and behave at all times, towards patients, visitors and colleagues according to the Trust values of safe, kind, excellent.
Desirable
- Understanding the needs of research active investigators from NHS Trust and University.
Person Specification
Qualifications
Essential
- Relevant science postgraduate qualification or equivalent.
Desirable
- Research related qualification, for example research-based Master degree or similar.
- Project Management qualification.
Experience
Essential
- Extensive staff line management experience.
- Extensive experience in set-up, managing and coordination of Clinical Trials.
- Managing a team of clinical trial coordinators and data managers.
- Extensive experience of UK regulations on clinical trials.
- Writing protocols, grant applications.
- Identification of research cost associated with clinical trials; costing for grant applications.
- Submissions of MHRA / Ethics / HRA applications.
- IMP management and requirements.
Desirable
- Experience of complex CTIMP studies, advanced therapy trials, and/or medical devices and/or epidemiological studies.
- Working in the NHS/ University research environement with consultants and academic investigators.
- Project management, ability determine mile stones and realistic time lines.
- R & D/University research contract negotiations.
- CRF design and data base requirements.
Knowledge
Essential
- Research Methodology, study design.
- Good Clinical Practice.
- EU Clinical Trials Directive.
Desirable
- Funding for academic research.
- Process of grant applications.
Skills
Essential
- Excellent organisational and communication skills.
- Good workload management.
- Ability to liaise with a wide range of staff, including principal investigators and their teams.
- Ability to communicate complex regulatory issues in a clear and logic way.
- Fully Computer Literate and Experience with using trial databases.
- Experience in producing and presenting reports, including financial report.
- Ability to present data in clear and simple format.
Desirable
- High level of computer literacy.
- Use of specialist IT programmes like MACRO, ReDa, IQM- Quality management.
- Trial database design.
- Recruitment, selection and appraisal skills.
Additional Requirements
Essential
- Ability to work and lead a team.
- Able to use own initiative and under pressure.
- Able to keep up to date with legal and ethical, scientific requirement for clinical research.
- Understanding of the need for and principles of accurate and timely data collection and reporting.
- The ability to understand and behave at all times, towards patients, visitors and colleagues according to the Trust values of safe, kind, excellent.
Desirable
- Understanding the needs of research active investigators from NHS Trust and University.
Disclosure and Barring Service Check
This post is subject to the Rehabilitation of Offenders Act (Exceptions Order) 1975 and as such it will be necessary for a submission for Disclosure to be made to the Disclosure and Barring Service (formerly known as CRB) to check for any previous criminal convictions.
Applications from job seekers who require current Skilled worker sponsorship to work in the UK are welcome and will be considered alongside all other applications. For further information visit the UK Visas and Immigration website (Opens in a new tab).
From 6 April 2017, skilled worker applicants, applying for entry clearance into the UK, have had to present a criminal record certificate from each country they have resided continuously or cumulatively for 12 months or more in the past 10 years. Adult dependants (over 18 years old) are also subject to this requirement. Guidance can be found here Criminal records checks for overseas applicants (Opens in a new tab).
Additional information
Disclosure and Barring Service Check
This post is subject to the Rehabilitation of Offenders Act (Exceptions Order) 1975 and as such it will be necessary for a submission for Disclosure to be made to the Disclosure and Barring Service (formerly known as CRB) to check for any previous criminal convictions.
Applications from job seekers who require current Skilled worker sponsorship to work in the UK are welcome and will be considered alongside all other applications. For further information visit the UK Visas and Immigration website (Opens in a new tab).
From 6 April 2017, skilled worker applicants, applying for entry clearance into the UK, have had to present a criminal record certificate from each country they have resided continuously or cumulatively for 12 months or more in the past 10 years. Adult dependants (over 18 years old) are also subject to this requirement. Guidance can be found here Criminal records checks for overseas applicants (Opens in a new tab).